• Pyk2 Regulates Human Papillomavirus Replication by Tyrosine Phosphorylation of the E2 Protein 

  Jose, Leny; DeSmet, Marsha; Androphy, Elliot J. (American Society for Microbiology, 2020-09-29)

  The human papillomavirus (HPV) E2 protein is a key regulator of viral transcription and replication. In this study, we demonstrate that the nonreceptor tyrosine kinase Pyk2 phosphorylates tyrosine 131 in the E2 transactivation ...
• Ex vivo culture of mouse skin activates an interleukin 1 alpha-dependent inflammatory response 

  Zhou, Hong-Ming; Slominski, Radomir M.; Seymour, Leroy J.; Bell, Maria C.; Dave, Priya; Atumonye, Joseph; Wright, William, III.; Dawes, Avery; Griesenauer, Brad; Paczesny, Sophie; Kaplan, Mark H.; Spandau, Dan F.; Turner, Matthew J. (Wiley, 2020-01)

  Ex vivo culture of mouse and human skin causes an inflammatory response characterized by production of multiple cytokines. We used ex vivo culture of mouse tail skin specimens to investigate mechanisms of this skin ...
• Wounding with a Microneedling Device Corrects the Inappropriate Ultraviolet B Radiation Response in Geriatric Ski 

  Travers, Jeffrey B.; Kemp, Michael G.; Weir, Nathan M.; Cates, Elizabeth; Alkawar, Abdulrahman M.; Mahajan, Avinash S.; Spandau, Dan F. (SpringerLink, 2020-01)

  Non-melanoma skin cancer primarily affects geriatric patients as evidenced by the fact that only 20% of these cancers are diagnosed in patients under the age of 60 years. Of importance, geriatric skin responds to procarcinogenic ...
• Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication 

  Jose, Leny; Androphy, Elliot J.; DeSmet, Marsha (American Society for Microbiology, 2020-07)

  The papillomavirus (PV) E2 protein is a critical regulator of viral transcription and genome replication. We previously reported that tyrosine (Y) 138 of HPV-31 E2 is phosphorylated by the fibroblast growth factor receptor ...
• Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance 

  Gilson, Timra; Culleton, Sara; Xie, Fang; DeSmet, Marsha; Androphy, Elliot J. (American Society for Microbiology, 2020-07-30)

  Several serine and threonine residues of the papillomavirus early E2 protein have been found to be phosphorylated. In contrast, only one E2 tyrosine phosphorylation site in BPV-1 (tyrosine 102) and one in HPV-16/31 (tyrosine ...
• Single Ablative Fractional Resurfacing Laser Treatment For Forearm Actinic Keratoses: 6-Month Follow-Up Data From An Intrapatient Comparison Between Treated and Untreated Sites 

  Chen, Roy; Wargo, Jeffrey J.; Williams, Amy; Cates, Elizabeth; Spandau, Dan F.; Knisley, Christina; Travers, Jeffrey B. (Wiley, 2020-01)

  Background and objectives: Actinic keratoses (AK) are common pre-cancerous lesions, which are associated with ultraviolet light exposure and aging. Wounding therapies such as fractionated laser resurfacing (FLR) have been ...
• Short-duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy 

  Rietz, Anne; Hodgetts, Kevin J.; Lusic, Hrvoje; Quist, Kevin M.; Osman, Erkan Y.; Lorson, Christian L.; Androphy, Elliot J. (EMBO Press, 2021-01)

  Spinal muscular atrophy (SMA) is a motor neuron disease and the leading genetic cause of infant mortality. SMA results from insufficient survival motor neuron (SMN) protein due to alternative splicing. Antisense oligonucleotides, ...
• Erythema nodosum treated by sulfasalazine in a pregnant patient 

  Mohammed, Arooj; Rahnama-Moghadam, Sahand (Wiley, 2020-11)
• Apixaban-induced cutaneous hypersensitivity: a case series with evidence of cross-reactivity 

  Isaq, Nasro A.; Vinson, Whitney M.; Rahnama-Moghadam, Sahand (University of California, 2020)
• Pedunculated atypical fibroxanthomas of the face 

  Xiao, Honglin; Bittar, Peter G.; Wolverton, Jay E. (UC Davis, 2020-10)

  Atypical fibroxanthomas are rare, superficial dermal tumors. Most cases are benign and only locally destructive with a low rate of metastasis. Lesions are most commonly found on sun-exposed sites of elderly light-skinned ...
• An Analysis of Public Sunscreen Distribution in the United States During the COVID-19 Pandemic 

  Szeto, Mindy D.; Kokoska, Ryan E.; Maghfour, Jalal; Rundle, Chandler W.; Presley, Colby L.; Harp, Taylor; Hamp, Austin; Wegener, Victoria; Hugh, Jeremy; Dellavalle, Robert P. (Elsevier, 2022)
• Dermatologic manifestations of vascular access steal syndrome 

  Hekman, Daniel; Burton, Kyle; Rahnama-Moghadam, Sahand (Our Dermatology Online, 2020)
• Developing classification criteria for skin-predominant dermatomyositis: the Delphi process 

  Concha, J. S. S.; Pena, S.; Gaffney, R. G.; Patel, B.; Tarazi, M.; Kushner, C. J.; Merola, J. F.; Fiorentino, D.; Dutz, J. P.; Goodfield, M.; Nyberg, F.; Volc-Platzer, B.; Fujimoto, M.; Ang, C. C.; Werth, V. P.; The Skin Myositis Delphi Group (Wiley, 2020-02)

  Background The European League Against Rheumatism/American College of Rheumatology classification criteria for inflammatory myopathies are able to classify patients with skin-predominant dermatomyositis (DM). However, ...
• The safety of rituximab for the treatment of autoimmune blistering diseases: A systematic review 

  Mohammed, Arooj; Hekman, Daniel; Li, Wendy; Misquith, Chelsea; Rahnama-Moghadam, Sahand (Elsevier, 2021)
• Characterization of medical malpractice lawsuits relating to dermatologic emergencies in the inpatient and emergency setting 

  Rumancik, Brad; Keele, Benjamin J.; Rahnama-Moghadam, Sahand (Elsevier, 2020)
• Segmental infantile hemangioma and concomitant hypertension in three African American neonates 

  Kullberg, Sara A.; Rheault, Michelle N.; Haggstrom, Anita; Maguiness, Sheilagh M. (Wiley, 2020-05)

  We present three African American infants with segmental, ulcerated infantile hemangiomas and concomitant, persistent hypertension. When treated with beta-blocker therapy, the hemangiomas decreased in size and the ulcerations ...
• Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk 

  Konger, Raymond L.; Ren, Lu; Sahu, Ravi P.; Derr-Yellin, Ethel; Kim, Young L. (Nature, 2020-11-05)

  With recurring carcinogen exposures, individual tumors develop in a field of genetic mutations through a stepwise process of clonal expansion and evolution. Once established, this “cancer field” persists in the absence of ...
• An unusual presentation of cutaneous histoplasmosis as a recurrent solitary and spontaneously healing lesion in an immunocompetent patient 

  Muldoon, Jessica L.; Wysozan, Timothy R.; Toubin, Yulianna; Relich, Ryan F.; Davis, Thomas E.; Zhang, Chen; Alomari, Ahmed K. (Microbiology Society, 2020)

  Infection with Histoplasma capsulatum typically manifests as a self-limiting pulmonary disease in immunocompetent patients. Systemic symptoms such as cutaneous lesions are associated with immunodeficient states. Our patient ...
• Video visits for isotretinoin patients are perceived as safe, effective, and convenient 

  Hekman, Daniel; Maldonado, Sarina Masso; Wolverton, Jay; Rahnama-Moghadam, Sahand (UC Davis, 2021)
• Systematic Review and Meta-Analysis of Local Recurrence Rates of Head and Neck Cutaneous Melanomas after Wide Local Excision, Mohs Micrographic Surgery, or Staged Excision 

  Bittar, Peter G.; Bittar, Julie M.; Etzkorn, Jeremy R.; Brewer, Jerry D.; Aizman, Leora; Shin, Thuzar M.; Sobanko, Joseph F.; Higgins, Harold W.; Giordano, Cerrene N.; Cohen, Justine V.; Pride, Renee; Wan, Marilyn T.; Leitenberger, Justin J.; Bar, Anna A.; Aasi, Sumaira; Bordeaux, Jeremy S.; Miller, Christopher J. (Science Direct, 2021-09-01)

  Background Prospective trials have not compared local recurrence rates for different excision techniques for cutaneous melanomas on the head and neck. Objective To determine local recurrence rates of cutaneous head and ...

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