• Clinical and Genetic Risk Factors for Adverse Metabolic Outcomes in North American Testicular Cancer Survivors 

  Abu Zaid, Mohammad; Gathirua-Mwangi, Wambui G.; Fung, Chunkit; Monahan, Patrick O.; El-Charif, Omar; Williams, Annalynn M.; Feldman, Darren R.; Hamilton, Robert J.; Vaughn, David J.; Beard, Clair J.; Cook, Ryan; Althouse, Sandra; Ardeshir-Rouhani-Fard, Shirin; Dinh, Paul C., Jr.; Sesso, Howard D.; Einhorn, Lawrence H.; Fossa, Sophie D.; Travis, Lois B. (National Comprehensive Cancer Network, 2018-03)

  Background: Testicular cancer survivors (TCS) are at significantly increased risk for cardiovascular disease (CVD), with metabolic syndrome (MetS) an established risk factor. No study has addressed clinical and genetic ...
• The Small Conductance Calcium Activated Potassium Current Modulates the Ventricular Escape Rhythm in Normal Rabbit Hearts 

  Wan, Juyi; Chen, Mu; Wang, Zhuo; Everett, Thomas H., IV; Rubart-von der Lohe, Michael; Shen, Changyu; Qu, Zhilin; Weiss, James N.; Boyden, Penelope A.; Chen, Peng-Sheng (Elsevier, 2018)

  Background The apamin-sensitive small-conductance calcium-activated K (SK) current (IKAS) modulates automaticity of the sinus node; IKAS blockade by apamin causes sinus bradycardia. Objective To test the hypothesis ...
• La recherche réalisée par les pharmaciens d’hôpitaux : une composante indispensable de la pratique quotidienne ou une attente irréaliste? 

  Tisdale, James E. (Canadian Society of Hospital Pharmacists, 2018-03)
• Protein-Specific Features Associated with Variability in Human Antibody Responses to Plasmodium falciparum Malaria Antigens 

  Liu, Eugene W.; Skinner, Jeff; Tran, Tuan M.; Kumar, Krishan; Narum, David L.; Jain, Aarti; Ongoiba, Aissata ba; Traoré, Boubacar; Felgner, Philip L.; Crompton, Peter D. (American Society of Tropical Medicine and Hygiene, 2018-01)

  The magnitude of antibody responses varies across the individual proteins that constitute any given microorganism, both in the context of natural infection and vaccination with attenuated or inactivated pathogens. The ...
• Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial 

  Pierson, Rebecca C.; Gufford, Brandon T.; Desta, Zeruesenay; Eadon, Michael T. (Future Medicine, 2017-06)

  Pharmacogenomic testing has become increasingly widespread. However, there remains a need to bridge the gap between test results and providers lacking the expertise required to interpret these results. The Indiana Genomics ...
• Research Conducted by Hospital Pharmacists: Integral Component of Daily Practice or Unrealistic Expectation? 

  Tisdale, James E. (Canadian Society of Hospital Pharmacists, 2018-03)
• Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer 

  Andersen, Dana K.; Korc, Murray; Petersen, Gloria M.; Eibl, Guido; Li, Donghui; Rickels, Michael R.; Chari, Suresh T.; Abbruzzese, James L. (American Diabetes Association, 2017-05)

  The relationships between diabetes and pancreatic ductal adenocarcinoma (PDAC) are complex. Longstanding type 2 diabetes (T2DM) is a risk factor for pancreatic cancer, but increasing epidemiological data point to PDAC as ...
• Comparison of Commercial and Self-Initiated Weight Loss Programs in People With Prediabetes: A Randomized Control Trial 

  Marrero, David G.; Palmer, Kelly N. B.; Phillips, Erin O.; Miller-Kovach, Karen; Foster, Gary D.; Saha, Chandan K. (American Public Health Association, 2016-05)

  To determine if a widely available weight-management program (Weight Watchers) could achieve sufficient weight loss in persons with prediabetes compared with a Diabetes Prevention Program-based individual counseling program ...
• Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: a brain magnetic resonance imaging pilot study 

  Chen, Bihong T.; Sethi, Sean K.; Jin, Taihao; Patel, Sunita K.; Ye, Ningrong; Sun, Can-Lan; Rockne, Russell C.; Haacke, E. Mark; Root, James C.; Saykin, Andrew J.; Ahles, Tim A.; Holodny, Andrei I.; Prakash, Neal; Mortimer, Joanne; Waisman, James; Yuan, Yuan; Somlo, George; Li, Daneng; Yang, Richard; Tan, Heidi; Katheria, Vani; Morrison, Rachel; Hurria, Arti (BMC, 2018-05-02)

  BACKGROUND: Cognitive decline is among the most feared treatment-related outcomes of older adults with cancer. The majority of older patients with breast cancer self-report cognitive problems during and after chemotherapy. ...
• Supporting teams to optimize function and independence in Veterans: a multi-study program and mixed methods protocol 

  Wang, Virginia; Allen, Kelli; Van Houtven, Courtney H.; Coffman, Cynthia; Sperber, Nina; Mahanna, Elizabeth P.; Colón-Emeric, Cathleen; Hoenig, Helen; Jackson, George L.; Damush, Teresa M.; Price, Erika; Hastings, Susan N. (BMC, 2018-04-20)

  BACKGROUND: Successful implementation of new clinical programs depends on effectively establishing, reorganizing, or enhancing team structures and processes to coordinate the work of individuals who are interdependent ...
• Comparing adenoma and polyp miss rates for total underwater colonoscopy versus standard CO2: a randomized controlled trial using a tandem colonoscopy approach 

  Anderson, Joseph C.; Kahi, Charles J.; Sullivan, Andrew; MacPhail, Margaret; Garcia, Jonathan; Rex, Douglas K. (Elsevier, 2018)

  Background and Aims Although water exchange may improve adenoma detection when compared to CO2, it is unclear whether water is a better medium to fill the lumen during withdrawal and visualize the mucosa. Total underwater ...
• Diagnostic Yield and Miss Rate of EndoRings in an Organized Colorectal Cancer Screening Program: the SMART (Study Methodology for ADR-Related Technology) Trial 

  Hassan, Cesare; Senore, Carlo; Manes, Gianpiero; Fuccio, Lorenzo; Iacopini, Federico; Ricciardiello, Luigi; Anderloni, Andrea; Frazzoni, Leonardo; Ballanti, Riccardo; de Nucci, Germana; Colussi, Dora; Radaelli, Davide; Lorenzetti, Roberto; Devani, Massimo; Arena, Ilaria; Grossi, Cristina; Andrei, Fabio; Balestrazzi, Eleonora; Sharma, Prateek; Rex, Douglas K.; Repici, Alessandro (Elsevier, 2018)

  Background and aims The add-on EndoRings has been claimed to improve adenoma detection at colonoscopy, but available data are inconsistent. When testing a new technology, parallel and crossover methodologies measure ...
• High‐speed Intraoperative Assessment of Breast Tumor Margins by Multimodal Ultrasound and Photoacoustic Tomography 

  Lu, Rui; Lan, Lu; Xia, Yan; Wang, Pu; Han, Linda K.; Dunnington, Gary L.; Obeng-Gyasi, Samilia; Sandusky, George E.; Medley, Jennifer A.; Crook, Susan T.; Cheng, Ji-Xin (Wiley, 2018)

  Conventional methods for breast tumor margins assessment need a long turnaround time, which may lead to re‐operation for patients undergoing lumpectomy surgeries. Photoacoustic tomography (PAT) has been shown to visualize ...
• Identification of N-benzyltetrahydroisoquinolines as novel anti-neuroinflammatory agents 

  Gabet, Brian; Kuo, Ping-Chang; Fuentes, Steven; Patel, Yamini; Adow, Ahmed; Alsakka, Mary; Avila, Paula; Beam, Teri; Yen, Jui-Hung; Brown, Dennis A. (Elsevier, 2018-11)

  A series of simplified berberine analogs was designed, synthesized, and evaluated for anti-inflammatory activity. SAR studies identified N-benzyltetrahydroisoquinoline 7d as a potent berberine analog. 7d suppressed LPS-induced ...
• MERS coronavirus outbreak: Implications for emerging viral infections 

  Al-Omari, Awad; Rabaan, Ali A.; Salih, Samer; Al-Tawfiq, Jaffar A.; Memish, Ziad A. (Elsevier, 2018)

  In September 2012, a novel coronavirus was isolated from a patient who died in Saudi Arabia after presenting with acute respiratory distress and acute kidney injury. Analysis revealed the disease to be due to a novel virus ...
• Triggered Palliative Care for Late-stage Dementia: a Pilot Randomized Trial 

  Hanson, Laura C.; Kistler, Christine E.; Lavin, Kyle; Gabriel, Stacey L.; Ernecoff, Natalie C.; Lin, Feng-Chang; Sachs, Greg A.; Mitchell, Susan L. (Elsevier, 2018)

  Context Persons with late-stage dementia have limited access to palliative care. Objective To test dementia-specific specialty palliative care triggered by hospitalization. Methods This pilot randomized controlled ...
• Leveraging the power of partnerships: spreading the vision for a population health care delivery model in western Kenya 

  Mercer, Tim; Gardner, Adrian; Andama, Benjamin; Chesoli, Cleophas; Christoffersen-Deb, Astrid; Dick, Jonathan; Einterz, Robert; Gray, Nick; Kimaiyo, Sylvester; Kamano, Jemima; Maritim, Beryl; Morehead, Kirk; Pastakia, Sonak; Ruhl, Laura; Songok, Julia; Laktabai, Jeremiah (BMC, 2018-05-08)

  BACKGROUND: The Academic Model Providing Access to Healthcare (AMPATH) has been a model academic partnership in global health for nearly three decades, leveraging the power of a public-sector academic medical center and ...
• Developing the Agile Implementation Playbook for Integrating Evidence-Based Health Care Services into Clinical Practice 

  Boustani, Malaz A.; van der Marck, Marjolein A.; Adams, Nadia; Azar, Jose M.; Holden, Richard J.; Vollmar, Horst C.; Wang, Sophia; Williams, Christopher; Alder, Catherine; Suarez, Shelley; Khan, Babar; Zarzaur, Ben; Fowler, Nicole R.; Overley, Ashley; Solid, Craig A.; Gatmaitan, Alfonso (Wolters Kluwer, 2018-10)

  Problem: Despite the more than $32 billion the National Institutes of Health has invested annually, evidence-based health care services are not reliably implemented, sustained, or distributed in health care delivery ...
• Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization 

  Zhang, Hanfang; Hudson, Farlyn Z.; Xu, Zhimin; Tritz, Rebekah; Rojas, Modesto; Patel, Chintan; Haigh, Stephen B.; Bordán, Zsuzsanna; Ingram, David A.; Fulton, David J.; Weintraub, Neal L.; Caldwell, Ruth B.; Stansfield, Brian K. (Association for Research in Vision and Ophthalmology, 2018-05-01)

  Purpose: Neurofibromatosis type 1 (NF1) is the result of inherited mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. Eye manifestations are common in NF1 with recent reports describing ...
• Endothelial nitric oxide synthase genotype is associated with pulmonary hypertension severity in left heart failure patients 

  Duarte, Julio D.; Kansal, Mayank; Desai, Ankit A.; Riden, Katherine; Arwood, Meghan J.; Yacob, Alex A.; Stamos, Thomas D.; Cavallari, Larisa H.; Zamanian, Roham T.; Shah, Sanjiv J.; Machado, Roberto F. (Sage, 2018-04)

  The biological mechanisms behind the development of pulmonary hypertension in the setting of left heart failure (HF-PH), including combined pre- and post-capillary pulmonary hypertension (Cpc-PH), remains unclear. This ...

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