Browsing Department of Biochemistry and Molecular Biology by Subject "macrocycles"

Browsing Department of Biochemistry and Molecular Biology by Subject "macrocycles"

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  • Trilles, Richard; Beglov, Dmitri; Chen, Qiujia; He, Hongzhen; Wireman, Randall; Reed, April; Chennamadhavuni, Spandan; Panek, James S.; Brown, Lauren E.; Vajda, Sandor; Porco, John A., Jr.; Kelley, Mark R.; Georgiadis, Millie M. (ACS, 2019)
    Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential base excision repair enzyme that is upregulated in a number of cancers, contributes to resistance of tumors treated with DNA-alkylating or -oxidizing agents, and ...

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