IUPUIScholarWorks: Recent submissions

  • Gangaiah, Dharanesh; Raterman, Erica L.; Wu, Hong; Fortney, Kate R.; Gao, Hongyu; Liu, Yunlong; Jerse, Ann E.; Spinola, Stanley M. (American Society for Microbiology, 2017-08-18)
    During infection, Neisseria gonorrhoeae senses and responds to stress; such responses may be modulated by MisRS (NGO0177 and NGO0176), a two-component system that is a homolog of CpxRA. In Escherichia coli, CpxRA senses ...
  • Ramsden, Christopher E.; Domenichiello, Anthony F.; Yuan, Zhi-Xin; Sapio, Matthew R.; Keyes, Gregory S.; Mishra, Santosh K.; Gross, Jacklyn R.; Majchrzak-Hong, Sharon; Zamora, Daisy; Horowitz, Mark S.; Davis, John M.; Sorokin, Alexander V.; Dey, Amit; LaPaglia, Danielle M.; Wheeler, Joshua J.; Vasko, Michael R.; Mehta, Nehal N.; Mannes, Andrew J.; Iadarola, Michael J. (American Association for the Advancement of Science, 2017-08-22)
    Chronic pain and itch are common hypersensitivity syndromes that are affected by endogenous mediators. We applied a systems-based, translational approach to predict, discover, and characterize mediators of pain and itch ...
  • Johnson, D. E.; Hudmon, A. (Hindawi Publishing Corporation, 2017)
    Calcium/calmodulin-dependent protein kinase II (CaMKII) is highly concentrated in the brain where its activation by the Ca2+ sensor CaM, multivalent structure, and complex autoregulatory features make it an ideal translator ...
  • Khan, Sikandar; Biju, Ashok; Wang, Sophia; Gao, Sujuan; Irfan, Omar; Harrawood, Amanda; Martinez, Stephanie; Brewer, Emily; Perkins, Anthony; Unverzagt, Frederick W.; Lasiter, Sue; Zarzaur, Ben; Rahman, Omar; Boustani, Malaz; Khan, Babar (BioMed Central, 2018-02-07)
    BACKGROUND: Patients admitted to intensive care units (ICU) with acute respiratory failure (ARF) face chronic complications that can impede return to normal daily function. A mobile, collaborative critical care model ...
  • Conroy, Andrea L.; Hawkes, Michael T.; Elphinstone, Robyn; Opoka, Robert O.; Namasopo, Sophie; Miller, Christopher; John, Chandy C.; Kain, Kevin C. (BioMed Central, 2018-02-15)
    BACKGROUND: Chitinase-3-like 1 (CHI3L1) is a glycoprotein elevated in paediatric severe malaria, and an emerging urinary biomarker of acute kidney injury (AKI). Based on the hypothesis that elevated CHI3L1 levels in ...
  • Taylor, Laura M.; McMillan, Pamela J.; Liachko, Nicole F.; Strovas, Timothy J.; Ghetti, Bernardino; Bird, Thomas D.; Keene, C. Dirk; Kraemer, Brian C. (BioMed Central, 2018-02-06)
    BACKGROUND: Progressive neuron loss in the frontal and temporal lobes of the cerebral cortex typifies frontotemporal lobar degeneration (FTLD). FTLD sub types are classified on the basis of neuronal aggregated protein ...
  • Katsumoto, Atsuko; Miranda, Aline S.; Butovsky, Oleg; Teixeira, Antônio L.; Ransohoff, Richard M.; Lamb, Bruce T. (BioMed Central, 2018-01-30)
    BACKGROUND: Traumatic brain injury (TBI) is a critical public health and socio-economic problem worldwide. A growing body of evidence supports the involvement of inflammatory events in TBI. It has been reported that ...
  • Antonarakis, Emmanuel S.; Tagawa, Scott T.; Galleti, Giuseppe; Worroll, Daniel; Ballman, Karla; Vanhuyse, Marie; Sonpavde, Guru; North, Scott; Albany, Costantine; Tsao, Che-Kai; Stewart, John; Zaher, Atef; Szatrowski, Ted; Zhou, Wei; Gjyrezi, Ada; Tasaki, Shinsuke; Portella, Luigi; Bai, Yang; Lannin, Timothy B.; Suri, Shalu; Gruber, Conor N.; Pratt, Erica D.; Kirby, Brian J.; Eisenberger, Mario A.; Nanus, David M.; Saad, Fred; Giannakakou, Paraskevi; TAXYNERGY Investigators (American Society of Clinical Oncology, 2017-10-01)
    Purpose The TAXYNERGY trial ( ClinicalTrials.gov identifier: NCT01718353) evaluated clinical benefit from early taxane switch and circulating tumor cell (CTC) biomarkers to interrogate mechanisms of sensitivity or resistance ...
  • Fermann, Gregory J.; Levy, Phillip D.; Pang, Peter; Butler, Javed; Ayaz, S. Imran; Char, Douglas; Dunn, Pat; Jenkins, Cathy A.; Kampe, Christy; Khan, Yosef; Kumar, Vijaya A.; Lindenfeld, JoAnn; Liu, Dandan; Miller, Karen; Peacock, W. Frank; Rizk, Samaa; Robichaux, Chad; Rothman, Russell L.; Schrock, Jon; Singer, Adam; Sterling, Sarah A.; Storrow, Alan B.; Walsh, Cheryl; Wilburn, John; Collins, Sean P. (American Heart Association, 2017-02)
    GUIDED-HF (Get With the Guidelines in Emergency Department Patients With Heart Failure) is a multicenter randomized trial of a patient-centered transitional care intervention in patients with acute heart failure (AHF) who ...
  • Eadon, Michael T.; Cheng, Ying-Hua; Hato, Takashi; Benson, Eric A.; Ipe, Joseph; Collins, Kimberly S.; De Luca, Thomas; El-Achkar, Tarek M.; Bacallao, Robert L.; Skaar, Todd C.; Dagher, Pierre C. (Hindawi Publishing Corporation, 2017)
    siRNA stabilized for in vivo applications is filtered and reabsorbed in the renal proximal tubule (PT), reducing mRNA expression transiently. Prior siRNA efforts have successfully prevented upregulation of mRNA in response ...
  • Casali, Brad T.; Reed-Geaghan, Erin G.; Landreth, Gary E. (BioMed Central, 2018-02-15)
    BACKGROUND: Alzheimer's disease (AD) is a highly prevalent neurodegenerative disorder characterized by pathological hallmarks of beta-amyloid plaque deposits, tau pathology, inflammation, and cognitive decline. Treatment ...
  • Yin, Dechun; Hsieh, Yu-Cheng; Tsai, Wei-Chung; Wu, Adonis Zhi-Yang; Jiang, Zhaolei; Chan, Yi-Hsin; Xu, Dongzhu; Yang, Na; Shen, Changyu; Chen, Zhenhui; Lin, Shien-Fong; Chen, Peng-Sheng; Everett, Thomas H., IV (American Heart Association, 2017-02)
    BACKGROUND: Ventricular fibrillation (VF) during heart failure is characterized by stable reentrant spiral waves (rotors). Apamin-sensitive small-conductance calcium-activated potassium currents (IKAS) are heterogeneously ...
  • Rametta, Raffaella (2018)
    The Italian Constitution guarantees the fundamental freedoms of peaceful assembly (art. 17), association (art. 18), religion (art. 19), expression (art. 21), establishment of trade unions (art. 39) and establishment of ...
  • Tandstad, Torgrim; Kollmannsberger, Christian K.; Roth, Bruce J.; Jeldres, Claudio; Gillessen, Silke; Fizazi, Karim; Daneshmand, Siamak; Lowrance, William T.; Hanna, Nasser H.; Albany, Costantine; Foster, Richard; Cedermark, Gabriella Cohn; Feldman, Darren R.; Powles, Thomas; Lewis, Mark A.; Grimison, Peter Scott; Bank, Douglas; Porter, Christopher; Albers, Peter; De Santis, Maria; Srinivas, Sandy; Bosl, George J.; Nichols, Craig R. (American Society of Clinical Oncology, 2017-11-01)
  • Hartay, Eszter (2018)
    The Hungarian legislation ensures the right to everyone to establish and join organizations and communities based on freedom of association. The two traditional legal forms of nonprofit organizations are the association ...
  • Vinnikov, Oleksandr (2018)
    Ukraine is a unitary republic, and the legal procedures for POs incorporation are the same in all its jurisdictions. Associations, religious organizations and endowments that are not legal entities are allowed in Ukraine. ...
  • Marques, Ricardo André Mendonça (2018)
    There is freedom granted by the Constitution of the Portuguese Republic that safeguards fundamental rights and freedoms. Freedom of Association is recognized in Article 46 of the Constitution provided such associations are ...
  • Strečanský, Boris (2018)
    The Constitution of the Slovak Republic guarantees the “right to associate with others in clubs, societies, or other associations” Article 29 (1) of the Consitution of the Slovak Republic, and in general, individuals can ...
  • Arczewska, Magdalena (2018)
    Polish law permits individuals to act collectively through unregistered groups or organizations. Article 12 of the Constitution of the Republic of Poland from 1997 provides that “The Republic of Poland shall ensure freedom ...
  • Panov, Luben (2018)
    The Bulgarian Constitution guarantees freedom of association, and the Law on Legal Entities with Nonprofit Purposes (NGO Law) provides that both Bulgarian and foreign legal entities and individuals with legal capacity can ...