Narrow-band imaging versus white light for the detection of proximal colon serrated lesions: a randomized, controlled trial

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dc.contributor.authorRex, Douglas K.
dc.contributor.authorClodfelter, Ryan
dc.contributor.authorRahmani, Farrah
dc.contributor.authorFatima, Hala
dc.contributor.authorJames-Stevenson, Toyia N.
dc.contributor.authorTang, John C.
dc.contributor.authorKim, Hak Nam
dc.contributor.authorMcHenry, Lee
dc.contributor.authorKahi, Charles J.
dc.contributor.authorRogers, Nicholas A.
dc.contributor.authorHelper, Debra J.
dc.contributor.authorSagi, Sashidhar V.
dc.contributor.authorKessler, William R.
dc.contributor.authorWo, John M.
dc.contributor.authorFischer, Monika
dc.contributor.authorKwo, Paul Y.
dc.contributor.departmentDepartment of Medicine, School of Medicineen_US
dc.date.accessioned2017-10-19T18:17:05Z
dc.date.available2017-10-19T18:17:05Z
dc.date.issued2016-01
dc.description.abstractBackground The value of narrow-band imaging (NBI) for detecting serrated lesions is unknown. Objective To assess NBI for the detection of proximal colon serrated lesions. Design Randomized, controlled trial. Setting Two academic hospital outpatient units. Patients Eight hundred outpatients 50 years of age and older with intact colons undergoing routine screening, surveillance, or diagnostic examinations. Interventions Randomization to colon inspection in NBI versus white-light colonoscopy. Main Outcome Measurements The number of serrated lesions (sessile serrated polyps plus hyperplastic polyps) proximal to the sigmoid colon. Results The mean inspection times for the whole colon and proximal colon were the same for the NBI and white-light groups. There were 204 proximal colon lesions in the NBI group and 158 in the white light group (P = .085). Detection of conventional adenomas was comparable in the 2 groups. Limitations Lack of blinding, endoscopic estimation of polyp location. Conclusion NBI may increase the detection of proximal colon serrated lesions, but the result in this trial did not reach significance. Additional study of this issue is warranted. (Clinical trial registration number: NCT01572428.)en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationRex, D. K., Clodfelter, R., Rahmani, F., Fatima, H., James-Stevenson, T. N., Tang, J. C., … Kwo, P. Y. (2016). Narrow-band imaging versus white light for the detection of proximal colon serrated lesions: a randomized, controlled trial. Gastrointestinal Endoscopy, 83(1), 166–171. https://doi.org/10.1016/j.gie.2015.03.1915en_US
dc.identifier.urihttps://hdl.handle.net/1805/14340
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.gie.2015.03.1915en_US
dc.relation.journalGastrointestinal Endoscopyen_US
dc.rightsIUPUI Open Access Policyen_US
dc.sourceAuthoren_US
dc.subjectnarrow band imagingen_US
dc.subjectserrated lesionsen_US
dc.subjectrandomized controlled trialen_US
dc.titleNarrow-band imaging versus white light for the detection of proximal colon serrated lesions: a randomized, controlled trialen_US
dc.typeArticleen_US
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