• Findings From a Scoping Review: Presumptive Treatment for Chlamydia trachomatis and Neisseria gonorrhoeae in the United States, 2006–2021 

  Allen, Katie S.; Hinrichs, Rachel J.; Heumann, Christine L.; Titus, Melissa K.; Duszynski, Thomas J.; Valvi, Nimish R.; Wiensch, Ashley; Tao, Guoyu; Dixon, Brian E. (American Sexually Transmitted Diseases Association, 2023-04)

  Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) are the 2 most common reported sexually transmitted infections in the United States. Current recommendations are to presumptively treat CT and/or GC in persons with ...
• Longitudinal Plasma Metabolomics Profile in Pregnancy—A Study in an Ethnically Diverse U.S. Pregnancy Cohort 

  Mitro, Susanna D.; Wu, Jing; Rahman, Mohammad L.; Cao, Yaqi; Zhu, Yeyi; Chen, Zhen; Chen, Liwei; Li, Mengying; Hinkle, Stefanie N.; Bremer, Andrew A.; Weir, Natalie L.; Tsai, Michael Y.; Song, Yiqing; Grantz, Katherine L.; Gelaye, Bizu; Zhang, Cuilin (MDPI, 2021-09-01)

  Amino acids, fatty acids, and acylcarnitine metabolites play a pivotal role in maternal and fetal health, but profiles of these metabolites over pregnancy are not completely established. We described longitudinal trajectories ...
• Genetic variants in TKT and DERA in the NADPH pathway predict melanoma survival 

  Gu, Ning; Dai, Wei; Liu, Hongliang; Ge, Jie; Luo, Sheng; Cho, Eunyoung; Amos, Christopher I.; Lee, Jeffrey E.; Li, Xin; Nan, Hongmei; Yuan, Hua; Wei, Qingyi (Elsevier, 2020-09)

  Background: Cutaneous melanoma (CM) is the most lethal type of skin cancers. Nicotinamide adenine dinucleotide phosphate (NADPH) plays an important role in anabolic reactions and tumorigenesis, but many genes are involved ...
• Genetic risk for primordial prevention of cardiometabolic disease 

  Wessel, Jennifer; Smith, Mitchell (2019-06)

  The prevalence of obesity and type 2 diabetes (T2D) in children has risen dramatically. We hypothesized that providing child’s genetic risk information, to families at high T2D risk, would serve as a motivator to improve ...
• Race-specific associations of 25-hydroxyvitamin D and parathyroid hormone with cardiometabolic biomarkers among US white and black postmenopausal women 

  Xia, Jin; Tu, Wanzhu; Manson, JoAnn E.; Nan, Hongmei; Shadyab, Aladdin H.; Bea, Jennifer W.; Cheng, Ting-Yuan D.; Hou, Lifang; Song, Yiqing (Elsevier, 2020-08-01)

  Background: Concentrations of 25-hydroxyvitamin D [25(OH)D] tend to be lower in African Americans than in non-Hispanic whites, but whether adding information on parathyroid hormone (PTH) can help explain the higher ...
• Insulinemic Potential of Lifestyle Is Inversely Associated with Leukocyte Mitochondrial DNA Copy Number in US White Adults 

  Yang, Keming; Forman, Michele R.; Monahan, Patrick O.; Graham, Brett H.; Chan, Andrew T.; Zhang, Xuehong; De Vivo, Immaculata; Giovannucci, Edward L.; Tabung, Fred K.; Nan, Hongmei (Elsevier, 2020-08-01)

  Background: Poor lifestyles have been linked to insulin insensitivity/hyperinsulinemia, which may contribute to downstream changes such as inflammation and oxidative damage and the development of chronic diseases. As a ...
• Plans in Perspective: a Pilot Study of Medical Student Study Strategies in Physiology 

  Husmann, Polly R.; Chong, Alexander J. (Springer, 2019-07-15)

  Students learn a great deal when they study course material outside of our classrooms, but we have little hard evidence of what they are actually doing during that time and how it varies over the course of the semester. ...
• Genetic variants of EML1 and HIST1H4E in myeloid cell-related pathway genes independently predict cutaneous melanoma-specific survival 

  He, Yuanmin; Liu, Hongliang; Luo, Sheng; Amos, Christopher I.; Lee, Jeffrey E.; Yang, Keming; Qureshi, Abrar A.; Han, Jiali; Wei, Qingyi (e-Century Publishing, 2021-06-15)

  Both in vivo and in vitro evidence has supported a key role of myeloid cells in immune suppression in melanoma and in promoting melanocytic metastases. Some single-nucleotide polymorphisms (SNPs) have been shown to predict ...
• How Many SARS-CoV-2–Infected People Require Hospitalization? Using Random Sample Testing to Better Inform Preparedness Efforts 

  Menachemi, Nir; Dixon, Brian E.; Wools-Kaloustian, Kara K.; Yiannoutsos, Constantin T.; Halverson, Paul K. (Wolters Kluwer, 2021)

  Context: Existing hospitalization ratios for COVID-19 typically use case counts in the denominator, which problematically underestimates total infections because asymptomatic and mildly infected persons rarely get tested. ...
• Intake of Calcium, Magnesium, and Phosphorus and Risk of Pancreatic Cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial 

  Hoyt, Margaret; Song, Yiqing; Gao, Sujuan; O'Palka, Jacquelynn; Zhang, Jianjun (Taylor & Francis, 2021)

  ObjectiveFew epidemiological studies have investigated the associations between calcium, magnesium, and phosphorus intake and pancreatic cancer. We examined these associations in the Prostate, Lung, Colorectal and Ovarian ...
• Probiotic and Oxytocin Combination Therapy in Patients with Autism Spectrum Disorder: A Randomized, Double-Blinded, Placebo-Controlled Pilot Trial 

  Kong, Xue-Jun; Liu, Jun; Liu, Kevin; Koh, Madelyn; Sherman, Hannah; Liu, Siyu; Tian, Ruiyi; Sukijthamapan, Piyawat; Wang, Jiuju; Fong, Michelle; Xu, Lei; Clairmont, Cullen; Jeong, Min-Seo; Li, Alice; Lopes, Maria; Hagan, Veronica; Dutton, Tess; Chan, Suk-Tak (Phoebe); Lee, Hang; Kendall, Amy; Kwong, Kenneth; Song, Yiqing (MDPI, 2021-05-05)

  Autism spectrum disorder (ASD) is a rapidly growing neurodevelopmental disorder. Both probiotics and oxytocin were reported to have therapeutic potential; however, the combination therapy has not yet been studied. We ...
• Improving Notifiable Disease Case Reporting Through Electronic Information Exchange–Facilitated Decision Support: A Controlled Before-and-After Trial 

  Dixon, Brian E.; Zhang, Zuoyi; Arno, Janet N.; Revere, Debra; Gibson, P. Joseph; Grannis, Shaun J. (Sage, 2020)

  Objective: Outbreak detection and disease control may be improved by simplified, semi-automated reporting of notifiable diseases to public health authorities. The objective of this study was to determine the effect of an ...
• Association of genetic variants of TMEM135 and PEX5 in the peroxisome pathway with cutaneous melanoma-specific survival 

  Wang, Haijiao; Liu, Hongliang; Dai, Wei; Luo, Sheng; Amos, Christopher I.; Lee, Jeffrey E.; Li, Xin; Yue, Ying; Nan, Hongmei; Wei, Qingyi (AME Publishing, 2021-03)

  Background: Peroxisomes are ubiquitous and dynamic organelles that are involved in the metabolism of reactive oxygen species (ROS) and lipids. However, whether genetic variants in the peroxisome pathway genes are associated ...
• Viime: Visualization and Integration of Metabolomics Experiments 

  Choudhury, Roni; Beezley, Jon; Davis, Brandon; Tomeck, Jared; Gratzl, Samuel; Golzarri-Arroyo, Lilian; Wan, Jun; Raftery, Daniel; Baumes, Jeff; O’Connell, Thomas M. (Open Journals, 2020)

  Metabolomics involves the comprehensive measurement of metabolites from a biological system. The resulting metabolite profiles are influenced by genetics, lifestyle, biological stresses, disease, diet and the environment ...
• Long-term effects of a toddler-focused caries prevention programme among Northwestern US tribal children: The TOTS-to-Tweens study 

  Smith, Nicole Holdaway; Lutz, Tam; Maupomé, Gerardo; Lapidus, Jodi; Jimenez, Candice; Janis, Maxine; Schwarz, Eli; Becker, Thomas (Wiley, 2021-06)

  OBJECTIVES: We sought to determine whether American Indian tribe-based interventions that successfully prevented toddler dental caries in a 2005 cohort study (the Toddler Overweight and Tooth Decay Prevention Study, or ...
• Neurodegenerative Patterns of Cognitive Clusters of Early-Onset Alzheimer's Disease Subjects: Evidence for Disease Heterogeneity 

  Phillips, Meredith L.; Stage, Eddie C., Jr.; Lane, Kathleen A.; Gao, Sujuan; Risacher, Shannon L.; Goukasian, Naira; Saykin, Andrew J.; Carrillo, Maria C.; Dickerson, Bradford C.; Rabinovici, Gil D.; Apostolova, Liana G. (Karger, 2019)

  Background/aims: Alzheimer's disease (AD) with onset before 65 (early-onset AD [EOAD]) occurs in approximately 6% of cases and can affect nonmemory domains. Here, we analyze patterns of impairment in amnestic EOAD individuals ...
• Citrus Consumption and Risk of Cutaneous Malignant Melanoma in the Women’s Health Initiative 

  Melough, Melissa M.; Wu, Shaowei; Li, Wen-Qing; Eaton, Charles; Nan, Hongmei; Snetselaar, Linda; Wallace, Robert; Qureshi, Abrar A.; Chun, Ock K.; Cho, Eunyoung (Routledge, 2020)

  Citrus products are rich sources of furocoumarins, a class of photoactive compounds. Certain furocoumarins combined with ultraviolet radiation can induce skin cancer. We examined the relationship between citrus consumption ...
• The Effects of a Mediterranean Diet Intervention on Targeted Plasma Metabolic Biomarkers among US Firefighters: A Pilot Cluster-Randomized Trial 

  Sotos-Prieto, Mercedes; Ruiz-Canela, Miguel; Song, Yiqing; Christophi, Costas; Mofatt, Steven; Rodriguez-Artalejo, Fernando; Kales, Stefanos N. (MDPI, 2020-11-24)

  Metabolomics is improving the understanding of the mechanisms of the health effects of diet. Previous research has identified several metabolites associated with the Mediterranean Diet (MedDiet), but knowledge about ...
• Novel Genetic Variants of ALG6 and GALNTL4 of the Glycosylation Pathway Predict Cutaneous Melanoma-Specific Survival 

  Zhou, Bingrong; Zhao, Yu Chen; Liu, Hongliang; Luo, Sheng; Amos, Christopher I.; Lee, Jeffrey E.; Li, Xin; Nan, Hongmei; Wei, Qingyi (MDPI, 2020-01-24)

  Because aberrant glycosylation is known to play a role in the progression of melanoma, we hypothesize that genetic variants of glycosylation pathway genes are associated with the survival of cutaneous melanoma (CM) patients. ...
• The synchronicity of COVID-19 disparities: Statewide epidemiologic trends in SARS-CoV-2 morbidity, hospitalization, and mortality among racial minorities and in rural America 

  Dixon, Brian E.; Grannis, Shaun J.; Lembcke, Lauren R.; Valvi, Nimish; Roberts, Anna R.; Embi, Peter J. (PLOS One, 2021-07-20)

  Background Early studies on COVID-19 identified unequal patterns in hospitalization and mortality in urban environments for racial and ethnic minorities. These studies were primarily single center observational studies ...

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