• Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease 

  Sohn, Dongwha; Shpanskaya, Katie; Lucas, Joseph E.; Petrella, Jeffrey R.; Saykin, Andrew J.; Tanzi, Rudolph E.; Samatova, Nagiza F.; Doraiswamy, P. Murali (Nature Publishing Group, 2018-05-10)

  Sex differences in Alzheimer's disease (AD) biology and progression are not yet fully characterized. The goal of this study is to examine the effect of sex on cognitive progression in subjects with high likelihood of mild ...
• Delayed and progressive damages to juvenile mice after moderate traumatic brain injury 

  Zhao, Shu; Wang, Xiaoting; Gao, Xiang; Chen, Jinhui (Nature Publishing Group, 2018-05-09)

  Symptoms are commonly more severe in pediatric traumatic brain injury (TBI) patients than in young adult TBI patients. To understand the mechanism, juvenile mice received a controlled cortical impact (CCI) injury at moderate ...
• Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure 

  Visconti, Alessia; Duffy, David L.; Liu, Fan; Zhu, Gu; Wu, Wenting; Chen, Yan; Hysi, Pirro G.; Zeng, Changqing; Sanna, Marianna; Iles, Mark M.; Kanetsky, Peter A.; Demenais, Florence; Hamer, Merel A.; Uitterlinden, Andre G.; Ikram, M. Arfan; Nijsten, Tamar; Martin, Nicholas G.; Kayser, Manfred; Spector, Tim D.; Han, Jiali; Bataille, Veronique; Falchi, Mario (Nature Publishing Group, 2018-05-08)

  The skin's tendency to sunburn rather than tan is a major risk factor for skin cancer. Here we report a large genome-wide association study of ease of skin tanning in 176,678 subjects of European ancestry. We identify ...
• Three challenges for future research on cochlear implants 

  Pisoni, David B.; Kronenberger, William G.; Harris, Michael S.; Moberly, Aaron C. (Elsevier, 2018-01-02)

  Cochlear implants (CIs) often work very well for many children and adults with profound sensorineural (SNHL) hearing loss. Unfortunately, while many CI patients display substantial benefits in recognizing speech and ...
• Overcoming Ovarian Cancer Drug Resistance with a Cold Responsive Nanomaterial 

  Wang, Hai; Agarwal, Pranay; Zhao, Gang; Ji, Guang; Jewell, Christopher M.; Fisher, John P.; Lu, Xiongbin; He, Xiaoming (American Chemical Society, 2018-05-23)

  Drug resistance due to overexpression of membrane transporters in cancer cells and the existence of cancer stem cells (CSCs) is a major hurdle to effective and safe cancer chemotherapy. Nanoparticles have been explored to ...
• Research Needs for Effective Transition in Lifelong Care of Congenital Genitourinary Conditions: A Workshop Sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases 

  Hsieh, Michael; Wood, Hadley M.; Dicianno, Brad E.; Dosa, Nienke P.; Gomez-Lobo, Veronica; Mattoo, Tej K.; Misseri, Rosalia; Norton, Jenna M.; Sawin, Kathleen J.; Scal, Peter; Wright, James E.; Star, Robert A.; Bavendam, Tamara (Elsevier, 2017-05)

  Over the last 5 decades, health-care advances have yielded quantum improvements in the life expectancy of individuals with congenital genitourinary conditions (CGCs), leading to a crisis of care. Many individuals with CGC ...
• Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease 

  Furney, SJ; Simmons, A.; Breen, G.; Pedroso, I.; Lunnon, K.; Proitsi, P.; Hodges, A.; Powell, J.; Wahlund, L-O; Kloszewska, I.; Mecocci, P.; Soininen, H.; Tsolaki, M.; Vellas, B.; Spenger, C.; Lathrop, M.; Shen, L.; Kim, S.; Saykin, AJ; Weiner, MW; Lovestone, S.; Alzheimer's Disease Neuroimaging Initiative and the AddNeuroMed Consortium (Nature Publishing Group, 2011-11)

  Alzheimer's disease (AD) is a progressive neurodegenerative disorder with considerable evidence suggesting an initiation of disease in the entorhinal cortex and hippocampus and spreading thereafter to the rest of the brain. ...
• Cochlear implantation in infants below 12 months of age 

  Miyamoto, Richard T.; Colson, Bethany; Henning, Shirley; Pisoni, David (Elsevier, 2018-02-03)

  To provide safety and efficacy data on infants implanted below 12 months of age. Methods: With the wide application of newborn hearing screening programs, infants with deafness are being identified at birth. When a ...
• 12 guiding premises of pediatric cochlear implant habilitation 

  Robbins, Amy McConkey (ScienceDirect, 2018-02-28)
• Introduction 

  Miyamoto, Richard T. (ScienceDirect, 2017-12)
• Cardiovascular consequences of metabolic syndrome 

  Tune, Johnathan D.; Goodwill, Adam G.; Sassoon, Daniel J.; Mather, Kieren J. (Elsevier, 2017-05)

  The metabolic syndrome (MetS) is defined as the concurrence of obesity-associated cardiovascular risk factors including abdominal obesity, impaired glucose tolerance, hypertriglyceridemia, decreased HDL cholesterol, and/or ...
• Towards broadening Forensic DNA Phenotyping beyond pigmentation: Improving the prediction of head hair shape from DNA 

  Pośpiech, Ewelina; Chen, Yan; Kukla-Bartoszek, Magdalena; Breslin, Krystal; Aliferi, Anastasia; Andersen, Jeppe D.; Ballard, David; Chaitanya, Lakshmi; Freire-Aradas, Ana; van der Gaag, Kristiaan J.; Girón-Santamaría, Lorena; Gross, Theresa E.; Gysi, Mario; Huber, Gabriela; Mosquera-Miguel, Ana; Muralidharan, Charanya; Skowron, Malgorzata; Carracedo, Ángel; Haas, Cordula; Morling, Niels; Parson, Walther; Phillips, Christopher; Schneider, Peter M.; Sijen, Titia; Syndercombe-Court, Denise; Vennemann, Marielle; Wu, Sijie; Xu, Shuhua; Jin, Li; Wang, Sijia; Zhu, Ghu; Martin, Nick G.; Medland, Sarah E.; Branicki, Wojciech; Walsh, Susan; Liu, Fan; Kayser, Manfred (Elsevier, 2018-11)

  Human head hair shape, commonly classified as straight, wavy, curly or frizzy, is an attractive target for Forensic DNA Phenotyping and other applications of human appearance prediction from DNA such as in paleogenetics. ...
• Class I histone deacetylases in retinal progenitors and differentiating ganglion cells 

  Saha, Ankita; Tiwari, Sarika; Dharmarajan, Subramanian; Otteson, Deborah C.; Belecky-Adams, Teri L. (Elsevier, 2018-12)

  Background The acetylation state of histones has been used as an indicator of the developmental state of progenitor and differentiating cells. The goal of this study was to determine the nuclear localization patterns of ...
• Factors associated with human papillomavirus (HPV) test acceptability in primary screening for cervical cancer: A mixed methods research synthesis 

  Tatar, Ovidiu; Thompson, Erika; Naz, Anila; Perez, Samara; Shapiro, Gilla K.; Wade, Kristina; Zimet, Gregory D.; Gilca, Vladimir; Janda, Monika; Kahn, Jessica; Daley, Ellen; Rosberger, Zeev (Elsevier, 2018)

  Primary screening for cervical cancer is transitioning from the longstanding Pap smear towards implementation of an HPV-DNA test, which is more sensitive than Pap cytology in detecting high-risk lesions and offers greater ...
• The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement 

  Weiner, Michael W.; Veitch, Dallas P.; Aisen, Paul S.; Beckett, Laurel A.; Cairns, Nigel J.; Green, Robert C.; Harvey, Danielle; Jack, Clifford R., Jr.; Jagust, William; Morris, John C.; Petersen, Ronald C.; Salazar, Jennifer; Saykin, Andrew J.; Shaw, Leslie M.; Toga, Arthur W.; Trojanowski, John Q. (Elsevier, 2017-05)

  INTRODUCTION: The overall goal of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI-3, which began on August 1, 2016, is a 5-year renewal ...
• On the Gaudin model of type G2 

  Lu, Kang; Mukhin, Evgeny (World Scientific, 2018)

  We derive a number of results related to the Gaudin model associated to the simple Lie algebra of type G2. We compute explicit formulas for solutions of the Bethe ansatz equations associated to the tensor product of an ...
• Communicating with providers about racial healthcare disparities: The role of providers’ prior beliefs on their receptivity to different narrative frames 

  Burgess, Diana J.; Bokhour, Barbara G.; Cunningham, Brooke A.; Do, Tam; Eliacin, Johanne; Gordon, Howard S.; Gravely, Amy; Jones, Dina M.; Partin, Melissa R.; Pope, Charlene; Saha, Somnath; Taylor, Brent C.; Gollust, Sarah E. (Elsevier, 2018)

  Objective Evaluate narratives aimed at motivating providers with different pre-existing beliefs to address racial healthcare disparities. Methods Survey experiment with 280 providers. Providers were classified as high ...
• Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34+ circulating angiogenic cells isolated from diabetic individuals is associated with dysfunctional retinal vasculature and vascular repair process in diabetes 

  Kady, Nermin; Yan, Yuanqing; Salazar, Tatiana; Wang, Qi; Chakravarthy, Harshini; Huang, Chao; Beli, Eleni; Navitskaya, Svetlana; Grant, Maria; Busik, Julia (Elsevier, 2017-05)

  BACKGROUND: Diabetic retinopathy is a microvascular disease that results from retinal vascular degeneration and defective repair due to diabetes-induced endothelial progenitor dysfunction. OBJECTIVE: Understanding ...
• Stereocilia morphogenesis and maintenance through regulation of actin stability 

  McGrath, Jamis; Roy, Pallabi; Perrin, Benjamin J. (Elsevier, 2017-05)

  Stereocilia are actin-based protrusions on auditory and vestibular sensory cells that are required for hearing and balance. They convert physical force from sound, head movement or gravity into an electrical signal, a ...
• Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects 

  Loots, Gabriela G.; Robling, Alexander G.; Chang, Jiun C.; Murugesh, Deepa K.; Bajwa, Jamila; Carlisle, Cameron; Manilay, Jennifer O.; Wong, Alice; Yellowley, Clare E.; Genetos, Damian C. (Elsevier, 2018)

  Tissue oxygen (O2) levels vary during development and disease; adaptations to decreased O2 (hypoxia) are mediated by hypoxia-inducible factor (HIF) transcription factors. HIFs are active in the skeleton, and stabilizing ...

View more