Department of Biostatistics

Department of Biostatistics

 

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Recent Submissions

  • Abraham, Allistair A.; John, Tami D.; Keller, Michael D.; Cruz, C. Russell N.; Salem, Baheyeldin; Roesch, Lauren; Liu, Hao; Hoq, Fahmida; Grilley, Bambi J.; Gee, Adrian P.; Dave, Hema; Jacobsohn, David A.; Krance, Robert A.; Shpall, Elizabeth. J.; Martinez, Caridad A.; Hanley, Patrick J.; Bollard, Catherine M. (American Society of Hematology, 2019-07-23)
    Adoptive transfer of virus-specific T cells (VSTs) has been shown to be safe and effective in stem cell transplant recipients. However, the lack of virus-experienced T cells in donor cord blood (CB) has prevented the ...
  • Lu, Xin; Pan, Xiaolu; Wu, Chang-Jiun; Zhao, Di; Feng, Shan; Zang, Yong; Lee, Rumi; Khadka, Sunada; Amin, Samirkumar B.; Jin, Eun-Jung; Shang, Xiaoying; Deng, Pingna; Luo, Yanting; Morgenlander, William R.; Weinrich, Jacqueline; Lu, Xuemin; Jiang, Shan; Chang, Qing; Navone, Nora M.; Troncoso, Patricia; DePinho, Ronald A.; Wang, Y. Alan (American Association for Cancer Research, 2018-07-15)
    Advanced prostate cancer displays conspicuous chromosomal instability and rampant copy number aberrations, yet the identity of functional drivers resident in many amplicons remain elusive. Here, we implemented a functional ...
  • Pisoni, David B.; Broadstock, Arthur; Wucinich, Taylor; Safdar, Natalie; Miller, Kelly; Hernandez, Luis R.; Vasil, Kara; Boyce, Lauren; Davies, Alexandra; Harris, Michael S.; Castellanos, Irina; Xu, Huiping; Kronenberger, William G.; Moberly, Aaron C. (Wolters Kluwer, 2018)
    OBJECTIVES: Despite the importance of verbal learning and memory in speech and language processing, this domain of cognitive functioning has been virtually ignored in clinical studies of hearing loss and cochlear implants ...
  • Zhou, Wenjun; He, Yanlin; Rehman, Atteeq U.; Kong, Yan; Hong, Sungguan; Ding, Guolian; Yalamanchili, Hari Krishna; Wan, Ying-Wooi; Paul, Basil; Wang, Chuhan; Gong, Yingyun; Zhou, Wenxian; Liu, Hao; Dean, John; Scalais, Emmanuel; O’Driscoll, Mary; Morton, Jenny E.V.; Hou, Xinguo; Wu, Qi; Tong, Qingchun; Liu, Zhandong; Liu, Pengfei; Xu, Yong; Sun, Zheng (Springer Nature, 2019-02)
    Nuclear receptor corepressor 1 (NCOR1) and NCOR2 (also known as SMRT) regulate gene expression by activating histone deacetylase 3 through their deacetylase activation domain (DAD). We show that mice with DAD knock-in ...
  • Tymejczyk, Olga; Brazier, Ellen; Yiannoutsos, Constantin T.; Vinikoor, Michael; van Lettow, Monique; Nalugoda, Fred; Urassa, Mark; Sinayobye, Jean d’Amour; Rebeiro, Peter F.; Wools-Kaloustian, Kara; Davies, Mary-Ann; Zaniewski, Elizabeth; Anderegg, Nanina; Liu, Grace; Ford, Nathan; Nash, Denis (PLOS, 2019-06-10)
    BACKGROUND: Most countries have formally adopted the World Health Organization's 2015 recommendation of universal HIV treatment ("treat all"). However, there are few rigorous assessments of the real-world impact of treat ...
  • Khan, Babar A.; Perkins, Anthony J.; Campbell, Noll L.; Gao, Sujuan; Farber, Mark O.; Wang, Sophia; Khan, Sikandar H.; Zarzaur, Ben L.; Boustani, Malaz A. (Wiley, 2019-05)
    BACKGROUND/OBJECTIVE: Delirium in the intensive care units (ICUs) is prevalent, with both delirium duration and delirium severity associated with adverse outcomes. We designed a pragmatic trial to test the efficacy of ...
  • Kerns, Sarah L.; Fung, Chunkit; Monahan, Patrick O.; Ardeshir-Rouhani-Fard, Shirin; Abu Zaid, Mohammad I.; Williams, AnnaLynn M.; Stump, Timothy E.; Sesso, Howard D.; Feldman, Darren R.; Hamilton, Robert J.; Vaughn, David J.; Beard, Clair; Huddart, Robert A.; Kim, Jeri; Kollmannsberger, Christian; Sahasrabudhe, Deepak M.; Cook, Ryan; Fossa, Sophie D.; Einhorn, Lawrence H.; Travis, Lois B. (American Society of Clinical Oncology, 2018-05-20)
    Purpose In this multicenter study, we evaluated the cumulative burden of morbidity (CBM) among > 1,200 testicular cancer survivors and applied factor analysis to determine the co-occurrence of adverse health outcomes (AHOs). ...
  • Ahmed, Sheikh Sohail; Nitu, Mara; Hicks, Shawn; Hedlund, Lauren; Slaven, James E.; Rigby, Mark R. (Thieme, 2016-03)
    Objective Examine comparative dosing, efficacy, and safety of propofol alone or with an initial, subdissociative dose of ketamine approach for deep sedation. Background Propofol is a sedative-hypnotic agent used increasingly ...
  • Ahmed, Sheikh Sohail; Hicks, Shawn; Slaven, James E.; Nitu, Mara (Thieme, 2017-09)
    Objective  A comparison of intermittent bolus (IB) versus continuous infusion of propofol for deep sedation. Material and Methods  A retrospective review of patients sedated for Auditory Brainstem Response (ABR)/nuclear ...
  • Shu, Yin; Feng, Qianmei; Liu, Hao (Elsevier, 2019-11)
    Degradation-with-jump measures are time series data sets containing the information of both continuous and randomly jumping degradation evolution of a system. Traditional maximum likelihood estimation and Bayesian estimation ...
  • Sun, Huiyan; Chen, Liang; Cao, Sha; Liang, Yanchun; Xu, Ying (Elsevier, 2019)
    It has been observed that both cancer tissue cells and normal proliferating cells (NPCs) have the Warburg effect. Our goal here is to demonstrate that they do this for different reasons. To accomplish this, we have analyzed ...
  • McHenry, Megan S.; McAteer, Carole I.; Oyungu, Eren; McDonald, Brenna C.; Bosma, Chris B.; Mpofu, Philani B.; Deathe, Andrew R.; Vreeman, Rachel C. (American Academy of Pediatrics, 2018-02)
    CONTEXT: HIV-infected (HIV+) children have worse neurodevelopmental outcomes compared with HIV-uninfected children. However, little is known regarding the differences in neurodevelopment between young HIV+ children, ...
  • Hurtz, Sona; Chow, Nicole; Watson, Amity E.; Somme, Johanne H.; Goukasian, Naira; Hwang, Kristy S.; Morra, John; Elashoff, David; Gao, Sujuan; Petersen, Ronald C.; Aisen, Paul S.; Thompson, Paul M.; Apostolova, Liana G. (Elsevier, 2019)
    BACKGROUND: Imaging techniques used to measure hippocampal atrophy are key to understanding the clinical progression of Alzheimer's disease (AD). Various semi-automated hippocampal segmentation techniques are available ...
  • Urbanek, Jacek K.; Zipunnikov, Vadim; Harris, Tamara; Fadel, William; Glynn, Nancy; Koster, Annemarie; Caserotti, Paolo; Crainiceanu, Ciprian; Harezlak, Jaroslaw (IOP Publishing, 2018-02-28)
    OBJECTIVE: Using raw, sub-second-level accelerometry data, we propose and validate a method for identifying and characterizing walking in the free-living environment. We focus on sustained harmonic walking (SHW), which ...
  • Slaven, James E.; Haas, David W.; Liu, Ziyue; Stein, James H.; Brown, Todd T.; Gupta, Samir K. (Wolters Kluwer, 2019-05)
    Heightened systemic inflammation contributes to cardiovascular (CVD) events in people living with HIV (PLWH), though not all PLWH develop CVD, thus suggesting a genetic modifying role. We examined GCH1 polymorphisms, which ...
  • Downing, Nancy R.; Lourens, Spencer; De Soriano, Isabella; Long, Jeffrey D.; Paulsen, Jane S.; PREDICT-HD Investigators and Coordinators of the Huntington Study Group (IOS Press, 2016-12-15)
    BACKGROUND: Huntington disease (HD) is a neurodegenerative disease caused by a CAG repeat expansion on chromosome 4. Pathology is associated with CAG repeat length. Prior studies examining people in the intermediate ...
  • Zang, Yong; Fung, Wing Kam; Cao, Sha; Ng, Hon Keung Tony; Zhang, Chi (Elsevier, 2019-01)
    The case-control and case-only designs are commonly used to detect the gene–environment (G–E) interaction. In principle, the tests based on these two designs require a pre-specified genetic model to achieve an expected ...
  • Devnani, Rohit; Slaven, James E., Jr.; Bosslet, Gabriel T.; Montz, Kianna; Inger, Lev; Burke, Emily S.; Torke, Alexia M. (Springer Nature, 2017-12)
    BACKGROUND: Many hospitalized adults do not have the capacity to make their own health care decisions and thus require a surrogate decision-maker. While the ethical standard suggests that decisions should focus on a ...
  • Kagaris, Dimitri; Khamesipour, Alireza; Yiannoutsos, Constantin T. (BMC, 2018-06-26)
    The Top Scoring Pair (TSP) classifier, based on the concept of relative ranking reversals in the expressions of pairs of genes, has been proposed as a simple, accurate, and easily interpretable decision rule for classification ...
  • Bakoyannis, Giorgos; Yu, Menggang; Yiannoutsos, Constantin T. (Wiley, 2017-10-15)
    Many biomedical and clinical studies with time-to-event outcomes involve competing risks data. These data are frequently subject to interval censoring. This means that the failure time is not precisely observed but is only ...

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