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Defining comprehensive biomarker‐related testing and treatment practices for advanced non‐small‐cell lung cancer: Results of a survey of U.S. oncologists
(Wiley, 2022) Mileham, Kathryn F.; Schenkel, Caroline; Bruinooge, Suanna S.; Freeman-Daily, Janet; Basu Roy, Upal; Moore, Amy; Smith, Robert A.; Garrett-Mayer, Elizabeth; Rosenthal, Lauren; Garon, Edward B.; Johnson, Bruce E.; Osarogiagbon, Raymond U.; Jalal, Shadia; Virani, Shamsuddin; Weber Redman, Mary; Silvestri, Gerard A.; Medicine, School of Medicine
Background: An ASCO taskforce comprised of representatives of oncology clinicians, the American Cancer Society National Lung Cancer Roundtable (NLCRT), LUNGevity, the GO2 Foundation for Lung Cancer, and the ROS1ders sought to: characterize U.S. oncologists' biomarker ordering and treatment practices for advanced non-small-cell lung cancer (NSCLC); ascertain barriers to biomarker testing; and understand the impact of delays on treatment decisions.
Methods: We deployed a survey to 2374 ASCO members, targeting U.S. thoracic and general oncologists.
Results: We analyzed 170 eligible responses. For non-squamous NSCLC, 97% of respondents reported ordering tests for EGFR, ALK, ROS1, and BRAF. Testing for MET, RET, and NTRK was reported to be higher among academic versus community providers and higher among thoracic oncologists than generalists. Most respondents considered 1 (46%) or 2 weeks (52%) an acceptable turnaround time, yet 37% usually waited three or more weeks to receive results. Respondents who waited ≥3 weeks were more likely to defer treatment until results were reviewed (63%). Community and generalist respondents who waited ≥3 weeks were more likely to initiate non-targeted treatment while awaiting results. Respondents <5 years out of training were more likely to cite their concerns about waiting for results as a reason for not ordering biomarker testing (42%, vs. 19% with ≥6 years of experience).
Conclusions: Respondents reported high biomarker testing rates in patients with NSCLC. Treatment decisions were impacted by test turnaround time and associated with practice setting and physician specialization and experience.
American Singles’ Attitudes Toward Future Romantic/ Sexual Partners’ COVID-19 Vaccination Status: Evidence for both Vigilance and Indifference in a National Sample
(Springer, 2023-05-18) Campbell, Jessica T.; Bennett-Brown, Magaret; Marcotte, Alexandra S.; Kaufman, Ellen M.; Moscovici, Zoe; Adams, Olivia R.; Lovins, Sydney; Garcia, Justin R.; Gesselman, Amanda N.
Around 142 million American adults are currently single; at least half of these singles want to pursue a romantic partner. Romantic dating can involve exposure to numerous people. Thus, dating can significantly impact pathogen exposure risk. In a demographically-representative cross-sectional survey conducted in 2021 (N = 5,000), we examined U.S. American singles' COVID-19 vaccination status, assessed their preferences around a potential partner's COVID-19 vaccination status, and identified demographic subgroups of singles particularly opposed to or indifferent to a partner being vaccinated against COVID-19. Our results showed 65% of participants were fully vaccinated, 10% were partially vaccinated, and 26% were unvaccinated against COVID-19. With regards to partner preferences, half wanted a vaccinated partner; 18.9% wanted a vaccinated partner but would make exceptions; 6.1% wanted an unvaccinated partner; and 25% reported that they did not care about their dating partner's vaccination status. Partner preferences were largely aligned with participants' own vaccination status, such that vaccinated participants preferred vaccinated partners. However, those preferring unvaccinated partners-or those willing to make exceptions for a partner-were most likely to identify as men, younger in age, a political affiliation outside of the two-party political system, a gender or sexual minority, or as a racial minority (i.e., Black/African-American or South Asian). Additionally, participants who were employed (vs. unemployed) were more likely to make exceptions for or prefer an unvaccinated partner. These results suggest that singles prefer homophily in COVID-19 vaccine status, and that minoritized subgroups of singles are more likely to maintain a social network including unvaccinated close others.
2023 Direct Assessment of University Profiles through Written Reflections of Engaged Learning Experiences Using the AAC&U Written Communication, Integrative Learning, and Civic Engagement VALUE Rubrics
(2023-11-01) Hahn, Thomas
This report describes a direct assessment activity within the IUPUI Institute for Engaged Learning (IEL) for students participating in IEL programs during AY 2022-2023. The IEL Assessment Workgroup assessed written reflection artifacts of 100 students from 6 co-curricular programs. Using selected rows from the Written Communication, Integrative Learning, and Civic Engagement VALUE Rubrics, the raters assessed the Communicator, Problem Solver, and Community Contributor Profiles of Undergraduate Learning.
"I Bring Her up with Love': Perspectives of Caregivers of Children with Neurodevelopmental Delays in Western Kenya
(2023-01) Heng, Yi Yan; Nafiseh, Amira; Oyungu, Eren; Ombitsa, Ananda Roselyne; Cherop, Carolyn; McHenry, Megan S.
Objective: This study aims to understand the challenges and perspectives of caregivers with neurodevelopmental delays (NDD) in rural Kenya.
Methods: Semi-structured interviews and the Affiliate Stigma Scale were administered to the primary caregivers of children with NDDs recruited from the
communities near Eldoret, Kenya. Constant comparison and triangulation methods were used to inductively develop relevant themes and concepts.
Results: Sixteen caregivers participated. Challenges, which included hardships related to safety and supervision, challenging emotions and financial difficulties, were compounded by a lack of social support and community stigma towards these children. However, caregivers still felt deep love for their children, desired
acceptance from the community and found sources of strength from faith and religious institutions.
Conclusion: The study uncovered crucial insights into the perspectives of caregivers within this population and revealed a paucity of disability awareness and
understanding within the community, possibly informing future programmes and intervention policies.
Clarifying Jurisdiction in the Library Workforce: Tasks, Support Staff, and Professional Librarians
(Johns Hopkins University Press, 2010) Applegate, Rachel
Jurisdiction refers to those tasks or responsibilities that are seen as central to and exclusively controlled by a profession. When library work is examined, what is the proper jurisdiction for professional, masters-level librarians? This study examines the definition of professional with respect to library workers by using data from a national survey of competencies for library support staff and by comparing American Library Association-approved competencies for beginning MLS librarians and certified support staff. According to this analysis, professional librarians are those who know context (history, theory), do research, educate patrons, and manage people and collections. They are not necessarily those who provide direct services.