ScholarWorks shares over 30,000 articles, working papers, chapters, presentations, posters, theses, historical documents and other items submitted by members of the IUPUI campus community.
Get started! Login with your IU credentials to share freely with 2 million readers per year.
Communities in ScholarWorks
Select a community to browse its collections.
- Scholarship from the Division of Diversity, Equity and Inclusion as well as IUPUI authored or connected scholarship about diversity.
Recent Submissions
2022 Indiana's Physician Assistant Workforce Demand Brief
(Bowen Center for Health Workforce Research and Policy, 2024-04-26) Bowen Center for Health Workforce Research and Policy
Monitoring Indiana's 2022 Physician Assistant Workforce: Supply and Demand.
Learning Outcomes Assessment via Electronic Portfolios
(Emerald Group, 2012) Applegate, Rachel; Irwin, Marilyn M.
Accreditation agencies both institutional and professional (such as the American Library Association) have asked educators to demonstrate student learning outcomes for every academic program that they are assessing, and that they use the data gathered for continuous improvement of programs. This chapter reports on the development of an electronic portfolio (ePortfolio) structure for accomplishing an assessment process within a school of library and information science. From the student side, the portfolio prompts them to select work that they feel is their best effort for each program outcome such as “assist and educate users.” From the faculty side, all items for a given outcome can be downloaded and assessed quantitatively and qualitatively so as to arrive at an understanding of how well the program as a whole is doing, with sufficient detail to guide specific improvement decisions. During design, researchers employed a sequential qualitative feedback system to pose tasks (usability testing) and gather commentaries (through interviews) from students while faculty debated the efficacy of this approach and its place within the school's curricular structure. The local end product was a usable portfolio system implemented within a course management system (Oncourse/Sakai). The generalizable outcome is an understanding of key elements necessary for ePortfolios to function as a program-level assessment system: a place for students to select and store artifacts, a way for faculty to access and review the artifacts, simple aggregations of scoring and qualitative information, and a feedback loop of results into program design for improved student learning.
Use of Co-Development and Testing to Culturally Tailor an Internet- Based Cognitive Behavioral Therapy Intervention through Delivery of Guided Support by Peers
(2024-04-26) Connors, Jill Nault; Magalhaes, Ernani; Prather, Kevin; Khan, Nida; Draucker, Claire; Eliacin, Johanne; Montgomery, Chet; Hayden, Julie; Millard, Michael; Musey, Paul
Sexual Communication Self-Efficacy and PrEP Literacy Helps to Meet HIV Prevention Outcomes Among Black and Latinx Individuals
(Sage Journals, 2022) Carter, Gregory; Brown, Lucy; Mahnke, Brianna; Ohmit, Anita; Woodward, Brennan
Background: Ending the HIV Epidemic is a campaign dedicated to reducing new HIV infections in the United States by 90% by 2030. Preexposure prophylaxis (PrEP) holds significant promise as a prevention tool. However, uptake has not improved much since then. As a result, this research looked at how PrEP literacy relates to sexual communication self-efficacy.
Methods: Between August 4 and 21, 2020, we performed a community-informed cross-sectional study of Black and Latino residents in Indiana. We collected demographic information as well as PrEP literacy, sexual communication self-efficacy, and awareness of HIV status.
Results: Being unaware of one's own HIV status and being unsure of one's sexual identity were both linked to reduced self-efficacy in the domain of sex communication. Those who had a greater level of PrEP literacy felt more confident in their ability to communicate with others about sexually related topics. People living in rural areas showed a significantly lower degree of sexual communication self-efficacy than participants in urban settings.
Conclusion: Providing information about PrEP to those at risk of acquiring the virus may help them connect with treatment or prevention services. Healthcare professionals should take the time to understand their patients' levels of PrEP literacy and communication self-efficacy regarding sexual health.
Osteoclast-mediated bone loss observed in a COVID-19 mouse model
(2021-10-02) Awosanya, Olatundun D.; Dalloul, Christopher E.; Blosser, Rachel J.; Dadwal, Ushashi C.; Carozza, Mariel; Boschen, Karen; Klemsz, Michael J.; Johnston, Nancy A.; Bruzzaniti, Angela; Robinson, Christopher M.; Srour, Edward F.; Kacena, Melissa A.
The consequences of SARS-CoV-2 infection on the musculoskeletal system represent a dangerous knowledge gap. Aging patients are at added risk for SARS-CoV-2 infection; therefore, a greater understanding of the resulting musculoskeletal sequelae of SARS-CoV-2 infection may help guide clinical strategies. This study examined fundamental bone parameters among mice treated with escalating viral loads. Male C57BL/6J (WT, n = 17) and B6.Cg-Tg(K18-ACE2)2Prlmn/J mice (K18-hACE2 transgenic mice, n = 21) expressing human ACE2 (TG) were divided into eight groups (n = 4-6/group) and subjected to intranasal dosing of 0, 1 × 103, 1 × 104, and 1 × 105 PFU (plaque forming units) of human SARS-CoV-2. Animal health was assessed daily by veterinary staff using established and validated scoring criteria (activity, posture, body condition scores and body weight). We report here that mock and WT infected mice were healthy and completed the study, surviving until 12-14 days post infection (dpi). In contrast, the TG mice infected with 1 × 105 PFU all experienced severe health declines that necessitated early euthanasia (6-7 dpi). For TG mice infected with 1 × 104 PFU, 2 mice were also euthanized after 7 dpi, while 3 mice showed signs of moderate disease at day 6 dpi, but recovered fully by day 11 dpi. Four of the 5 TG mice that were infected with 1 × 103 PFU remained healthy throughout the study. This suggests that our study mimics what is seen during human disease, where some patients develop severe disease resulting in death, while others have moderate to severe disease but recover, and others are asymptomatic. At necropsy, femurs were extracted and analyzed by μCT. No difference was found in μCT determined bone parameters among the WT groups. There was, however, a significant 24.4% decrease in trabecular bone volume fraction (p = 0.0009), 19.0% decrease in trabecular number (p = 0.004), 6.2% decrease in trabecular thickness (p = 0.04), and a 9.8% increase in trabecular separation (p = 0.04) among surviving TG mice receiving any viral load compared to non-infected controls. No differences in cortical bone parameters were detected. TRAP staining revealed surviving infected mice had a significant 64% increase in osteoclast number, a 27% increase in osteoclast surface, and a 38% increase in osteoclasts per bone surface. While more studies are needed to investigate the long-term consequences of SARS-CoV-2 infection on skeletal health, this study demonstrates a significant reduction in several bone parameters and corresponding robust increases in osteoclast number observed within 2 weeks post-infection in surviving asymptomatic and moderately affected mice.