• Sperm function, protein phosphorylation, and metabolism differ in mice lacking successive sperm-specific glycolytic enzymes† 

  Huang, Zaohua; Danshina, Polina V.; Mohr, Kathleen; Qu, Weidong; Goodson, Summer G.; O'Connell, Thomas M.; O'Brien, Deborah A. (Oxford, 2017-10)

  Glyceraldehyde 3-phosphate dehydrogenase-S (GAPDHS) and phosphoglycerate kinase 2 (PGK2), two isozymes restricted to the male germline, catalyze successive steps in the glycolytic pathway in mammalian sperm. Although gene ...
• Three challenges for future research on cochlear implants 

  Pisoni, David B.; Kronenberger, William G.; Harris, Michael S.; Moberly, Aaron C. (Elsevier, 2018-01-02)

  Cochlear implants (CIs) often work very well for many children and adults with profound sensorineural (SNHL) hearing loss. Unfortunately, while many CI patients display substantial benefits in recognizing speech and ...
• 12 guiding premises of pediatric cochlear implant habilitation 

  Robbins, Amy McConkey (ScienceDirect, 2018-02-28)
• Introduction 

  Miyamoto, Richard T. (ScienceDirect, 2017-12)
• Cochlear implantation in infants below 12 months of age 

  Miyamoto, Richard T.; Colson, Bethany; Henning, Shirley; Pisoni, David (Elsevier, 2018-02-03)

  To provide safety and efficacy data on infants implanted below 12 months of age. Methods: With the wide application of newborn hearing screening programs, infants with deafness are being identified at birth. When a ...
• Scar Revision: Surgical and Nonsurgical Options 

  Kadakia, Sameep; Ducic, Yadranko; Jategaonkar, Ameya; Chan, David (Thieme, 2017)

  Facial scarring represents a challenging issue for the facial plastic surgeon owing to the unpredictable and variable nature of scar formation. The psychologic, cosmetic, and functional implications of facial scars oftentimes ...
• Repair of the Malpositioned Lower Lid 

  Chan, David; Sokoya, Mofiyinfolu; Ducic, Yadranko (Thieme, 2017)

  Complications from surgical approaches to the orbit can be associated with debilitating morbidity and negative surgical outcomes. The surgeon must be familiar with the different factors that predispose a patient to these ...
• Clinically small tonsils are typically not obstructive in children during drug-induced sleep endoscopy 

  Miller, Craig; Purcell, Patricia L.; Dahl, John P.; Johnson, Kaalan; Horn, David L.; Chen, Maida L.; Chan, Dylan K.; Parikh, Sanjay R. (Wiley, 2017-08)

  OBJECTIVE: To determine whether the degree of lateral pharyngeal wall (LPW) obstruction on pediatric drug-induced sleep endoscopy (DISE) correlates with preprocedure tonsillar hypertrophy score on physical examination, ...
• Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2 

  Wahle, Benjamin M.; Hawley, Eric T.; He, Yongzheng; Smith, Abbi E.; Yuan, Jin; Masters, Andi R.; Jones, David R.; Gehlhausen, Jeffrey R.; Park, Su-Jung; Conway, Simon J.; Clapp, D. Wade; Yates, Charles W. (Impact Journals, 2017-10-24)

  Mutations in the tumor suppressor gene NF2 lead to Neurofibromatosis type 2 (NF2), a tumor predisposition syndrome characterized by the development of schwannomas, including bilateral vestibular schwannomas with complete ...
• The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex 

  Patel, Dharmeshkumar; Shimomura, Atsushi; Majumdar, Sreeparna; Holley, Matthew C.; Hashino, Eri (Public Library of Science, 2018-01-25)

  The histone demethylase LSD1 plays a pivotal role in cellular differentiation, particularly in silencing lineage-specific genes. However, little is known about how LSD1 regulates neurosensory differentiation in the inner ...
• Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma 

  Schmalbach, Cecelia E.; Bradford, Carol R. (Wiley, 2018-02-05)

  The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic ...
• Hair follicle development in mouse pluripotent stem cell-derived skin organoids 

  Lee, Jiyoon; Boescke, Robert; Tang, Pei-Ciao; Hartman, Byron H.; Heller, Stefan; Koehler, Karl R. (Elsevier, 2018-01-02)

  The mammalian hair follicle arises during embryonic development from coordinated interactions between the epidermis and dermis. It is currently unclear how to recapitulate hair follicle induction in pluripotent stem cell ...
• Survey of endoscopic skull base surgery practice patterns among otolaryngologists 

  Wannemuehler, Todd J.; Rabbani, Cyrus C.; Burgeson, Jack E.; Illing, Elisa A.; Walgama, Evan S.; Wu, Arthur W.; Ting, Jonathan Y. (Wiley, 2018-04-16)

  Background Endoscopic skull base surgery (ESBS) is a rapidly expanding field. Despite divergent reported preferences for reconstructive techniques and perioperative management, limited data exist regarding contemporary ...
• A metabolomic, geographic, and seasonal analysis of the contribution of pollen-derived adenosine to allergic sensitization 

  Mueller, Geoffrey A.; Thompson, Peter M.; DeRose, Eugene F.; O’Connell, Thomas M.; London, Robert E. (Springer Verlag, 2016-12)

  Background Studies on ragweed and birch pollen extracts suggested that the adenosine content is an important factor in allergic sensitization. However, exposure levels from other pollens and considerations of geographic ...
• Factors Affecting Speech Discrimination in Children with Cochlear Implants: Evidence from Early-Implanted Infants 

  Phan, Jennifer; Houston, Derek M.; Ruffin, Chad; Ting, Jonathan; Holt, Rachael Frush (American Academy of Audiology, 2016-06)

  Background To learn words and acquire language, children must be able to discriminate and correctly perceive phonemes. Although there has been much research on the general language outcomes of children with cochlear ...
• Effects of congenital hearing loss and cochlear implantation on audiovisual speech perception in infants and children 

  Bergeson, Tonya R.; Houston, Derek M.; Miyamoto, Richard T. (IOS Press, 2010)

  Purpose Cochlear implantation has recently become available as an intervention strategy for young children with profound hearing impairment. In fact, infants as young as 6 months are now receiving cochlear implants (CIs), ...
• Generation of inner ear organoids with functional hair cells from human pluripotent stem cells 

  Koehler, Karl R.; Nie, Jing; Longworth-Mills, Emma; Liu, Xiao-Ping; Lee, Jiyoon; Holt, Jeffrey R.; Hashino, Eri (Nature Publishing group, 2017-06)

  Human inner ear tissue derived from pluripotent stem cells could provide a powerful platform for drug discovery or a source of sound- or motion-sensing cells for patients with hearing loss or balance dysfunction. Here we ...
• Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells 

  Subramanian, C.; Kovatch, K.J.; Sim, M.W.; Wang, G.; Prince, M.E.; Carey, T.E.; Davis, R.; Blagg, B.S.J.; Cohen, M.S. (Elsevier, 2017-11-06)

  Advanced head and neck squamous cell carcinoma (HNSCC) remains a therapeutic challenge due to the development of therapy resistance. Several studies have implicated the development of cancer stem cells as a possible mechanism ...
• Surgical repair of spontaneous cerebrospinal fluid (CSF) leaks: A systematic review 

  Lobo, Brian C.; Baumanis, Maraya M.; Nelson, Rick F. (Wiley, 2017-04-07)

  Objectives To review the safety and efficacy of surgical management for spontaneous cerebrospinal fluid (CSF) leaks of the anterior and lateral skull base. Data Sources A systematic review of English articles using ...
• An analysis of hearing aid fittings in adults using cochlear implants and contralateral hearing aids 

  Harris, Michael S.; Hay-McCutcheon, Marcia (Wiley, 2010-12)

  OBJECTIVES/HYPOTHESIS: The objective of this study was to assess the appropriateness of hearing aid fittings within a sample of adult cochlear implant recipients who use a hearing aid in the contralateral ear (i.e., bimodal ...

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