Browsing Department of Surgery by Author "Wan, Jun"

Browsing Department of Surgery by Author "Wan, Jun"

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  • Padua, Maria B.; Bhat-Nakshatri, Poornima; Anjanappa, Manjushree; Prasad, Mayuri S.; Hao, Yangyang; Rao, Xi; Liu, Sheng; Wan, Jun; Liu, Yunlong; McElyea, Kyle; Jacobsen, Max; Sandusky, George; Althouse, Sandra; Perkins, Susan; Nakshatri, Harikrishna (BMC, 2018-05-02)
    BACKGROUND: The majority of estrogen receptor-positive (ERα+) breast cancers respond to endocrine therapies. However, resistance to endocrine therapies is common in 30% of cases, which may be due to altered ERα signaling ...
  • Liu, Yunhua; Xu, Hanchen; Van der Jeught, Kevin; Li, Yujing; Liu, Sheng; Zhang, Lu; Fang, Yuanzhang; Zhang, Xinna; Radovich, Milan; Schneider, Bryan P.; He, Xiaoming; Huang, Cheng; Zhang, Chi; Wan, Jun; Ji, Guang; Lu, Xiongbin (American Society for Clinical Investigation, 2018-07-02)
    A synthetic lethality-based strategy has been developed to identify therapeutic targets in cancer harboring tumor-suppressor gene mutations, as exemplified by the effectiveness of poly ADP-ribose polymerase (PARP) inhibitors ...

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