Sunil Badve

 

Recent Submissions

  • Nakshatri, H.; Appaiah, H. N.; Anjanappa, M.; Gilley, D.; Tanaka, H.; Badve, Sunil; Crooks, P. A.; Mathews, W.; Sweeney, C.; Bhat-Nakshatri, P. (Nature Publishing Group, 2015-01-22)
    The transcription factor nuclear factor-kappaB (NF-κB) is constitutively active in several cancers and is a target of therapeutic development. We recently developed dimethylaminoparthenolide (DMAPT), a clinical grade ...
  • Burnett, Riesa M.; Craven, Kelly E.; Krishnamurthy, Purna; Goswami, Chirayu P.; Badve, Sunil; Crooks, Peter; Mathews, William P.; Bhat-Nakshatri, Poornima; Nakshatri, Harikrishna (Impact Journals, LLC, 2015-05-20)
    Breast cancer metastasizes to bone, visceral organs, and/or brain depending on the subtype, which may involve activation of a host organ-specific signaling network in metastatic cells. To test this possibility, we determined ...
  • Provenzano, Elena; Bossuyt, Veerle; Viale, Giuseppe; Cameron, David; Badve, Sunil; Denkert, Carsten; MacGrogan, Gaëtan; Penault-Llorca, Frédérique; Boughey, Judy; Curigliano, Giuseppe; Dixon, J. Michael; Esserman, Laura; Fastner, Gerd; Kuehn, Thorsten; Peintinger, Florentia; von Minckwitz, Gunter; White, Julia; Yang, Wei; Symmans, W. Fraser (Nature, 2015-07)
    Neoadjuvant systemic therapy is being used increasingly in the treatment of early-stage breast cancer. Response, in the form of pathological complete response, is a validated and evaluable surrogate end point of survival ...
  • Woditschka, Stephan; Evans, Lynda; Duchnowska, Renata; Reed, L. Tiffany; Palmieri, Diane; Qian, Yongzhen; Badve, Sunil; Sledge, George; Gril, Brunilde; Aladjem, Mirit I.; Fu, Haiqing; Flores, Natasha M.; Gökmen-Polar, Yesim; Biernat, Wojciech; Szutowicz-Zielińska, Ewa; Mandat, Tomasz; Trojanowski, Tomasz; Och, Waldemar; Czartoryska-Arlukowicz, Bogumiła; Jassem, Jacek; Mitchell, James B.; Steeg, Patricia S. (Oxford University Press, )
    Background Breast cancer frequently metastasizes to the brain, colonizing a neuro-inflammatory microenvironment. The molecular pathways facilitating this colonization remain poorly understood. Methods Expression ...
  • Duchnowska, Renata; Jassem, Jacek; Goswami, Chirayu Pankaj; Dundar, Murat; Gökmen-Polar, Yesim; Li, Lang; Woditschka, Stephan; Biernat, Wojciech; Sosińska-Mielcarek, Katarzyna; Czartoryska-Arłukowicz, Bogumiła; Radecka, Barbara; Tomasevic, Zorica; Stępniak, Piotr; Wojdan, Konrad; Sledge, George W. Jr.; Steeg, Patricia S.; Badve, Sunil (Springer US, 2015-03)
    The overexpression or amplification of the human epidermal growth factor receptor 2 gene (HER2/neu) is associated with high risk of brain metastasis (BM). The identification of patients at highest immediate risk of BM could ...
  • Gokmen-Polar, Yesim; Vladislav, I. Tudor; Neelamraju, Yaseswini; Janga, Sarath C.; Badve, Sunil (Nature Publishing Group, 2015-03-05)
    Expression of HOX transcript antisense intergenic RNA (HOTAIR), a large intergenic noncoding RNA (lincRNA), has been described as a metastases-associated lincRNA in various cancers including breast, liver and colon cancer ...
  • Radovich, Milan; Clare, Susan E.; Atale, Rutuja; Pardo, Ivanesa; Hancock, Bradley A.; Solzak, Jeffrey P.; Kassem, Nawal; Mathieson, Theresa; V. Storniolo, Anna Maria; Rufenbarger, Connie; Lillemoe, Heather A.; Blosser, Rachel J.; Choi, Mi Ran; Sauder, Candice A.; Doxey, Diane; Henry, Jill E.; Hilligoss, Eric E.; Sakarya, Onur; Hyland, Fiona C.; Hickenbotham, Matthew; Zhu, Jin; Glasscock, Jarret; Badve, Sunil; Ivan, Mircea; Liu, Yunlong; Sledge, George W.; Schneider, Bryan P. (Springer, 2014-01)
    Triple-negative breast cancers (TNBCs) are a heterogeneous set of tumors defined by an absence of actionable therapeutic targets (ER, PR, and HER-2). Microdissected normal ductal epithelium from healthy volunteers represents ...
  • Sledge Jr., George W.; Badve, Sunil; Bales, Casey; Gill, Erin M.; Gilley, David P.; Goswami, Chirayu; Wells, Clark D.; Ziner, Kim W.; Nakshatri, Harikrishna (Office of the Vice Chancellor for Research, 2012-04-13)
    Abstract The Indiana Center for Breast Cancer Research (ICBCR) was funded under the IUPUI Signature Center Initiative in 2010. Its mission is to address the full range of prevention, early detection, and treatment of ...
  • Perkins, Susan M.; Bales, Casey; Vladislav, Tudor; Althouse, Sandra; Miller, Kathy D.; Sandusky, George; Badve, Sunil; Nakshatri, Harikrishna (Springer, 2015-08)
    Recurrence and death in a significant number of patients with ERα-positive breast cancer occurs 10–20 years after diagnosis. Prognostic markers for late events have been more elusive. TFAP2C (AP2γ) regulates the expression ...
  • Gökmen-Polar, Yesim; Neelamraju, Yaseswini; Goswami, Chirayu P.; Gu, Xiaoping; Nallamothu, Gouthami; Janga, Sarath Chandra; Badve, Sunil (Nature Publishing Group, 2015-05)
    De novo or acquired resistance to endocrine therapy limits its utility in a significant number of estrogen receptor-positive (ER-positive) breast cancers. It is crucial to identify novel targets for therapeutic intervention ...
  • Fusco, Nicola; Guerini-Rocco, Elena; Schultheis, Anne M.; Badve, Sunil S.; Reis-Filho, Jorge S.; Weigelt, Britta (Sage, 2015-02)
    Adenoid cystic carcinoma is a rare malignancy of exocrine glands defined by the presence of a dual population of cells (epithelial and myoepithelial cells) organized in varying combinations of cribriform, tubular, and solid ...
  • Nakshatri, Harikrishna; Sledge, George W., Jr.; Badve, Sunil; Bales, Casey; Gilley, David P.; Goswami, Chirayu; Wells, Clark D.; Guise, Theresa; Ziner, Kim W. (Office of the Vice Chancellor for Research, 2013-04-05)
    The mission of IUPUI breast cancer center is to address prevention, early detection, and treatment of breast cancer through translational projects, supportive cores, and synergistic programs. This poster details our efforts ...
  • Ross, Jeffrey S.; Badve, Sunil; Wang, Kai; Sheehan, Christine E.; Boguniewicz, Ann B.; Otto, Geoff A.; Yelensky, Roman; Lipson, Doron; Ali, Siraj; Morosini, Deborah; Chliemlecki, Juliann; Elvin, Julia A.; Miller, Vincent A.; Stephens, Philip J. (2015-05)
    Context.— Metastatic metaplastic breast carcinoma (MPBC) is an uncommon, but aggressive, tumor resistant to conventional chemotherapy. Objective.— To learn whether next-generation sequencing could identify potential ...
  • Gökmen-Polar, Yesim; Vladislav, I. Tudor; Neelamraju, Yaseswini; Janga, Sarath Chandra; Badve, Sunil (Nature, 2015-03)
    Expression of HOX transcript antisense intergenic RNA (HOTAIR), a large intergenic noncoding RNA (lincRNA), has been described as a metastases-associated lincRNA in various cancers including breast, liver and colon cancer ...
  • Nakshatri, Harikrishna; Gilley, David P.; Wells, Clark D.; Nephew, Kenneth; Radovich, Milan; Guise, Theresa; Bales, Casey; Perkins, Susan; Badve, Sunil; Vladislav, Ioan Tudor; Miller, Kathy (Office of the Vice Chancellor for Research, 2014-04-11)
    The mission of IUPUI breast cancer signature center is to address prevention, early detection, and treatment of breast cancer through translational projects, supportive cores, and synergistic programs. This poster details ...