Towards ultrahigh throughput microinjection: MEMS-based massively-parallelized mechanoporation

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dc.contributor.authorZhang, Yanyan
dc.contributor.authorBallas, Christopher B.
dc.contributor.authorRao, Masaru P.
dc.contributor.departmentDepartment of Medicine, IU School of Medicineen_US
dc.date.accessioned2016-04-01T16:48:55Z
dc.date.available2016-04-01T16:48:55Z
dc.date.issued2012
dc.description.abstractWe describe a massively-parallelized, MEMS-based device concept for passively delivering exogeneous molecules into living cells via mechanical membrane penetration, i.e., mechanoporation. Details regarding device design and fabrication are discussed, as are results from preliminary live cell studies focused on device validation at the proof-of-concept level. These efforts represent key steps towards our long-term goal of developing instrumentation capable of ultrahigh throughput (UHT) cellular manipulation via active microinjection.en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationZhang, Y., Ballas, C. B., & Rao, M. P. (2012). Towards Ultrahigh Throughput Microinjection: MEMS-based Massively-parallelized Mechanoporation. Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2012, 594–597. http://doi.org/10.1109/EMBC.2012.6346001en_US
dc.identifier.urihttps://hdl.handle.net/1805/9172
dc.language.isoen_USen_US
dc.publisherInstitute of Electrical and Electronics Engineersen_US
dc.relation.isversionof10.1109/EMBC.2012.6346001en_US
dc.relation.journalConference proceedings: ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conferenceen_US
dc.rightsPublisher Policyen_US
dc.sourcePMCen_US
dc.subjectMicro-Electrical-Mechanical Systemsen_US
dc.subjectinstrumentationen_US
dc.subjectMicroinjectionsen_US
dc.titleTowards ultrahigh throughput microinjection: MEMS-based massively-parallelized mechanoporationen_US
dc.typeConference proceedingsen_US
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