• Glucocorticoid-Induced Leucine Zipper in Central Nervous System Health and Disease 

  Srinivasan, Mythily; Lahiri, Debomoy K. (Springer, 2016)

  The central nervous system (CNS) is a large network of intercommunicating cells that function to maintain tissue health and homeostasis. Considerable evidence suggests that glucocorticoids exert both neuroprotective and ...
• Chronic fibrosing osteomyelitis of the jaws: an important cause of recalcitrant facial pain. A clinicopathologic study of 331 cases in 227 patients 

  Goldblatt, Lawrence I.; Adams, William R.; Spolnik, Kenneth J.; Deardorf, Kevin A.; Parks, Edwin T. (Elsevier, 2017)

  Objective This was a retrospective and follow-up analysis of 331 cases of chronic fibrosing osteomyelitis of the jaws (CFOJ) in 227 patients. Study Design Demographic, clinical, surgical, and microscopic characteristics ...
• Is it time to extend synoptic reporting to include potentially preneoplastic oral epithelial and lichenoid lesions? 

  Edwards, Paul C. (Elsevier, 2017-08)
• Epithelial expression of keratinocytes growth factor in oral precancer lesions 

  Jimson, Sudha; Murali, S.; Zunt, Susan L.; Goldblatt, Lawrence I.; Srinivasan, Mythily (2016)

  Background: Keratinocyte growth factor (KGF) is a potent epithelial mitogen that acts by binding the KGF receptors (KGFRs) expressed on epithelial cells and regulates proliferation and differentiation. The objective of ...
• Student perspectives on using Google Glass recordings to assess their communicative and clinical skills with standardized patients 

  Zahl, David A.; Schrader, Stuart M.; Edwards, Paul C. (Wiley, 2016)

  Introduction This exploratory study evaluated student perceptions of their ability to self- and peer assess (i) interpersonal communication skills and (ii) clinical procedures (a head and neck examination) during ...
• Novel Nuclear Factor-KappaB Targeting Peptide Suppresses β-Amyloid Induced Inflammatory and Apoptotic Responses in Neuronal Cells 

  Srinivasan, Mythily; Bayon, Baindu; Chopra, Nipun; Lahiri, Debomoy K. (PLOS, 2016-10-20)

  In the central nervous system (CNS), activation of the transcription factor nuclear factor-kappa B (NF-κβ) is associated with both neuronal survival and increased vulnerability to apoptosis. The mechanisms underlying these ...
• The Patient Educator Presentation in Dental Education: Reinforcing the Importance of Learning About Rare Conditions 

  Edwards, Paul C.; Graham, Jasmine; Oling, Rebecca; Frantz, Kate E. (2016-05)

  The aim of this study was to determine whether a patient educator presentation (PEP) on pemphigus vulgaris would increase second-year dental students’ awareness of the importance of learning about rare conditions and improve ...
• Insight into the pathogenesis and nature of Central Giant Cell Lesions of the Jaws 

  Edwards, Paul C. (Medicina Oral S.L., 2015-03-01)

  Central giant cell lesions of the jaws are not uncommon. While the majority of these represent single, sporadic lesions, histologically identical lesions are seen in association with a number of other bone lesions, as well ...
• Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation 

  Srinivasan, Mythily; Blackburn, Corinne; Lahiri, Debomoy K. (Dove Medical Press, 2014)

  Glucocorticoid-induced leucine zipper (GILZ) is a glucocorticoid responsive protein that links the nuclear factor-kappa B (NFκB) and the glucocorticoid signaling pathways. Functional and binding studies suggest that the ...
• Significance of NF-κΒ as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis 

  Srinivasan, Mythily; Lahiri, Debomoy K. (Taylor and Francis, 2015-04)

  Introduction: Advances in molecular pathogenesis suggest that the chronic inflammation is a shared mechanism in the initiation and progression of multiple neurodegenerative diseases with diverse clinical manifestations ...
• Decreased alveolar bone turnover is related to the occurrence of root resorption during experimental tooth movement in dogs 

  Deguchi, Toru; Seiryu, Masahiro; Daimaruya, Takayoshi; Garetto, Lawrence P.; Takana-Yamamoto, Teruko; Roberts, W. Eugene (2015)

  Objective:  To investigate the relationship between root resorption (RR) and bone turnover in two different types of tooth movement in dogs. Materials and Methods:  A total of 16 dogs in two different groups were used. ...
• Literature-Based Discovery of Salivary Biomarkers for Type 2 Diabetes Mellitus 

  Srinivasan, Mythily; Blackburn, Corinne; Mohamed, Mohamed; Sivagami, A. V.; Blum, Janice (Libertas Academia, 2015-02)

  The alarming increase in type 2 diabetes mellitus (T2DM) underscores the need for efficient screening and preventive strategies. Select protein biomarker profiles emerge over time during T2DM development. Periodic evaluation ...
• Functional characterization of a competitive peptide antagonist of p65 in human macrophage- like cells suggests therapeutic potential for chronic inflammation 

  Srinivasan, Mythily; Blackburn, Corinne; Lahiri, Debomoy (2014-12)

  Glucocorticoid-induced leucine zipper (GILZ) is a glucocorticoid responsive protein that links the nuclear factor-kappa B (NFκB) and the glucocorticoid signaling pathways. Functional and binding studies suggest that the ...
• Soluble toll like receptor 2 (TLR-2) is increased in saliva of children with dental caries 

  Zhao, Alyssa; Blackburn, Corinne; Chin, Judith; Srinivasan, Mythily (2014-08)

  Background Dental caries is the most common microbial disease affecting mankind. Caries risk assessment methods, identification of biomarkers and vaccine development strategies are being emphasized to control the incidence ...
• Cone beam CT evaluation of the presence of anatomic accessory canals in the jaws 

  Eshak, M; Brooks, S; Abdel-Wahed, N; Edwards, Paul C. (2014-05)

  Objectives: To assess the prevalence, location and anatomical course of accessory canals of the jaws using cone beam CT. Methods: A retrospective analysis of 4200 successive cone beam CT scans, for patients of both ...
• Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles 

  Geguchadze, Ramaz; Wang, Zhimin; Zourelias, Lee; Perez-Riveros, Paola; Edwards, Paul C.; Machen, Laurie; Passineau, Michael J (2014-04)

  In this study, we compared gene transfer efficiency and host response to ultrasound-assisted, nonviral gene transfer with a conventional plasmid and a minicircle vector in the submandibular salivary glands of mice. Initially, ...
• Gene-enhanced tissue engineering for dental hard tissue regeneration: (2) dentin-pulp and periodontal regeneration 

  Edwards, Paul C.; Mason, James M (2006-05)

  Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone ...
• Length and Geometric Patterns of the Greater Palatine Canal Observed in Cone Beam Computed Tomography 

  Howard-Swirzinski, Karen; Edwards, Paul C.; Saini, Tarnjit S; Norton, Neil S (2010-07)

  The greater palatine canal is an important anatomical structure that is often utilized as a pathway for infiltration of local anesthesia to affect sensation and hemostasis. Increased awareness of the length and anatomic ...
• Head and Neck Pathology and Radiology 2011 

  Norton, Neil S; Kanjirath, Preetha P; Hita-Iglesias, Pilar; Edwards, Paul C. (2012-12)
• Bisphosphonates Inhibit Expression of p63 by Oral Keratinocytes 

  Scheller, E L; Baldwin, C M; Kuo, S; D'Silva, N J; Feinberg, S E; Krebsbach, P H; Edwards, Paul C. (2011-07)

  Osteonecrosis of the jaw (ONJ), a side-effect of bisphosphonate therapy, is characterized by exposed bone that fails to heal within eight weeks. Healing time of oral epithelial wounds is decreased in the presence of ...

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