Department of Biology

 

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Recent Submissions

  • Policastro, Robert A.; Raborn, R. Taylor; Brendel, Volker P.; Zentner, Gabriel E. (CSHL Press, 2020-06)
    Accurate mapping of transcription start sites (TSSs) is key for understanding transcriptional regulation. However, current protocols for genome-wide TSS profiling are laborious and/or expensive. We present Survey of ...
  • Robison, Jennifer D.; Berbari, Nicolas F.; Rao, Anusha S. (American Society for Microbiology, 2020-01)
    This study explores whether integrating multicultural content within a genetics laboratory course affected students' awareness of diversity and their perceptions of scientists' identities. Genetics laboratory curricula ...
  • Eriksson, T.; Picard, C.J. (Wageningen Academic, 2021)
    This review will summarise existing tools and resources and highlight areas of focus for the insects as food and feed industry for the production of insects as alternative protein sources. By applying knowledge gained from ...
  • Fang, Wei; Wang, Xianzhong (Springer, 2020-03)
    Background Invasive species affect community dynamics and ecosystem functions, but the mechanisms of their impacts are poorly understood. Hypotheses on invasion impact range from Superior Competitor to Novel Function, ...
  • Jasso, Kalene R.; Kamba, Tisianna K.; Zimmerman, Arthur D.; Bansal, Ruchi; Engle, Staci E.; Everett, Thomas; Wu, Chang-Hung; Kulaga, Heather; Reed, Randal R.; Berbari, Nicolas F.; McIntyre, Jeremy C. (Wiley, 2021-08)
    Cilia on neurons play critical roles in both the development and function of the central nervous system (CNS). While it remains challenging to elucidate the precise roles for neuronal cilia, it is clear that a subset of ...
  • Chen, Yan; Branicki, Wojciech; Walsh, Susan; Nothnagel, Michael; Kayser, Manfred; Liu, Fan (Elsevier, 2021-01)
    Predicting appearance phenotypes from genotypes is relevant for various areas of human genetic research and applications such as genetic epidemiology, human history, anthropology, and particularly in forensics. Many ...
  • Katsara, Maria-Alexandra; Branicki, Wojciech; Pośpiech, Ewelina; Hysi, Pirro; Walsh, Susan; Kayser, Manfred; Nothnagel, Michael; VISAGE Consortium (Elsevier, 2021-01)
    The prediction of appearance traits by use of solely genetic information has become an established approach and a number of statistical prediction models have already been developed for this purpose. However, given limited ...
  • Simpson, Stefanie; Preston, Daniel; Schwerk, Christian; Schroten, Horst; Blazer-Yost, Bonnie (American Physiological Society, 2019-11)
    The choroid plexus (CP), composed of capillaries surrounded by a barrier epithelium, is the main producer of cerebrospinal fluid (CSF). The CP epithelium regulates the transport of ions and water between the blood and the ...
  • Wang, Qizhao; Zhuang, Pei; Huang, Haoliang; Li, Liang; Liu, Liang; Webber, Hannah C.; Dalal, Roopa; Siew, Leonard; Fligor, Clarisse M.; Chang, Kun-Che; Nahmou, Michael; Kreymerman, Alexander; Sun, Yang; Meyer, Jason S.; Goldberg, Jeffrey Louis; Hu, Yang (SfN, 2020-05-13)
    Optic neuropathies are a group of optic nerve (ON) diseases caused by various insults including glaucoma, inflammation, ischemia, trauma, and genetic deficits, which are characterized by retinal ganglion cell (RGC) death ...
  • McGrath, Jamis; Tung, Chun-Yu; Liao, Xiayi; Belyantseva, Inna A.; Roy, Pallabi; Chakraborty, Oisorjo; Li, Jinan; Berbari, Nicolas F.; Faaborg-Andersen, Christian C.; Barzik, Melanie; Bird, Jonathan E.; Zhao, Bo; Balakrishnan, Lata; Friedman, Thomas B.; Perrin, Benjamin J. (Elsevier, 2021-03)
    Stereocilia on auditory sensory cells are actin-based protrusions that mechanotransduce sound into an electrical signal. These stereocilia are arranged into a bundle with three rows of increasing length to form a staircase-like ...
  • Eriksson, T.; Andere, A. A.; Kelstrup, H.; Emery, V. J.; Picard, C. J. (Wageningen, 2020)
    The yellow mealworm, the larval stage of the darkling beetle Tenebrio molitor, shows great promise as an alternative source of animal protein. Herein we present the 312 Mb draft genome assembled using 10x Genomics linked-read ...
  • Robertson, Morgan A.; Padgett, Leah R.; Fine, Jonathan A.; Chopra, Gaurav; Mastracci, Teresa L. (Taylor & Francis, 2020-07-25)
    Type 1 diabetes (T1D) is a disease characterized by destruction of the insulin-producing beta cells. Currently, there remains a critical gap in our understanding of how to reverse or prevent beta cell loss in individuals ...
  • Hochstetler, Alexandra E.; Smith, Hillary M.; Preston, Daniel C.; Reed, Makenna M.; Territo, Paul R.; Shim, Joon W.; Fulkerson, Daniel; Blazer-Yost, Bonnie L. (American Society for Clinical Investigation, 2020-09-17)
    Hydrocephalus is a serious condition that impacts patients of all ages. The standards of care are surgical options to divert, or inhibit production of, cerebrospinal fluid; to date, there are no effective pharmaceutical ...
  • Sarmah, Swapnalee; Sales Cadena, Marilia Ribeiro; Cadena, Pabyton Gonçalves; Marrs, James A. (MDPI, 2020-08-08)
    Marijuana and opioid addictions have increased alarmingly in recent decades, especially in the United States, posing threats to society. When the drug user is a pregnant mother, there is a serious risk to the developing ...
  • Illouz, Tomer; Biragyn, Arya; Frenkel‑Morgenstern, Milana; Weissberg, Orly; Gorohovski, Alessandro; Merzon, Eugene; Green, Ilan; Iulita, Florencia; Flores-Aguilar, Lisi; del Mar Dierssen Sotos, Maria; De Toma, Ilario; Lifshitz, Herziba; Antonarakis, Stylianos E.; Yu, Eugene; Herault, Yann; Potier, Marie-Claude; Botté, Alexandra; Roper, Randall; Sredni, Benjamin; Sarid, Ronit; London, Jacqueline; Mobley, William; Strydom, Andre; Okun, Eitan (Springer, 2021)
    The current SARS-CoV-2 outbreak, which causes COVID-19, is particularly devastating for individuals with chronic medical conditions, in particular those with Down Syndrome (DS) who often exhibit a higher prevalence of ...
  • Davidson, Rebecca K.; Himes, Evan R.; Takigawa, Shinya; Chen, Andy; Horn, M. Ryne; Meijome, Tomas; Wallace, Joseph M.; Kacena, Melissa A.; Yokota, Hiroki; Nguyen, Andrew V.; Li, Jiliang (Public Library of Science, 2020-07-30)
    Signal Transducer and Activator of Transcription 3 (STAT3) has recently been shown to be involved in bone development and has been implicated in bone diseases, such as Job’s Syndrome. Bone growth and changes have been known ...
  • Peng, Kang; Radivojac, Predrag; Vucetic, Slobodan; Dunker, A. Keith; Obradovic, Zoran (BioMed Central, 2006-04-17)
    Background Due to the functional importance of intrinsically disordered proteins or protein regions, prediction of intrinsic protein disorder from amino acid sequence has become an area of active research as witnessed in ...
  • Willger, Sven D.; Puttikamonkul, Srisombat; Kim, Kwang-Hyung; Burritt, James B.; Grahl, Nora; Metzler, Laurel J.; Barbuch, Robert; Bard, Martin; Lawrence, Christopher B.; Cramer Jr., Robert A. (PLOS, 2008-11-07)
    At the site of microbial infections, the significant influx of immune effector cells and the necrosis of tissue by the invading pathogen generate hypoxic microenvironments in which both the pathogen and host cells must ...
  • McGrath, Jamis; Perrin, Benjamin J. (Elsevier, 2020-02)
    Mechanosensory bundles on auditory sensory cells are composed of stereocilia that grow in rows of decreasing height. This pattern depends on the specification of the eventual tallest row, then the assignment of distinct ...
  • Westmoreland, Jim; Ma, Wenjian; Yan, Yan; Van Hulle, Kelly; Malkova, Anna; Resnick, Michael A. (PLOS, 2009-09-18)
    Resection of DNA double-strand break (DSB) ends is generally considered a critical determinant in pathways of DSB repair and genome stability. Unlike for enzymatically induced site-specific DSBs, little is known about ...

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