• A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH 

  Ueda, Mitsuharu; Okada, Masamitsu; Mizuguchi, Mineyuki; Kluve-Beckerman, Barbara; Kanenawa, Kyosuke; Isoguchi, Aito; Misumi, Yohei; Tasaki, Masayoshi; Ueda, Akihiko; Kanai, Akinori; Sasaki, Ryoko; Masuda, Teruaki; Inoue, Yasuteru; Nomura, Toshiya; Shinriki, Satoru; Shuto, Tsuyoshi; Kai, Hirofumi; Yamashita, Taro; Matsui, Hirotaka; Benson, Merrill D.; Ando, Yukio (Elsevier, 2019-07-19)

  Transthyretin (TTR) is a major amyloidogenic protein associated with hereditary (ATTRm) and nonhereditary (ATTRwt) intractable systemic transthyretin amyloidosis. The pathological mechanisms of ATTR-associated amyloid ...
• The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes 

  Nakayasu, Ernesto S.; Qian, Wei-Jun; Evans-Molina, Carmella; Mirmira, Raghavendra G.; Eizirik, Decio L.; Metz, Thomas O. (Taylor & Francis, 2019-06-24)

  Introduction: Type 1 diabetes (T1D) is characterized by autoimmune-induced dysfunction and destruction of the pancreatic beta cells. Unfortunately, this process is poorly understood, and the current best treatment for ...
• A natural language processing framework to analyse the opinions on HPV vaccination reflected in twitter over 10 years (2008 - 2017) 

  Luo, Xiao; Zimet, Gregory; Shah, Setu (Taylor & Francis, 2019-07-16)

  In this research, we developed a natural language processing (NLP) framework to investigate the opinions on HPV vaccination reflected on Twitter over a 10-year period – 2008–2017. The NLP framework includes sentiment ...
• Associations between HPV vaccination among women and their 11–14-year-old children 

  Kornides, Melanie; Head, Katharine J.; Feemster, Kristen; Zimet, Gregory D.; Panozzo, Catherine A. (Taylor & Francis, 2019-01-07)

  The human papillomavirus (HPV) vaccine has been available in the United States for over a decade. We sought to examine the associations between self-reported receipt of HPV vaccination among women and their 11–14-year-old ...
• Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome 

  Wang, Guohua; Wang, Xin; Wang, Yadong; Yang, Jack Y.; Li, Lang; Nephew, Kenneth P.; Edenberg, Howard J.; Zhou, Feng C.; Liu, Yunlong (BioMed Central, 2008-03-20)

  This is a first report, using our MotifModeler informatics program, to simultaneously identify transcription factor (TF) and microRNA (miRNA) binding sites from gene expression microarray data. Based on the assumption that ...

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