• Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma 

  Schmalbach, Cecelia E.; Bradford, Carol R. (Wiley, 2018-02-05)

  The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic ...
• Hair follicle development in mouse pluripotent stem cell-derived skin organoids 

  Lee, Jiyoon; Boescke, Robert; Tang, Pei-Ciao; Hartman, Byron H.; Heller, Stefan; Koehler, Karl R. (Elsevier, 2018-01-02)

  The mammalian hair follicle arises during embryonic development from coordinated interactions between the epidermis and dermis. It is currently unclear how to recapitulate hair follicle induction in pluripotent stem cell ...
• Survey of endoscopic skull base surgery practice patterns among otolaryngologists 

  Wannemuehler, Todd J.; Rabbani, Cyrus C.; Burgeson, Jack E.; Illing, Elisa A.; Walgama, Evan S.; Wu, Arthur W.; Ting, Jonathan Y. (Wiley, 2018-04-16)

  Background Endoscopic skull base surgery (ESBS) is a rapidly expanding field. Despite divergent reported preferences for reconstructive techniques and perioperative management, limited data exist regarding contemporary ...
• A metabolomic, geographic, and seasonal analysis of the contribution of pollen-derived adenosine to allergic sensitization 

  Mueller, Geoffrey A.; Thompson, Peter M.; DeRose, Eugene F.; O’Connell, Thomas M.; London, Robert E. (Springer Verlag, 2016-12)

  Background Studies on ragweed and birch pollen extracts suggested that the adenosine content is an important factor in allergic sensitization. However, exposure levels from other pollens and considerations of geographic ...
• Factors Affecting Speech Discrimination in Children with Cochlear Implants: Evidence from Early-Implanted Infants 

  Phan, Jennifer; Houston, Derek M.; Ruffin, Chad; Ting, Jonathan; Holt, Rachael Frush (American Academy of Audiology, 2016-06)

  Background To learn words and acquire language, children must be able to discriminate and correctly perceive phonemes. Although there has been much research on the general language outcomes of children with cochlear ...
• Effects of congenital hearing loss and cochlear implantation on audiovisual speech perception in infants and children 

  Bergeson, Tonya R.; Houston, Derek M.; Miyamoto, Richard T. (IOS Press, 2010)

  Purpose Cochlear implantation has recently become available as an intervention strategy for young children with profound hearing impairment. In fact, infants as young as 6 months are now receiving cochlear implants (CIs), ...
• Generation of inner ear organoids with functional hair cells from human pluripotent stem cells 

  Koehler, Karl R.; Nie, Jing; Longworth-Mills, Emma; Liu, Xiao-Ping; Lee, Jiyoon; Holt, Jeffrey R.; Hashino, Eri (Nature Publishing group, 2017-06)

  Human inner ear tissue derived from pluripotent stem cells could provide a powerful platform for drug discovery or a source of sound- or motion-sensing cells for patients with hearing loss or balance dysfunction. Here we ...
• Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells 

  Subramanian, C.; Kovatch, K.J.; Sim, M.W.; Wang, G.; Prince, M.E.; Carey, T.E.; Davis, R.; Blagg, B.S.J.; Cohen, M.S. (Elsevier, 2017-11-06)

  Advanced head and neck squamous cell carcinoma (HNSCC) remains a therapeutic challenge due to the development of therapy resistance. Several studies have implicated the development of cancer stem cells as a possible mechanism ...
• Surgical repair of spontaneous cerebrospinal fluid (CSF) leaks: A systematic review 

  Lobo, Brian C.; Baumanis, Maraya M.; Nelson, Rick F. (Wiley, 2017-04-07)

  Objectives To review the safety and efficacy of surgical management for spontaneous cerebrospinal fluid (CSF) leaks of the anterior and lateral skull base. Data Sources A systematic review of English articles using ...
• An analysis of hearing aid fittings in adults using cochlear implants and contralateral hearing aids 

  Harris, Michael S.; Hay-McCutcheon, Marcia (Wiley, 2010-12)

  OBJECTIVES/HYPOTHESIS: The objective of this study was to assess the appropriateness of hearing aid fittings within a sample of adult cochlear implant recipients who use a hearing aid in the contralateral ear (i.e., bimodal ...
• Improved autologous cortical bone harvest and viability with 2Flute otologic burs 

  Roth, Adam A.; Tang, Pei-Ciao; Ye, Michael J.; Mohammad, Khalid S.; Nelson, Rick F. (Wiley, 2018-01)

  Objectives To determine if 2Flute (Stryker Corporation, Kalamazoo, MI) otologic burs improve the size, cellular content, and bone healing of autologous cortical bone grafts harvested during canal wall reconstruction (CWR) ...
• Three-Dimensional Printing and Its Applications in Otorhinolaryngology–Head and Neck Surgery 

  Crafts, Trevor D.; Ellsperman, Susan E.; Wannemuehler, Todd J.; Bellicchi, Travis D.; Shipchandler, Taha Z.; Mantravadi, Avinash V. (Sage, 2017-06)

  Objective Three-dimensional (3D)-printing technology is being employed in a variety of medical and surgical specialties to improve patient care and advance resident physician training. As the costs of implementing 3D ...
• A clinical pathway for the postoperative management of hypocalcemia after pediatric thyroidectomy reduces blood draws 

  Patel, Neha A.; Bly, Randall A.; Adams, Seth; Carlin, Kristen; Parikh, Sanjay R.; Dahl, John P.; Manning, Scott (Elsevier, 2018-02)

  Objectives Postoperative calcium management is challenging following pediatric thyroidectomy given potential limitations in self-reporting symptoms and compliance with phlebotomy. A protocol was created at our tertiary ...
• The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells 

  Cunningham, Christopher L.; Wu, Zizhen; Jafari, Aria; Zhao, Bo; Schrode, Kat; Harkins-Perry, Sarah; Lauer, Amanda; Müller, Ulrich (eLife Sciences Publications, 2017-05-15)

  Hair cells of the cochlea are mechanosensors for the perception of sound. Mutations in the LRTOMT gene, which encodes a protein with homology to the catecholamine methyltransferase COMT that is linked to schizophrenia, ...
• Outpatient management of cholesteatoma with canal wall reconstruction tympanomastoidectomy 

  Kao, Richard; Wannemuehler, Todd; Yates, Charles W.; Nelson, Rick F. (Wiley, 2017-10-31)

  Objectives The postoperative wound infection rate for canal wall reconstruction (CWR) tympanomastoidectomy with mastoid obliteration in the treatment of chronic otitis media with cholesteatoma has been reported to be ...
• Aspiration of Aluminum Beverage Can Tab: Case Report and Literature Review 

  Elghouche, Alhasan N.; Lobo, Brian C.; Ting, Jonathan Y. (Hindawi, 2017)

  We describe the case of a 16-year-old male who aspirated a beverage can tab resulting in significant functional impairment. Since the introduction of beverage can opening tabs ("pop-tops" or "pull-tabs") nearly 50 years ...
• Reconstruction of midface defect from idiopathic destructive process using Medpor implant 

  Franko, Joel; Harris, Michael S.; Vernon, Dominic; Shipchandler, Taha Z. (Elsevier, 2017-05)

  Importance Reconstruction of the midface remains a challenging task for even the most experienced surgeon, with a host of reconstructive options including free tissue transfer, allografts, or prosthetic implants. Presented ...
• Extra-ocular movement restriction and diplopia following orbital fracture repair 

  Shah, H. A.; Shipchandler, Taha; Vernon, Dominic; Baumanis, Maraya; Chan, David; Nunery, William R.; Lee, Hui Bae Harold (Elsevier, 2017)

  Purpose To report a series of patients with extra-ocular movement restriction and diplopia after orbital fracture repair, and determine the effect of timing of repair and the type of implant used. Methods A chart ...
• Ability of the National Surgical Quality Improvement Program Risk Calculator to Predict Complications Following Total Laryngectomy 

  Schneider, Alexander L.; Deig, Christopher R.; Prasad, Kumar G.; Nelson, Benton G.; Mantravadi, Avinash V.; Brigance, Joseph S.; Langer, Mark P.; McDonald, Mark W.; Johnstone, Peter A.; Moore, Michael G. (JAMA, 2016-10)

  Importance The accuracy of the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) risk calculator has been assessed in multiple surgical subspecialties; however, there have been no publications ...
• A Systematic Review Including an Additional Pediatric Case Report: Pediatric Cases of Mammary Analogue Secretory Carcinoma 

  Ngouajio, Amanda L.; Drejet, Sarah M.; Phillips, Ryan; Summerlin, Don-John; Dahl, John P. (Elsevier, 2017-09)

  Importance Mammary Analogue Secretory Carcinoma (MASC) is a newly characterized salivary gland carcinoma resembling secretory carcinoma of the breast. Prior to being described, MASC was most commonly misdiagnosed as ...

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