IUPUIScholarWorks: Recent submissions

  • The Butler-Tarkington Neighborhood Association and the Fight Against Residential Segregation in Indianapolis 
    Prebish, Lydia (2021-07)
    The Butler-Tarkington Neighborhood Association (BTNA) is a community group organized in 1956 by a few concerned couples living in the Butler-Tarkington neighborhood on the north side of Indianapolis. These couples, both ...
  • The Impact Of A Growth Measurement Training Program On The Use Of Length Boards In A Newborn Intensive Care Unit. 
    Thornton, Jessica Lynn (2021-07)
    Objective: Nutritional assessment of infants in the Newborn Intensive Care Unit (NICU) depends on the performance of accurate, serial anthropometric measurements. In this Level IV NICU, nurses used tape measures more often ...
  • Serious mental illness and gun-related injury 
    Wiehe, Sarah E.; Magee, Lauren; Gharbi, Sami; Lipscomb, Elaine; Aalsma, Matthew (APHA, 2018-11-13)
  • Violent Injury Recidivism Among Urban Assault Victims: A 10-year Cohort Study 
    Magee, Lauren; Aalsma, Matthew; Gharbi, Sami; Wiehe, Sarah E. (APHA, 2018-11)
  • A Latent Class Analysis of Vaping, Substance Use and Asthma Among U.S. High School Students: Results from the Center for Disease Control's Youth Risk Behavior Survey 
    Zervos, Andrew Peter (2021-07)
    Rates of vaping among high school students have increased significantly over the past decade. Prior research has found significant associations between youth vaping and substance use. However, little is known about how ...
  • Vascular amyloid accumulation alters the gabaergic synapse and induces hyperactivity in a model of cerebral amyloid angiopathy 
    Cisternas, Pablo; Taylor, Xavier; Perkins, Abigail; Maldonado, Orlando; Allman, Elysabeth; Cordova, Ricardo; Marambio, Yamil; Munoz, Braulio; Pennington, Taylor; Xiang, Shunian; Zhang, Jie; Vidal, Ruben; Atwood, Brady; Lasagna-Reeves, Cristian A. (Wiley, 2020-09-10)
    Cerebral amyloid angiopathy (CAA) is typified by the cerebrovascular deposition of amyloid. The mechanisms underlying the contribution of CAA to neurodegeneration are not currently understood. Although CAA is highly ...
  • Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study 
    Patidar, Kavish R.; Garimella, Pranav S.; Macedo, Etienne; Slaven, James E.; Ghabril, Marwan S.; Weber, Regina E.; Anderson, Melissa; Orman, Eric S.; Nephew, Lauren D.; Desai, Archita P.; Chalasani, Naga P.; El-Achkar, Tarek M. (American Physiological Society, 2019-10-01)
    Acute kidney injury (AKI) is a common complication in hospitalized patients with cirrhosis. Uromodulin, a protein uniquely produced by the kidney and released both in the urine and circulation, has been shown to regulate ...
  • BATF-Interacting Proteins Dictate Specificity in Th Subset Activity 
    Fu, Yongyao; Koh, Byunghee; Kuwahara, Makoto; Ulrich, Benjamin J.; Kharwadkar, Rakshin; Yamashita, Masakatsu; Kaplan, Mark H. (American Association of Immunologists, 2020-10-01)
    The basic leucine zipper (bZIP) transcription factor BATF is expressed in multiple Th subsets and cooperates with other factors to regulate gene transcription. BATF activates lineage-specific cytokines in Th subsets, ...
  • Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway 
    Liu, Yunjian; Kim, Hyeong Geug; Dong, Edward; Dong, Chuanpeng; Huang, Menghao; Liu, Yunlong; Liangpunsakul, Suthat; Dong, Xiaocheng Charlie (Elsevier, 2019-10-01)
    Sestrin 3 (Sesn3) belongs to a small protein family that has been implicated in multiple biological processes including anti-oxidative stress, anti-aging, cell signaling, and metabolic homeostasis. However, the role of ...
  • Clickable modular polysaccharide nanoparticles for selective cell-targeting 
    Peuler, Kevin; Dimmitt, Nathan; Lin, Chien-Chi (Elsevier, 2020-04-15)
    A therapeutic nanocarrier capable of cell targeting has the potential to reduce off-target effects of otherwise effective drugs. Nanoparticle surface modification can be tailored for specific cells, however multistep surface ...
  • Differential susceptibility of retinal ganglion cell subtypes in acute and chronic models of injury and disease 
    VanderWall, Kirstin B.; Lu, Bin; Alfaro, Jorge S.; Allsop, Anna R.; Carr, Alexa S.; Wang, Shaomei; Meyer, Jason S. (Nature Publishing Group, 2020-10-15)
    Retinal ganglion cells (RGCs) are a heterogeneous population of neurons, comprised of numerous subtypes that work synchronously to transmit visual information to the brain. In blinding disorders such as glaucoma, RGCs are ...
  • Evaluation of variable flip angle, MOLLI, SASHA, and IR-SNAPSHOT pulse sequences for T1 relaxometry and extracellular volume imaging of the pancreas and liver 
    Tirkes, Temel; Zhao, Xuandong; Lin, Chen; Stuckey, Alex Jordan; Li, Liang; Giri, Shivriman; Nickel, Dominik (Elsevier, 2019-06-04)
    Purpose Compare four T1 mapping pulse sequences for T1 relaxometry and extracellular volume (ECV) fraction of the pancreas and liver Materials and Methods In vitro phase of this prospective study was performed on a ...
  • Oncology clinical trials and insurance coverage: An update in a tenuous insurance landscape 
    Obeng-Gyasi, Samilia; Kircher, Sheetal M.; Lipking, Kelsey P.; Keele, Benjamin J.; Benson, Al B.; Wagner, Lynne I.; Carlos, Ruth C. (Wiley, 2019-06-28)
  • Hepatic steatosis is highly prevalent but is not correlated with stiffness in autoimmune hepatitis 
    Chalasani, Sai; Mathur, Karan; Shammas, Nicole; Orman, Eric; Vuppalanchi, Raj; Lammert, Craig (Wolters Kluwer, 2020-10-16)
    The prevalence and impact of hepatic steatosis among patients with autoimmune hepatitis (AIH) is not well described. We conducted a cross-sectional study to determine the prevalence of hepatic steatosis in AIH patients ...
  • A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation 
    Tran, Tuan M.; Guha, Rajan; Portugal, Silvia; Skinner, Jeff; Ongoiba, Aissata; Bhardwaj, Jyoti; Jones, Marcus; Moebius, Jacqueline; Venepally, Pratap; Doumbo, Safiatou; DeRiso, Elizabeth A.; Li, Shanping; Vijayan, Kamalakannan; Anzick, Sarah L.; Hart, Geoffrey T.; O’Connell, Elise M.; Doumbo, Ogobara K.; Kaushansky, Alexis; Alter, Galit; Felgner, Phillip L.; Lorenzi, Hernan; Kayentao, Kassoum; Traore, Boubacar; Kirkness, Ewen F.; Crompton, Peter D. (Elsevier, 2019-10-15)
    Immunity that controls parasitemia and inflammation during Plasmodium falciparum (Pf) malaria can be acquired with repeated infections. A limited understanding of this complex immune response impedes the development of ...
  • Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS 
    Wu, Xue; Niculite, Cristina M.; Preda, Mihai Bogdan; Rossi, Annalisa; Tebaldi, Toma; Butoi, Elena; White, Mattie K.; Tudoran, Oana M.; Petrusca, Daniela N.; Jannasch, Amber S.; Bone, William P.; Zong, Xingyue; Fang, Fang; Burlacu, Alexandrina; Paulsen, Michelle T.; Hancock, Brad A.; Sandusky, George E.; Mitra, Sumegha; Fishel, Melissa L.; Buechlein, Aaron; Ivan, Cristina; Oikonomopoulos, Spyros; Gorospe, Myriam; Mosley, Amber; Radovich, Milan; Davé, Utpal P.; Ragoussis, Jiannis; Nephew, Kenneth P.; Mari, Bernard; McIntyre, Alan; Konig, Heiko; Ljungman, Mats; Cousminer, Diana L.; Macchi, Paolo; Ivan, Mircea (Nature Publishing Group, 2020-09-21)
    We hereby provide the initial portrait of lincNORS, a spliced lincRNA generated by the MIR193BHG locus, entirely distinct from the previously described miR-193b-365a tandem. While inducible by low O2 in a variety of cells ...
  • Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations 
    Peterson, Roseann E.; Kuchenbaecker, Karoline; Walters, Raymond K.; Chen, Chia-Yen; Popejoy, Alice B.; Periyasamy, Sathish; Lam, Max; Iyegbe, Conrad; Strawbridge, Rona J.; Brick, Leslie; Carey, Caitlin E.; Martin, Alicia R.; Meyers, Jacquelyn L.; Su, Jinni; Chen, Junfang; Edwards, Alexis C.; Kalungi, Allan; Koen, Nastassja; Majara, Lerato; Schwarz, Emanuel; Smoller, Jordan W.; Stahl, Eli A.; Sullivan, Patrick F.; Vassos, Evangelos; Mowry, Bryan; Prieto, Miguel L.; Cuellar-Barboza, Alfredo; Bigdeli, Tim B.; Edenberg, Howard J.; Huang, Hailiang; Duncan, Laramie E. (Elsevier, 2019-10-10)
    Genome-wide association studies (GWAS) have focused primarily on populations of European descent, but it is essential that diverse populations become better represented. Increasing diversity among study participants will ...
  • STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus 
    Fu, Yongyao; Wang, Jocelyn; Panangipalli, Gayathri; Ulrich, Benjamin J.; Koh, Byunghee; Xu, Chengxian; Kharwadkar, Rakshin; Chu, Xiaona; Wang, Yue; Gao, Hongyu; Wu, Wenting; Tepper, Robert S.; Zhou, Baohua; Janga, Sarath Chandra; Yang, Kai; Kaplan, Mark H. (Nature Publishing Group, 2020-09-28)
    T helper cell differentiation requires lineage-defining transcription factors and factors that have shared expression among multiple subsets. BATF is required for development of multiple Th subsets but functions in a ...
  • Biological Hallmarks of Cancer in Alzheimer’s Disease 
    Nudelman, Kelly N. H.; McDonald, Brenna C.; Lahiri, Debomoy K.; Saykin, Andrew J. (Elsevier, 2019-04-16)
    Although Alzheimer’s disease (AD) is an international health research priority for our aging population, little therapeutic progress has been made. This lack of progress may be partially attributable to disease heterogeneity. ...
  • Gastrointestinal complications after kidney transplantation 
    Gioco, Rossella; Corona, Daniela; Ekser, Burcin; Puzzo, Lidia; Inserra, Gaetano; Pinto, Flavia; Schipa, Chiara; Privitera, Francesca; Veroux, Pierfrancesco; Veroux, Massimiliano (Baishideng Publishing Group Inc., 2020-10-14)
    Gastrointestinal complications are common after renal transplantation, and they have a wide clinical spectrum, varying from diarrhoea to post-transplant inflammatory bowel disease (IBD). Chronic immunosuppression may ...