Dermatology Articles

 

Recent Submissions

  • Ni, Jonathan; Gilbert, Kathleen E.; Manalo, Ivie F.; Wu, Jashin J. (Permanente Press, 2017)
    INTRODUCTION: Hailey-Hailey disease is an adult-onset skin condition characterized by lesions in the intertriginous regions of the body. The lesions can be pruritic, painful, and associated with physical and social ...
  • Singh, Natalia N.; Howell, Matthew D.; Androphy, Elliot J.; Singh, Ravindra N. (Nature Publishing group, 2017-09)
    Spinal muscular atrophy (SMA), a prominent genetic disease of infant mortality, is caused by low levels of survival motor neuron (SMN) protein owing to deletions or mutations of the SMN1 gene. SMN2, a nearly identical copy ...
  • Krbanjevic, Aleksandar; Travers, Jeffrey B.; Spandau, Dan F (Springer Verlag, 2016-09)
    As the incidence of non-melanoma skin cancer (NMSC) is increasing, there is a growing need to identify effective preventive strategies. A recently proposed hypothesis states that NMSC photocarcinogenesis is tightly linked ...
  • Loesch, Mathew M.; Collier, Ann E.; Southern, David H.; Ward, Rachel E.; Tholpady, Sunil S.; Lewis, Davina A.; Travers, Jeffrey B.; Spandau, Dan F. (Wiley, 2016-10)
    The activation status of the insulin‐like growth factor‐1 receptor (IGF‐1R) regulates the cellular response of keratinocytes to ultraviolet B (UVB) exposure, both in vitro and in vivo. Geriatric skin is deficient in IGF‐1 ...
  • Greenberg, Sophie A.; Schlosser, Bethanee J.; Mirowski, Ginat W. (Elsevier, 2017-10)
    Heath care providers should be comfortable with normal as well as pathologic findings in the lips, because the lips are highly visible and may display clinical manifestations of local, as well as systemic inflammatory, ...
  • Choi, Sungwoon; Calder, Alyssa N.; Miller, Eliza H.; Anderson, Kierstyn P.; Fiejtek, Dawid K.; Rietz, Anne; Li, Hongxia; Cherry, Jonathan J.; Quist, Kevin M.; Xing, Xuechao; Glicksman, Marcie A.; Cuny, Gregory D.; Lorson, Christian L.; Androphy, Elliot A.; Hodgetts, Kevin J. (Elsevier, 2017-12)
    Spinal muscular atrophy (SMA) is a neurodegenerative disorder that results from mutations in the SMN1 gene, leading to survival motor neuron (SMN) protein deficiency. One therapeutic strategy for SMA is to identify compounds ...
  • Rebello, Sharrel; Jose, Leny; Sindhu, Raveendran; Aneesh, Embalil Mathachan (Springer, 2017-04)
    Since the discovery of phytic acid in 1903 and phytase in 1907, extensive research has been carried out in the field of phytases, the phytic acid degradatory enzymes. Apart from forming backbone enzyme in the multimillion ...
  • Gehlhausen, Jeff R.; Strausburg, Matthew B.; Aouthmany, Mouhammad; Katona, Terrence M.; Turner, Matthew J. (University of California, 2017)
    Capecitabine is a 5-fluorouracil basedchemotherapeutic drug widely used in the treatmentof solid tumors, especially colorectal and breast. Someof the most common side effects of capecitabine arecutaneous in nature, including ...
  • Hirt, Molly B.; Heskett, Jordan; Veerula, Vindhya; Warren, Simon; Avashia-Khemka, Nidhi; Mark, Lawrence A. (Elsevier, 2017-05)
  • Ward, Rachel Elizabeth; Ali, Stefanie Ann; Kuhar, Matthew (Wiley, 2017)
    Malignant mesothelioma (MM) is an aggressive and invasive neoplasm primarily affecting the pleura, peritoneum and pericardium. While mesothelioma commonly metastasizes to visceral organs, it has rarely been documented to ...
  • Calder, Alyssa N.; Androphy, Elliot J.; Hodgetts, Kevin J. (ACS, 2016-08)
    Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease resulting from pathologically low levels of survival motor neuron (SMN) protein. The majority of mRNA from the SMN2 allele undergoes alternative ...
  • Shabeeb, Nadine M.; Plager, David A.; Haggstrom, Anita N. (Elsevier, 2017-08)
    PHACE syndrome is a rare neurocutaneous disorder, with a complex pathogenesis. It presents with a large facial hemangioma associated with anomalies of the posterior fossa of the brain, arterial anomalies, cardiac anomalies, ...
  • Custer, Sara K.; Gilson, Timra D.; Li, Hongxia; Todd, A. Gary; Astroski, Jacob W.; Lin, Hai; Liu, Yunlong; Androphy, Elliot J. (Public Library of Science (PLoS), 2016)
    Spinal muscular atrophy (SMA) is an intractable neurodegenerative disease afflicting 1 in 6-10,000 live births. One of the key functions of the SMN protein is regulation of spliceosome assembly. Reduced levels of the SMN ...
  • Li, Xin; Liu, Hongliang; Amos, Christopher I.; Lee, Jeffrey E.; Thomas, Nancy E.; Wei, Qingyi; Han, Jiali (Wiley, 2017-08)
  • Veerkamp, Patrick; Mousdicas, Nico; Bednarek, Robert (InnoVision Health Media, 2016-12)
    CONTEXT: Rosacea fulminans is a rare skin disorder with a multifactorial etiology. Stress is one of the common precipitating factors of this condition but is not often targeted in treatment. Isotretinoin is considered ...
  • Collier, Ann E.; Wek, Ronald C.; Spandau, Dan F. (Elsevier, 2017)
    Appropriate and sequential differentiation of keratinocytes is essential for all functions of the human epidermis. While transcriptional regulation has proven to be important for keratinocyte differentiation, little is ...
  • Li, Hongxia; Custer, Sara K.; Gilson, Timra; Hao, Le Thi; Beattie, Christine E.; Androphy, Elliot J. (Oxford University Press, 2015-12-20)
    Spinal muscular atrophy (SMA), a heritable neurodegenerative disease, results from insufficient levels of the survival motor neuron (SMN) protein. α-COP binds to SMN, linking the COPI vesicular transport pathway to SMA. ...
  • Sahu, Ravi P.; Harrison, Kathleen A.; Weyerbacher, Jonathan; Murphy, Robert C.; Konger, Raymond L.; Garrett, Joy Elizabeth; Chin-Sinex, Helen Jan; Johnston II., Michael Edward; Dynlacht, Joseph R.; Mendonca, Marc; McMullen, Kevin; Li, Gengxin; Spandau, Dan F.; Travers, Jeffrey B. (Impact Journals, 2016-04-12)
    Pro-oxidative stressors can suppress host immunity due to their ability to generate oxidized lipid agonists of the platelet-activating factor-receptor (PAF-R). As radiation therapy also induces reactive oxygen species, the ...
  • Koyama, Sachiko; Soini, Helena A.; Wager-Miller, James; Alley, William R.; Pizzo, Matthew J.; Rodda, Cathleen; Alberts, Jeffrey; Crystal, Jonathon D.; Lai, Cary; Foley, John; Novotny, Milos V. (The Royal Society, 2015-07-22)
    The current understanding of the activity of mammalian pheromones is that endocrine and behavioural effects are limited to the exposed individuals. Here, we demonstrate that the nasal exposure of female mice to a male ...
  • Sahu, Ravi P.; Ocana, Jesus A.; Harrison, Kathleen A.; Ferracini, Matheus; Touloukian, Christopher E.; Al-Hassani, Mohammed; Sun, Louis; Loesch, Mathew; Murphy, Robert C.; Althouse, Sandra K.; Perkins, Susan M.; Speicher, Paul J.; Tyler, Douglas S.; Konger, Raymond L.; Travers, Jeffrey B. (American Association for Cancer Research, 2014-12-01)
    Oxidative stress suppresses host immunity by generating oxidized lipid agonists of the platelet-activating factor receptor (PAF-R). Because many classical chemotherapeutic drugs induce reactive oxygen species (ROS), we ...

View more