• Understanding the Experiences of Black Women Medical Students and Residents: A Narrative Review.. 

  Sharp, Sacha; Hixson, Ashley; Stumpff, Julia C; Williamson, Francesca (2022-06-14)

  Background: Few research studies examine medical students and residents with intersectional identities. In the emerging literature, data on Black women’s experiences may be misrepresented and misinterpreted as studies ...
• Moving Beyond Cultural Competence Toward Cultural Humility and the Delivery of Equitable Patient-Centered Care 

  Maldonado, Maria; Dupras, Denise; Sotto-Santiago, Sylk (2019)

  In the Accreditation Council on Graduate Medical Education’s (ACGME) 2016 national report of the Clinical Learning Environment (CLE) Review, it was reported that across most CLEs, education and training on health care ...
• Culturally Appropriate & Socially Responsive Care [CASRC] Thread 

  Price, Mary; Sotto-Santiago, Sylk; Lazarus, Ken; Christy, Lisa (2018)

  Medical Education Objectives for the Social Science Thread (Now:Culturally Appropriate & Socially Responsive Care [CASRC] Thread): 1) The primary goal of the CASRC Thread is not to develop specific sessions for presentation ...
• Cultural Factors in Women’s Health in Eswantini: The PEN-3 Model 

  Murray, Bethany A. (U-RISE, 2022)
• Understanding the experiences of Black women medical students and residents: A narrative review. 

  Sharp, Sacha; Hixson, Ashley; Stumpff, Julia C.; Williamson, Francesca (2022-04-23)

  Few research studies examine medical students and residents with intersectional identities. In the emerging literature, data on Black women’s experiences may be misrepresented and misinterpreted as studies aggregate data ...
• The role of endoscopic therapy in the minimally invasive management of pancreatic necrosis 

  Easler, Jeffrey James (Korean Association of Internal Medicine, 2021-01)

  Pancreatic necrosis is among the most frequently encountered local complications of acute pancreatitis and associates with severe disease. Infected pancreatic necrosis further enhances the risk for morbidity and mortality. ...
• Phosphate Binders and Non-Phosphate Effects in the Gastrointestinal Tract 

  Biruete, Annabel; Hill Gallant, Kathleen M.; Lindemann, Stephen R.; Wiese, Gretchen; Chen, Neal; Moe, Sharon (Elsevier, 2020-01)

  Phosphate binders are commonly prescribed in patients with end-stage kidney disease to prevent and treat hyperphosphatemia. These binders are usually associated with gastrointestinal distress, may bind molecules other than ...
• Postoperative delirium is associated with increased plasma neurofilament light 

  Casey, Cameron P.; Lindroth, Heidi; Mohanty, Rosaleena; Farahbakhsh, Zahra; Ballweg, Tyler; Twadell, Sarah; Miller, Samantha; Krause, Bryan; Prabhakaran, Vivek; Blennow, Kaj; Zetterberg, Henrik; Sanders, Robert D. (Oxford University Press, 2020-01)

  While delirium is associated with cognitive decline and dementia, there is limited evidence to support causality for this relationship. Clarification of how delirium may cause cognitive decline, perhaps through evidence ...
• Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats 

  Cheng, Tik-Chee; Philip, Jennifer L.; Tabima, Diana M.; Kumari, Santosh; Yakubov, Bakhtiyor; Frump, Andrea L.; Hacker, Timothy A.; Bellofiore, Alessandro; Li, Rongbo; Sun, Xin; Goss, Kara N.; Lahm, Tim; Chesler, Naomi C. (American Physiological Society, 2020-12)

  Although women are more susceptible to pulmonary arterial hypertension (PAH) than men, their right ventricular (RV) function is better preserved. Estrogen receptor-α (ERα) has been identified as a likely mediator for ...
• A 64-Year-Old Man with Low Back Pain Due to Clostridium perfringens Lumbar Discitis 

  Bhatt, Harshil; Singh, Sandeep (International Scientific Information, 2021-01-22)

  Lumbar discitis caused by Clostridium perfringens is extremely rare. There have only been 7 published cases of confirmed discitis caused by Clostridium perfringens. We write this report to underscore this unusual relationship ...
• Integrative analysis of histopathological images and chromatin accessibility data for estrogen receptor-positive breast cancer 

  Xu, Siwen; Lu, Zixiao; Shao, Wei; Yu, Christina Y.; Reiter, Jill L.; Feng, Qianjin; Feng, Weixing; Huang, Kun; Liu, Yunlong (BMC, 2020-12-28)

  Background: Existing studies have demonstrated that the integrative analysis of histopathological images and genomic data can be used to better understand the onset and progression of many diseases, as well as identify new ...
• A pan-kidney cancer study identifies subtype specific perturbations on pathways with potential drivers in renal cell carcinoma 

  Zhan, Xiaohui; Liu, Yusong; Yu, Christina Y.; Wang, Tian‑Fu; Zhang, Jie; Ni, Dong; Huang, Kun (BMC, 2020-12-28)

  Background: Renal cell carcinoma (RCC) is a complex disease and is comprised of several histological subtypes, the most frequent of which are clear cell renal cell carcinoma (ccRCC), papillary renal cell carcinoma (PRCC) ...
• Self-Efficacy for Adoption and Maintenance of Exercise Among Fibromyalgia Patients: A Pilot Study 

  Scioli-Salter, Erica R.; Smith, Brian N.; McSheffrey, Savannah; Bair, Matthew J.; Sillice, Marie A.; Driscoll, Mary; Higgins, Diana M.; Allsup, Kelly; Amalathas, Aneline; Gerber, Megan R. (Sage, 2020-01)

  Objective. While multimodal treatment approaches for fibromyalgia (FM), incorporating exercise, have been found most effective, information about factors associated with exercise adoption and maintenance is lacking. Design, ...
• Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes 

  Romanoski, Casey E.; Qi, Xinshuai; Sangam, Shreya; Vanderpool, Rebecca R.; Stearman, Robert S.; Conklin, Austin; Gonzalez-Garay, Manuel; Rischard, Franz; Ayon, Ramon J.; Wang, Jian; Simonson, Tatum; Babicheva, Aleksandra; Shi, Yinan; Tang, Haiyang; Makino, Ayako; Kanthi, Yogendra; Geraci, Mark W.; Garcia, Joe G.N.; Yuan, Jason X.-J.; Desai, Ankit A. (Sage, 2020-12-07)

  Using RNAseq, we identified a 61 gene-based circulating transcriptomic profile most correlated with four indices of pulmonary arterial hypertension severity. In an independent dataset, 13/61 (21%) genes were differentially ...
• Integrating Prevention of Mother-to-Child Transmission of HIV Care into General Maternal Child Health Care in Western Kenya 

  Berlacher, Michelle; Mercer, Timothy; Apondi, Edith O.; Mwangi, Winfred; Were, Edwin; McHenry, Megan S. (Global Health and Education Projects, 2021)

  Background: Health systems integration is becoming increasingly important as the global health community transitions from acute, disease-specific health programming to models of care built for chronic diseases, primarily ...
• Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine 

  Agarwal, Rajiv; Kolkhof, Peter; Bakris, George; Bauersachs, Johann; Haller, Hermann; Wada, Takashi; Zannad, Faiez (Oxford University Press, 2021-01-07)

  This review covers the last 80 years of remarkable progress in the development of mineralocorticoid receptor (MR) antagonists (MRAs) from synthesis of the first mineralocorticoid to trials of nonsteroidal MRAs. The MR is ...
• Neurohormonal Regulation of IKs in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death 

  Shugg, Tyler; Hudmon, Andy; Overholser, Brian R. (American Heart Association, 2020-09-15)

  Heart failure (HF) results in sustained alterations in neurohormonal signaling, including enhanced signaling through the sympathetic nervous system and renin-angiotensin-aldosterone system pathways. While enhanced sympathetic ...
• Genetic ablation of Cullin-RING E3 ubiquitin ligase 7 restrains pressure overload-induced myocardial fibrosis 

  Anger, Melanie; Scheufele, Florian; Ramanujam, Deepak; Meyer, Kathleen; Nakajima, Hidehiro; Field, Loren J.; Engelhardt, Stefan; Sarikas, Antonio (PLOS, 2020-12-22)

  Fibrosis is a pathognomonic feature of structural heart disease and counteracted by distinct cardioprotective mechanisms, e.g. activation of the phosphoinositide 3-kinase (PI3K) / AKT pro-survival pathway. The Cullin-RING ...
• Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer 

  Voss, Martin H.; Gordon, Michael S.; Mita, Monica; Rini, Brian; Makker, Vicky; Macarulla, Teresa; Smith, David C.; Cervantes, Andrés; Puzanov, Igor; Pili, Roberto; Wang, Ding; Jalal, Shadia; Pant, Shubham; Patel, Manish R.; Neuwirth, Rachel l.; Enke, Aaron; Shou, Yaping; Sedarati, Farhad; Faller, Douglas V.; Burris, Howard A., III (Springer Nature, 2020-11)

  Background: This Phase 1 dose-escalation/expansion study assessed safety/tolerability of sapanisertib, an oral, highly selective inhibitor of mTORC1/mTORC2, in advanced solid tumours. Methods: Eligible patients received ...
• Mutational and phenotypic characterization of hereditary hemorrhagic telangiectasia 

  Shovlin, Claire L.; Simeoni, Ilenia; Downes, Kate; Frazer, Zoe C.; Megy, Karyn; Bernabeu-Herrero, Maria E.; Shurr, Abigail; Brimley, Jennifer; Patel, Dilipkumar; Kell, Loren; Stephens, Jonathan; Turbin, Isobel G.; Aldred, Micheala A.; Penkett, Christopher J.; Ouwehand, Willem H.; Jovine, Luca; Turro, Ernest (American Society of Hematology, 2020-10-22)

  Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia. Care delivery for HHT patients is impeded by the need for laborious, repeated phenotyping and gaps in knowledge regarding the ...

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