Interleukin-13 Is Unlucky for Allergy Sufferers

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2019-10
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English
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Abstract

Anaphylaxis, a life-threatening allergic reaction, is dependent on high affinity allergen-specific IgE. Gowthaman et al . now show that a new interleukin (IL)-13-expressing T helper cell subset specifically promotes high-affinity IgE responses. The discovery of T follicular helper (Tfh)13 cells defines potential new targets for allergy therapies.

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Xie, M. M., & Dent, A. L. (2019). Interleukin-13 Is Unlucky for Allergy Sufferers. Trends in Pharmacological Sciences, 40(10), 714–716. https://doi.org/10.1016/j.tips.2019.08.007
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