• Are Pain Management Questions in Patient Satisfaction Surveys Driving the Opioid Epidemic? 

  Adams, Jerome; Bledsoe, Gregory H.; Armstrong, John H. (American Public Health Association, 2016-06)
• Effector T Helper Cell Subsets in Inflammatory Bowel Diseases 

  Imam, Tanbeena; Park, Sungtae; Kaplan, Mark H.; Olson, Matthew R. (Frontiers Media, 2018-06-01)

  The gastrointestinal tract is a site of high immune challenge, as it must maintain a delicate balance between tolerating luminal contents and generating an immune response toward pathogens. CD4+ T cells are key in mediating ...
• Exploring Small Extracellular Vesicles for Precision Medicine in Prostate Cancer 

  Giulietti, Matteo; Santoni, Matteo; Cimadamore, Alessia; Carrozza, Francesco; Piva, Francesco; Cheng, Liang; Lopez-Beltran, Antonio; Scarpelli, Marina; Battelli, Nicola; Montironi, Rodolfo (Frontiers Media, 2018-06-13)

  Tumor microenvironment constitutes a complex network in which tumor cells communicate among them and with stromal and immune cells. It has been shown that cancer cells are able to exchange genetic materials through small ...
• Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice 

  Pettit, Ashley P.; Jonsson, William O.; Bargoud, Albert R.; Mirek, Emily T.; Peelor, Frederick F., III; Wang, Yongping; Gettys, Thomas W.; Kimball, Scot R.; Miller, Benjamin F.; Hamilton, Karyn L.; Wek, Ronald C.; Anthony, Tracy G. (Oxford University Press, 2017-06)

  Background: The phosphorylation of eukaryotic initiation factor 2 (p-eIF2) during dietary amino acid insufficiency reduces protein synthesis and alters gene expression via the integrated stress response (ISR).Objective: ...
• Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis 

  Tully, Melissa; Tang, Jonathan; Zheng, Lingxing; Acosta, Glen; Tian, Ran; Hayward, Lee; Race, Nicholas; Mattson, David; Shi, Riyi (Frontiers Media, 2018-06-15)

  Demyelination and axonal injury are the key pathological processes in multiple sclerosis (MS), driven by inflammation and oxidative stress. Acrolein, a byproduct and instigator of oxidative stress, has been demonstrated ...
• Immunotherapy in renal cell carcinoma: latest evidence and clinical implications 

  Santoni, Matteo; Massari, Francesco; Di Nunno, Vincenzo; Conti, Alessandro; Cimadamore, Alessia; Scarpelli, Marina; Montironi, Rodolfo; Cheng, Liang; Battelli, Nicola; Lopez-Beltran, Antonio (Just Medical Media, 2018-06-05)

  Advances in understanding the mechanisms of tumour-induced immunosuppression have led to the development of immune-checkpoint inhibitors in cancer patients, including those with renal cell carcinoma (RCC). The optimal ...
• PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites 

  Ipe, Joseph; Collins, Kimberly S.; Hao, Yangyang; Gao, Hongyu; Bhatia, Puja; Gaedigk, Andrea; Liu, Yunlong; Skaar, Todd C. (Frontiers Media, 2018-06-15)

  Next-generation sequencing (NGS) studies have identified large numbers of genetic variants that are predicted to alter miRNA-mRNA interactions. We developed a novel high-throughput bioassay, PASSPORT-seq, that can functionally ...
• Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production 

  Olson, Matthew R.; Ulrich, Benjamin J.; Hummel, Sarah A.; Khan, Ibrahim; Meuris, Brice; Cherukur, Yesesri; Dent, Alexander L.; Janga, Sarath Chandra; Kaplan, Mark H. (American Association of Immunologists, 2017-06-01)

  IL-2 is a pleiotropic cytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but it impairs the development of Th17 and T follicular helper cells. Although IL-2 is produced by all ...
• Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer's disease 

  Lee, Younghee; Han, Seonggyun; Kim, Dongwook; Kim, Dokyoon; Horgousluoglu, Emrin; Risacher, Shannon L.; Saykin, Andrew J.; Nho, Kwangsik; Alzheimer’s Disease Neuroimaging Initiative (American Medical Informatics Association, 2018-05-18)

  Genetic variation in cis-regulatory elements related to splicing machinery and splicing regulatory elements (SREs) results in exon skipping and undesired protein products. We developed a splicing decision model to identify ...
• Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017 

  Neyman, Anna; Eugster, Erica A. (Y S Medical Media Ltd, 2017-12)

  The most common endocrinopathy associated with McCune-Albright Syndrome (MAS) is peripheral precocious puberty (PP) which occurs far more often in girls than in boys. We will discuss the latest advancements in the treatment ...
• Buccal mucosal graft urethroplasty in the treatment of urethral strictures: experience using the two-surgeon technique 

  Arlen, Angela M.; Powell, Charles R.; Hoffman, Henry T.; Kreder, Karl J. (Hindawi Publishing Corporation, 2010-01-08)

  At our institution, the majority of buccal mucosal graft urethroplasties are performed using a two-team approach with an otolaryngologic surgeon. We report our two-surgeon experience with buccal mucosal grafting for ...
• Targeted tissue engineering: hydrogels with linear capillary channels for axonal regeneration after spinal cord injury 

  Liu, Shengwen; Blesch, Armin (Medknow Publications, 2018-04)

  Spinal cord injury (SCI) frequently results in the permanent loss of function below the level of injury due to the failure of axonal regeneration in the adult mammalian central nervous system (CNS). The limited intrinsic ...
• Prader-Willi syndrome: are there population differences? 

  Butler, Merlin G.; Weaver, David D.; Meaney, F. John (Wiley, 1982-11)

  A 15 1/2-year-old black female with features consistent with the Prader-Willi syndrome is reported. This is the second case report of a black individual and the first case of a black female with the Prader-Willi syndrome. ...
• Implementation of a point-of-care ultrasound skills practicum for hospitalists 

  Cochard, Emily; Fulkerson, Zachary; Carlos, W. Graham (Sage, 2019-02)

  Introduction Point-of-care ultrasound is recognized as a safe and valuable diagnostic tool for patient evaluation. Hospitalists are prime candidates for advancing the point-of-care ultrasound field given their crucial ...
• A novel streamlined trauma response team training improves imaging efficiency for pediatric blunt abdominal trauma patients 

  Nti, Benjamin K.; Laniewicz, Megan; Skaggs, Tracy; Cross, Keith; Fallat, Mary E.; Rominger, Annie (Elsevier, 2019)

  Background/purpose The morbidity and mortality of children with traumatic injuries are directly related to the time to definitive management of their injuries. Imaging studies are used in the trauma evaluation to determine ...
• Brainstem metastases treated with Gamma Knife stereotactic radiosurgery: the Indiana University Health experience 

  Patel, Ajay; Mohammadi, Homan; Dong, Tuo; Shiue, Kevin Ren-Yeh; Frye, Douglas; Le, Yi; Ansari, Shaheryar; Watson, Gordon A.; Miller, James C.; Lautenschlaeger, Tim (Future Medicine:, 2018-01)

  Brainstem metastases offer a unique challenge in cancer treatment, yet stereotactic radiosurgery (SRS) has proven to be an effective modality in treating these tumors. This report discusses the clinical outcomes of patients ...
• Feasibility of Implementing Community Partnerships to Provide Diabetes Prevention Services to Youth 

  Pike, Julie M.; Yazel-Smith, Lisa; Haberlin, Kathryn M.; Hannon, Tamara S. (Springer, 2019-02)

  Type 2 diabetes (T2D) in youth has increased as a result of the obesity epidemic. Diabetes prevention programming is needed for youth, at risk for T2D, and their families. However, there is a lack of diabetes prevention ...
• Product formulas for the 5-division points on the Tate normal form and the Rogers–Ramanujan continued fraction 

  Morton, Patrick (Elsevier, 2019)

  Explicit formulas are proved for the 5-torsion points on the Tate normal form E5 of an elliptic curve having (X,Y)=(0,0) as a point of order 5. These formulas express the coordinates of points in E5[5]−⟨(0,0)⟩ as products ...
• Industry Advisory Board Assessment and Evaluation 

  McIntyre, Charles; Fox, Patricia (ASEE, 2017-02)

  Virtually all academic programs in any given discipline have an Industry Advisory Board (IAB) whose purpose is to add value to the academic program. It must be noted that the term “IAB” is generic in nature and refers to ...
• Posterior stabilized designs in modern total knee arthroplasty: Vestigial organs 

  Stefl, Michael; Meneghini, R. Michael (Elsevier, 2019)

  Clinical difference between posterior-stabilized (PS) and cruciate-retaining (CR) designs in total knee arthroplasty has remained elusive for decades. This classic debate has been given pause due to futile efforts to prove ...

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