• Effects of Proton Center Closure on Pediatric Case Volume and Resident Education at an Academic Cancer Center 

  Galle, James O.; Long, David E.; Lautenschlaeger, Tim; Zellars, Richard C.; Watson, Gordon A.; Ellsworth, Susannah G. (Elsevier, 2018-03)

  Purpose To analyze effects of closure of an academic proton treatment center (PTC) on pediatric case volume, distribution, and resident education. Methods and Materials This was a review of 412 consecutive pediatric ...
• RADIANS: A Multidisciplinary Central Nervous System Clinic Model for Radiation Oncology and Neurosurgery Practice 

  McClelland, Shearwood, III; Mitin, Timur; Jaboin, Jerry J.; Ciporen, Jeremy N. (Elsevier, 2019-02)

  Background Radiation therapy for central nervous system disease commonly involves collaboration between Radiation Oncology and Neurosurgery. We describe our early experience with a multidisciplinary clinic model. Methods In ...
• Toxicity of Radiosurgery for Brainstem Metastases 

  Patel, Ajay; Dong, Tuo; Ansari, Shaheryar; Cohen-Gadol, Aaron; Watson, Gordon; de Moraes, Fabio Ynoe; Nakamura, Masaki; Murovic, Judith; Chang, Steven D.; Hatiboglu, Mustafa Aziz; Chung, Caroline; Miller, James; Lautenschlaeger, Tim (Elsevier, 2018)

  Background Although stereotactic radiosurgery (SRS) is an effective modality in the treatment of brainstem metastases (BSM), radiation-induced toxicity remains a critical concern. To better understand how severe or ...
• Tumor Treating Fields Utilization in a Glioblastoma Patient with a Preexisting Cardiac Pacemaker: The First Reported Case 

  McClelland, Shearwood, III; Henrikson, Charles A.; Ciporen, Jeremy N.; Jaboin, Jerry J.; Mitin, Timur (Elsevier, 2018-11)

  Background Tumor-treating fields (TTFs) have become an important, evidence-based modality in the treatment of glioblastoma (GBM). In patients requiring cardiac pacemakers, TTF therapy is complicated by theoretical concerns ...
• Responses to the 2017 ‘1 Million Gray Question’: ASTRO membership’s opinions on the most important research question facing radiation oncology 

  Dominello, Michael M.; Keen, Judith C.; Beck, Tyler F.; Bayouth, John; Knisely, Jonathan; Carlson, David J.; Mendonca, Marc S.; Mian, Omar; Brock, Kristy K.; Anscher, Mitchell; Hugo, Geoffrey; Moros, Eduardo G.; Singh, Anurag K.; Yu, James B. (Elsevier, 2018-10)

  At the American Society for Radiation Oncology's (ASTRO's) 2017 annual meeting in San Diego, CA, attendees were asked, “What is the most important research question that needs to be answered in the next 3 to 5 years?” This ...
• A quality assurance phantom for electronic portal imaging devices 

  Das, Indra J.; Cao, Minsong; Cheng, Chee-Wai; Misic, Vladimir; Scheuring, Klaus; Schüle, Edmund; Johnstone, Peter A.S. (American Association of Physicists in Medicine, 2011)

  Electronic portal imaging device (EPID) plays an important role in radiation therapy portal imaging, geometric and dosimetric verification. Consistent image quality and stable radiation response is necessary for proper ...
• Histology, Tumor Volume, and Radiation Dose Predict Outcomes in NSCLC Patients After Stereotactic Ablative Radiotherapy 

  Shiue, Kevin; Cerra-Franco, Alberto; Shapiro, Ronald; Estabrook, Neil; Mannina, Edward M.; Deig, Christopher R.; Althouse, Sandra; Liu, Sheng; Wan, Jun; Zang, Yong; Agrawal, Namita; Ioannides, Pericles; Liu, Yongmei; Zhang, Chen; DesRosiers, Colleen; Bartlett, Greg; Ewing, Marvene; Langer, Mark P.; Watson, Gordon; Zellars, Richard; Kong, Feng-Ming; Lautenschlaeger, Tim (Elsevier, 2018)

  Introduction It remains unclear if histology should be independently considered when choosing stereotactic ablative body radiotherapy dose prescriptions for NSCLC. Methods The study population included 508 patients ...
• Superimposition of beams to vary shot size in gamma knife stereotactic radiosurgery 

  Bank, Morris I.; Timmerman, Robert (American Association of Physicists in Medicine, 2002)

  The Leksell Gamma Knife [Elekta Corp] uses helmets as collimators to produce four standard beam sizes. The nominal beam diameters are 18, 14, 8, and 4 mm. During computer treatment planning for gamma knife stereotactic ...
• Comparison of 16 mm OSU-Nag and COMS eye plaques 

  Zhang, Hualin; Davidorf, Frederick; Qi, Yujin (American Association of Physicists in Medicine, 2012-05-10)

  OSU-NAG eye plaques use fewer sources than COMS-plaques of comparable size, and do not employ a Silastic seed carrier insert. Monte Carlo modeling was used to calculate 3D dose distributions for a 16 mm OSU-NAG eye plaque ...
• Impact of proton beam availability on patient treatment schedule in radiation oncology 

  Miller, Eric D.; Derenchuk, Vladimir; Das, Indra J.; Johnstone, Peter A. S. (American Association of Physicists in Medicine, 2012-11-08)

  Proton beam therapy offers unique physical properties with potential for reduced toxicity and better patient care. There is an increased interest in radiation oncology centers to acquire proton therapy capabilities. The ...
• Intra- and intervariability in beam data commissioning among water phantom scanning systems 

  Akino, Yuichi; Gibbons, John P.; Neck, Daniel W.; Chu, Connel; Das, Indra J. (American Association of Physicists in Medicine, 2014-07-08)

  Accurate beam data acquisition during commissioning is essential for modeling the treatment planning system and dose calculation in radiotherapy. Although currently several commercial scanning systems are available, there ...
• Ion chamber measurements of transverse gamma knife beam profiles 

  Bank, Morris I. (American Association of Physicists in Medicine, 2002)

  A microchamber, PTW Pinpoint 31006, was used to measure transverse beam profiles for an Elekta Gamma Knife, Model B, and compared with profiles measured with film dosimetry. The microchamber sensitive volume has a diameter ...
• A semi-empirical model for the therapeutic range shift estimation caused by inhomogeneities in proton beam therapy 

  Moskvin, Vadim; Cheng, Chee-Wai; Fanelli, Leia; Zhao, Li; Das, Indra J. (American Association of Physicists in Medicine, 2012-03-08)

  The purpose of this study was to devise a simple semi-empirical model to estimate the range shift in clinical practices with high-Z inhomogeneity in proton beam. A semi-empirical model utilizing the logarithmic dependence ...
• Congenital ichthyosis patient with squamous cell carcinoma of the skin who received concurrent chemoradiation: A case report 

  Cerra-Franco, Alberto; Grethlein, Sara J.; Bertrand, Todd E.; Wooden, William A.; Saito, Naoyuki G. (Elsevier, 2017-09-05)
• A model combining age, equivalent uniform dose and IL-8 may predict radiation esophagitis in patients with non-small cell lung cancer 

  Wang, Shulian; Campbell, Jeff; Stenmark, Matthew H.; Stanton, Paul; Zhao, Jing; Matuszak, Martha M.; Ten Haken, Randall K.; Kong, Feng-Ming (Elsevier, 2018-03)

  Background and purpose To study whether cytokine markers may improve predictive accuracy of radiation esophagitis (RE) in non-small cell lung cancer (NSCLC) patients. Materials and methods A total of 129 patients with ...
• Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness 

  Zhu, Xingguo; Hu, Tianxiang; Ho, Meng Hsuan; Wang, Yongchao; Yu, Miao; Patel, Niren; Pi, Wenhu; Choi, Jeong-Hyeon; Xu, Hongyan; Ganapathy, Vadivel; Kutlar, Ferdane; Kutlar, Abdullah; Tuan, Dorothy (Ferrata Storti Foundation, 2017-12)

  Hydroxyurea (HU), the first of two drugs approved by the US Food and Drug Administration for treating patients with sickle cell disease (SCD), produces anti-sickling effect by re-activating fetal γ-globin gene to enhance ...
• Ensuring sample quality for blood biomarker studies in clinical trials: a multicenter international study for plasma and serum sample preparation 

  Kong, Feng-Ming (Spring); Zhao, Lujun; Wang, Luhua; Chen, Yuhchyau; Hu, Jie; Fu, Xiaolong; Bai, Chunxue; Wang, Li; Lawrence, Theodore S.; Anscher, Mitchell S.; Dicker, Adam; Okunieff, Paul (2017-12)

  Background Sample quality is critical for biomarker detection in oncology, and platelet degradation and contamination in plasma have a remarkable impact on the ability to accurately quantify many blood-based biomarkers. ...
• Thoracic radiation-induced pleural effusion and risk factors in patients with lung cancer 

  Zhao, Jing; Day, Regina M.; Jin, Jian-Yue; Quint, Leslie; Williams, Hadyn; Ferguson, Catherine; Yan, Li; King, Maurice; Albsheer, Ahmad; Matuszak, Martha; Kong, Feng-Ming (Spring) (Impact Journals, 2017-06-29)

  The risk factors and potential practice implications of radiation-induced pleural effusion (RIPE) are undefined. This study examined lung cancer patients treated with thoracic radiation therapy (TRT) having follow-up ...
• A Multi-Objective Bayesian Networks Approach for Joint Prediction of Tumor Local Control and Radiation Pneumonitis in Non-Small-Cell Lung Cancer (NSCLC) for Response-Adapted Radiotherapy 

  Luo, Yi; McShan, Daniel L.; Matuszak, Martha M.; Ray, Dipankar; Lawrence, Thodore S.; Jolly, Shruti; Kong, Feng-Ming; Ten Haken, Randall K.; El Naqa, Issam (Wiley, 2018)

  Purpose Individualization of therapeutic outcomes in NSCLC radiotherapy is likely to be compromised by the lack of proper balance of biophysical factors affecting both tumor local control (LC) and side effects such as ...
• Challenges of dosimetry of ultra-short pulsed very high energy electron beams 

  Subiel, Anna; Moskvin, Vadim; Welsh, Gregor H.; Cipiccia, Silvia; Reboredo, David; DesRosiers, Colleen; Jaroszynski, Dino A. (Elsevier, 2017-10-01)

  Very high energy electrons (VHEE) in the range from 100 to 250MeV have the potential of becoming an alternative modality in radiotherapy because of their improved dosimetric properties compared with 6–20MV photons generated ...

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