p38 MAPK in pancreatic cancer: finding a protective needle in the haystack
| dc.contributor.author | Korc, Murray | |
| dc.contributor.department | Department of Medicine, IU School of Medicine | en_US |
| dc.date.accessioned | 2016-11-23T19:22:36Z | |
| dc.date.available | 2016-11-23T19:22:36Z | |
| dc.date.issued | 2014-12-01 | |
| dc.description.abstract | Activated p38 MAPK alpha (pp38α) is a good prognostic marker in pancreatic ductal adenocarcinoma that could be used to personalize therapy. pp38α suppresses JNK-mediated proliferation, both in vitro and in vivo. These findings support the testing of combination therapies that include JNK targeting and/or suppressing negative regulators of pp38α. | en_US |
| dc.eprint.version | Author's manuscript | en_US |
| dc.identifier.citation | Korc, M. (2014). p38 MAPK in Pancreatic Cancer: Finding a Protective Needle in the Haystack. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 20(23), 5866–5868. http://doi.org/10.1158/1078-0432.CCR-14-1543 | en_US |
| dc.identifier.issn | 1078-0432 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1805/11495 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | American Association for Cancer Research | en_US |
| dc.relation.isversionof | 10.1158/1078-0432.CCR-14-1543 | en_US |
| dc.relation.journal | Clinical Cancer Research: An Official Journal of the American Association for Cancer Research | en_US |
| dc.rights | Publisher Policy | en_US |
| dc.source | PMC | en_US |
| dc.subject | JNK Mitogen-Activated Protein Kinases | en_US |
| dc.subject | metabolism | en_US |
| dc.subject | Pancreatic Neoplasms | en_US |
| dc.subject | pathology | en_US |
| dc.subject | p38 Mitogen-Activated Protein Kinase | en_US |
| dc.title | p38 MAPK in pancreatic cancer: finding a protective needle in the haystack | en_US |
| dc.type | Article | en_US |