• Prenatal fluoride exposure and attention deficit hyperactivity disorder (ADHD) symptoms in children at 6–12 years of age in Mexico City 

  Bashash, Morteza; Marchand, Maelle; Hu, Howard; Till, Christine; Martinez-Mier, E. Angeles; Sanchez, Brisa N.; Basu, Niladri; Peterson, Karen E.; Green, Rivka; Schnaas, Lourdes; Mercado-García, Adriana; Hernández-Avila, Mauricio; Téllez-Rojo, Martha María (Elsevier, 2018-12-01)

  Background Epidemiologic and animal-based studies have raised concern over the potential impact of fluoride exposure on neurobehavioral development as manifested by lower IQ and deficits in attention. To date, no prospective ...
• Healthcare at the Crossroads: The Need to Shapean Organizational Culture of Humanistic Teaching and Practice 

  Rider, Elizabeth A.; Gilligan, MaryAnn C.; Osterberg, Lars G.; Litzelman, Debra K.; Plews-Ogan, Margaret; Weil, Amy B.; Dunne, Dana W.; Hafler, Janet P.; May, Natalie B.; Derse, Arthur R.; Frankel, Richard M.; Branch, William T., Jr. (SpringerLink, 2018-07)

  BACKGROUND: Changes in the organization of medical practice have impeded humanistic practice and resulted in widespread physician burnout and dissatisfaction. OBJECTIVE: To identify organizational factors that promote ...
• Calcium as a cardiovascular toxin in CKD-MBD 

  Moe, Sharon M. (Elsevier, 2017-07)

  Disordered calcium balance and homeostasis are common in patients with chronic kidney disease. Such alterations are commonly associated with abnormal bone remodeling, directly and indirectly. Similarly, positive calcium ...
• Treadmill running and targeted tibial loading differentially improve bone mass in mice 

  Berman, Alycia G.; Hinton, Madicyn J.; Wallace, Joseph M. (Elsevier, 2019-06-01)

  Treadmill running and tibial loading are two common modalities used to assess the role of mechanical stimulation on the skeleton preclinically. The primary advantage of treadmill running is its physiological relevance. ...
• Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank 

  Pardo, Ivanesa; Lillemoe, Heather A.; Blosser, Rachel J.; Choi, MiRan; Sauder, Candice A. M.; Doxey, Diane K.; Mathieson, Theresa; Hancock, Bradley A.; Baptiste, Dadrie; Atale, Rutuja; Hickenbotham, Matthew; Zhu, Jin; Glasscock, Jarret; Storniolo, Anna Maria V.; Zheng, Faye; Doerge, R. W.; Liu, Yunlong; Badve, Sunil S.; Radovich, Milan; Clare, Susan E. (Biomed Central, 2014)

  Introduction Our efforts to prevent and treat breast cancer are significantly impeded by a lack of knowledge of the biology and developmental genetics of the normal mammary gland. In order to provide the specimens that ...
• Endoscopic Ultrasound and Related Technologies for the Diagnosis and Treatment of Pancreatic Disease - Research Gaps and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop 

  Lee, Linda S.; Andersen, Dana K.; Ashida, Reiko; Brugge, William R.; Canto, Mimi I.; Chang, Kenneth J.; Chari, Suresh T.; DeWitt, John; Hwang, Joo Ha; Khashab, Mouen A.; Kim, Kang; Levy, Michael J.; McGrath, Kevin; Park, Walter G.; Singhi, Aatur; Stevens, Tyler; Thompson, Christopher C.; Topazian, Mark D.; Wallace, Michael B.; Wani, Sachin; Waxman, Irving; Yadav, Dhiraj; Singh, Vikesh K. (Lippincott, Williams & Wilkins, 2017)

  A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to address the research gaps and opportunities in pancreatic endoscopic ultrasound (EUS). The event occurred on July 26, 2017 ...
• Phenotypic plasticity in normal breast derived epithelial cells 

  Sauder, Candice A. M.; Koziel, Jillian E.; Choi, MiRan; Fox, Melanie J.; Grimes, Brenda R.; Badve, Sunil S.; Blosser, Rachel J.; Radovich, Milan; Lam, Christina C.; Vaughan, Melville B.; Herbert, Brittney-Shea; Clare, Susan E. (Biomed Central, 2014)

  Background Normal, healthy human breast tissue from a variety of volunteer donors has become available for research thanks to the establishment of the Susan G. Komen for the Cure® Tissue Bank at the IU Simon Cancer Center ...
• Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration 

  Sawe, Rispah T.; Kerper, Maggie; Badve, Sunil S.; Li, Jun; Sandoval-Cooper, Mayra; Xie, Jingmeng; Shi, Zonggao; Patel, Kirtika; Chumba, David; Ofulla, Ayub; Prosperi, Jenifer; Taylor, Katherine; Stack, M. Sharon; Mining, Simeon; Littlepage, Laurie E. (Biomed Central, 2016-03)

  Background Breast cancer incidence and mortality vary significantly among different nations and racial groups. African nations have the highest breast cancer mortality rates in the world, even though the incidence rates ...
• Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer 

  Gökmen-Polar, Yesim; Goswami, Chirayu P.; Toroni, Rachel A.; Sanders, Kerry L.; Mehta, Rutika; Sirimalle, Usha; Tanasa, Bogdan; Shen, Changyu; Li, Lang; Ivan, Mircea; Badve, Sunil S.; Sledge, George W. (Ivyspring, 2014)

  Bevacizumab, the recombinant antibody targeting vascular endothelial growth factor (VEGF), improves progression-free but not overall survival in metastatic breast cancer. To seek further insights in resistance mechanisms ...
• Aberrant nuclear factor-kappa B activity in acute myeloid Leukemia: from molecular pathogenesis to therapeutic target 

  Zhou, Jianbiao; Ching, Ying Qing; Chng, Wee-Joo (Impact, 2015)

  The overall survival of patients with acute myeloid leukemia (AML) has not been improved significantly over the last decade. Molecularly targeted agents hold promise to change the therapeutic landscape in AML. The nuclear ...
• Prospective Validation of a 21-Gene Expression Assay in Breast Cancer 

  Sparano, Joseph A.; Gray, Robert J.; Makower, Della F.; Pritchard, Kathleen I.; Albain, Kathy S.; Hayes, Daniel F.; Geyer, Charles E., Jr.; Dees, Elizabeth C.; Perez, Edith A.; Olson, John A., Jr.; Zujewski, JoAnne; Lively, Tracy; Badve, Sunil S.; Saphner, Thomas J.; Wagner, Lynne I.; Whelan, Timothy J.; Ellis, Matthew J.; Paik, Soonmyung; Wood, William C.; Ravdin, Peter; Keane, Maccon M.; Gomez Moreno, Henry L.; Reddy, Pavan S.; Goggins, Timothy F.; Mayer, Ingrid A.; Brufsky, Adam M.; Toppmeyer, Deborah L.; Kaklamani, Virginia G.; Atkins, James N.; Berenberg, Jeffrey L.; Sledge, George W. (Massachusetts Medical Society, 2015-11)

  BACKGROUND Prior studies with the use of a prospective–retrospective design including archival tumor samples have shown that gene-expression assays provide clinically useful prognostic information. However, a prospectively ...
• Surgical Excision Without Radiation for Ductal Carcinoma in Situ of the Breast: 12-Year Results From the ECOG-ACRIN E5194 Study 

  Solin, Lawrence J.; Gray, Robert; Hughes, Lorie L.; Wood, William C.; Lowen, Mary Ann; Badve, Sunil S.; Baehner, Frederick L.; Ingle, James N.; Perez, Edith A.; Recht, Abram; Sparano, Joseph A.; Davidson, Nancy E. (American Society of Clinical Oncology, 2015)

  Purpose To determine the 12-year risk of developing an ipsilateral breast event (IBE) for women with ductal carcinoma in situ (DCIS) of the breast treated with surgical excision (lumpectomy) without radiation. Patients ...
• Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration 

  Leung, Samuel C. Y.; Nielsen, Torsten O.; Zabaglo, Lila; Arun, Indu; Badve, Sunil S.; Bane, Anita L.; Bartlett, John M. S.; Borgquist, Signe; Chang, Martin C.; Dodson, Andrew; Enos, Rebecca A.; Fineberg, Susan; Focke, Cornelia M.; Gao, Dongxia; Gown, Allen M.; Grabau, Dorthe; Gutierrez, Carolina; Hugh, Judith C.; Kos, Zuzana; Lænkholm, Anne-Vibeke; Lin, Ming-Gang; Mastropasqua, Mauro G.; Moriya, Takuya; Nofech-Mozes, Sharon; Osborne, C. Kent; Penault-Llorca, Frédérique M.; Piper, Tammy; Sakatani, Takashi; Salgado, Roberto; Starczynski, Jane; Viale, Giuseppe; Hayes, Daniel F.; McShane, Lisa M.; Dowsett, Mitch (Nature, 2016)

  Pathological analysis of the nuclear proliferation biomarker Ki67 has multiple potential roles in breast and other cancers. However, clinical utility of the immunohistochemical (IHC) assay for Ki67 immunohistochemistry has ...
• Association of Stromal Tumor-Infiltrating Lymphocytes With Recurrence-Free Survival in the N9831 Adjuvant Trial in Patients With Early-Stage HER2-Positive Breast Cancer 

  Perez, Edith A.; Ballman, Karla V.; Tenner, Kathy S.; Thompson, E. Aubrey; Badve, Sunil S.; Bailey, Helen; Baehner, Frederick L. (AMA, 2016-01)

  Importance The presence of tumor-infiltrating lymphocytes at diagnosis is reported to be prognostic in triple-negative breast cancer. Objective To evaluate the association of stromal tumor-infiltrating lymphocytes ...
• Low diagnostic yield of transduodenal endoscopic ultrasound-guided fine needle biopsy using the 19-gauge Flex needle: A large multicenter prospective study 

  Attili, Fabia; Fabbri, Carlo; Yasuda, Ichiro; Fuccio, Lorenzo; Palazzo, Laurent; Tarantino, Ilaria; Dewitt, John; Frazzoni, Leonardo; Rimbaş, Mihai; Larghi, Alberto (Medknow Publications, 2017)

  Background and Objectives: Previous limited experiences have reported the 19-gauge flexible needle to be highly effective in performing endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for transduodenal lesions. ...
• Upregulation of HSF1 in estrogen receptor positive breast cancer 

  Gökmen-Polar, Yesim; Badve, Sunil S. (Impact, 2016)

  Heat shock transcription factor 1 (HSF1), a key regulator of the heat-shock response, is deregulated in many cancers. HSF1 can mediate cancer cell survival and metastasis. High levels of HSF1 have been associated with poor ...
• Confocal Endomicroscopy Characteristics of Different Intraductal Papillary Mucinous Neoplasm Subtypes 

  Kamboj, Amrit K; Dewitt, John M; Modi, Rohan M; Conwell, Darwin L; Krishna, Somashekar G (2017-05)

  Intraductal papillary mucinous neoplasms are classified into gastric, intestinal, pancreatobiliary, and oncocytic subtypes where morphology portends disease prognosis. The study aim was to demonstrate EUS-guided needle-based ...
• In utero exposure to HIV and/or antiretroviral therapy: a systematic review of preclinical and clinical evidence of cognitive outcomes 

  McHenry, Megan S.; Balogun, Kayode A.; McDonald, Brenna C.; Vreeman, Rachel C.; Whipple, Elizabeth C.; Serghides, Lena (Wiley, 2019)

  Introducion With the increasing number of children exposed to HIV or antiretroviral therapy in utero, there are concerns that this population may have worse neurodevelopmental outcomes compared to those who are unexposed. ...
• One-Year Analysis of the Prospective Multicenter SENTRY Clinical Trial: Safety and Effectiveness of the Novate Sentry Bioconvertible Inferior Vena Cava Filter 

  Dake, Michael D.; Murphy, Timothy P.; Krämer, Albrecht H.; Darcy, Michael D.; Sewall, Luke E.; Curi, Michael A.; Johnson, Matthew S.; Arena, Frank; Swischuk, James L.; Ansel, Gary M.; Silver, Mitchell J.; Saddekni, Souheil; Brower, Jayson S.; Mendes, Robert; Dake, Michael D.; Feezor, Robert; Kalva, Sanjeeva; Kies, Darren; Bosiers, Marc; Ziegler, Werner; Farber, Mark; Paolini, David; Spillane, Robert; Jones, Steven; Peeters, Patrick (Elsevier, 2018-10-01)

  Purpose To prospectively assess the Sentry bioconvertible inferior vena cava (IVC) filter in patients requiring temporary protection against pulmonary embolism (PE). Materials and Methods At 23 sites, 129 patients with ...
• A systematic review of psychosocial interventions for colorectal cancer patients 

  Mosher, Catherine E.; Winger, Joseph G.; Given, Barbara A.; Shahda, Safi; Helft, Paul R. (SpringerLink, 2017-07)

  PURPOSE: A significant minority of colorectal cancer (CRC) patients experience clinically meaningful distress that may warrant intervention. The goal of this systematic review was to assess the impact of psychosocial ...

View more