• Validating the experimental approaches for electrophysiological recording of hypothalamic POMC neurons and in vivo insulin receptor knockdown 

  Yan, Shijun; Vieira-de-Abreu, Adriana; Reilly, Austin M.; Paranjape, Sachin A.; Accili, Domenico; Chan, Owen; Ren, Hongxia (2019-04-26)
• Premenarchal Girls' Genital Examination Experiences 

  Robbins, Cynthia L.; Fortenberry, J. Dennis; Roth, Alexis M.; Ott, Mary A. (Elsevier, 2012-08)

  Purpose To explore girls' experiences having an external genital examination during early adolescence. Methods Ten premenarchal girls were interviewed about their experiences receiving an external genital examination ...
• Th9 immunodeficiency in Hyper IgE syndrome patients 

  Olson, Matthew R.; Kaplan, Mark H. (Elsevier, 2018)
• A Nationwide Study Comparing Knowledge and Beliefs about HPV among Female Students before and after HPV Vaccination 

  Wong, Li Ping; Alias, Haridah; Sam, I-Ching; Zimet, Gregory D. (Elsevier, 2018)

  Study Objective To assess the knowledge and beliefs regarding HPV and the HPV vaccine among girls before and after vaccination in the Malaysian HPV Immunisation Programme. Design A nationwide longitudinal survey. ...
• Neurodevelopmental Outcomes at Two Years of Age for Premature Infants Diagnosed With Neonatal Obstructive Sleep Apnea 

  Bandyopadhyay, Anuja; Harmon, Heidi; Slaven, James E.; Daftary, Ameet S. (American Academy of Sleep Medicine, 2017-11-15)

  STUDY OBJECTIVES: Neurocognitive deficits have been shown in school-aged children with sleep apnea. The effect of obstructive sleep apnea (OSA) on the neurodevelopmental outcome of preterm infants is unknown. METHODS: A ...
• Big data in healthcare - the promises, challenges and opportunities from a research perspective: A case study with a model database 

  Adibuzzaman, Mohammad; DeLaurentis, Poching; Hill, Jennifer; Benneyworth, Brian D. (AMIA, 2018-04-16)

  Recent advances in data collection during routine health care in the form of Electronic Health Records (EHR), medical device data (e.g., infusion pump informatics, physiological monitoring data, and insurance claims data, ...
• Clinical Comparison of Retinopathy-Positive and Retinopathy-Negative Cerebral Malaria 

  Villaverde, Chandler; Namazzi, Ruth; Shabani, Estela; Opoka, Robert O.; John, Chandy C. (American Society of Tropical Medicine and Hygiene, 2017-05)

  AbstractCerebral malaria (CM) is a severe and often lethal complication of falciparum malaria. A classic malaria retinopathy is seen in some (retinopathy-positive [RP]) children but not others (retinopathy-negative [RN]), ...
• Chewing the Fat: A Metabolic Role for Ldb1 Beyond the Pancreas? 

  Sims, Emily K. (Endocrine Society, 2017-04-29)
• SLAMF6 in health and disease: Implications for therapeutic targeting 

  Yigit, Burcu; Wang, Ninghai; Herzog, Roland W.; Terhorst, Cox (Elsevier, 2018)
• Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications 

  Dobrian, A. D.; Morris, M. A.; Taylor-Fishwick, D. A.; Holman, T. R.; Imai, Y.; Mirmira, Raghu G.; Nadler, J. L. (Elsevier, 2018)

  12-lipoxygenase (12-LOX) is one of several enzyme isoforms responsible for the metabolism of arachidonic acid and other poly-unsaturated fatty acids to both pro- and anti-inflammatory lipid mediators. Mounting evidence has ...
• T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy 

  Scheible, Kristin M.; Emo, Jason; Laniewski, Nathan; Baran, Andrea M.; Peterson, Derick R.; Holden-Wiltse, Jeanne; Bandyopadhyay, Sanjukta; Straw, Andrew G.; Huyck, Heidie; Ashton, John M.; Tripi, Kelly Schooping; Arul, Karan; Werner, Elizabeth; Scalise, Tanya; Maffett, Deanna; Caserta, Mary; Ryan, Rita M.; Reynolds, Anne Marie; Ren, Clement L.; Topham, David J.; Mariani, Thomas J.; Pryhuber, Gloria S. (American Society for Clinical Investigation, 2018-02-22)

  The inverse relationship between gestational age at birth and postviral respiratory morbidity suggests that infants born preterm (PT) may miss a critical developmental window of T cell maturation. Despite a continued ...
• Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway 

  Palam, Lakshmi Reddy; Mali, Raghuveer Singh; Ramdas, Baskar; Srivatsan, Sridhar Nonavinkere; Visconte, Valeria; Tiu, Ramon V.; Vanhaesebroeck, Bart; Roers, Axel; Gerbaulet, Alexander; Xu, Mingjiang; Janga, Sarath Chandra; Takemoto, Clifford M.; Paczesny, Sophie; Kapur, Reuben (American Society for Clinical Investigation, 2018-02-22)

  Mutations in KIT and TET2 are associated with myeloid malignancies. We show that loss of TET2-induced PI3K activation and -increased proliferation is rescued by targeting the p110α/δ subunits of PI3K. RNA-Seq revealed a ...
• Progression of Lung Disease in Preschool Patients with Cystic Fibrosis 

  Stanojevic, Sanja; Davis, Stephanie D.; Retsch-Bogart, George t; Webster, Hailey; Davis, Miriam; Johnson, Robin C.; Jensen, Renee; Pizarro, Maria Ester; Kane, Mica; Clem, Charles C.; Schornick, Leah; Subbarao, Padmaja; Ratjen, Felix A. (American Thoracic Society, 2017-05-01)

  RATIONALE: Implementation of intervention strategies to prevent lung damage in early cystic fibrosis (CF) requires objective outcome measures that capture and track lung disease. OBJECTIVES: To define the utility ...
• Oral Food Challenge Failures Among Foods Restricted Due to Atopic Dermatitis 

  Eapen, A. A.; Kloepfer, Kirsten M.; Leickly, Frederick E.; Slaven, James E.; Vitalpur, Girish (Elsevier, 2018)

  BACKGROUND Recent studies have suggested that removing foods from the diet to manage atopic dermatitis (AD), based on positive allergy tests, may lead to immediate allergic reactions on reintroduction of that food. O ...
• Novel pathogenic variants in filamin C identified in pediatric restrictive cardiomyopathy 

  Schubert, Jeffrey; Tariq, Muhammad; Geddes, Gabrielle; Kindel, Steven; Miller, Erin M.; Ware, Stephanie M. (Wiley, 2018)

  Restrictive cardiomyopathy (RCM) is a rare and distinct form of cardiomyopathy characterized by normal ventricular chamber dimensions, normal myocardial wall thickness, and preserved systolic function. The abnormal myocardium, ...
• Creation and validation of tool to assess resident competence in neonatal resuscitation 

  Kane, Sara K.; Lorant, Diane E. (Elsevier, 2018)

  Background The American Board of Pediatrics requires that pediatricians be able to initiate stabilization of a newborn. After residency, 45% of general pediatricians routinely attend deliveries. However, there is no ...
• Structure and Functions of Pediatric Aerodigestive Programs: A Consensus Statement 

  Boesch, R. Paul; Balakrishnan, Karthik; Acra, Sari; Benscoter, Dan T.; Cofer, Shelagh A.; Collaco, Joseph M.; Dahl, John P.; Daines, Cori L.; DeAlarcon, Alessandro; DeBoer, Emily M.; Deterding, Robin R.; Friedlander, Joel A.; Gold, Benjamin D.; Grothe, Rayna M.; Hart, Catherine K.; Kazachkov, Mikhail; Lefton-Greif, Maureen A.; Miller, Claire Kane; Moore, Paul E.; Pentiuk, Scott; Peterson-Carmichael, Stacey; Piccione, Joseph; Prager, Jeremy D.; Putnam, Philip E.; Rosen, Rachel; Rutter, Michael J.; Ryan, Matthew J.; Skinner, Margaret L.; Torres-Silva, Cherie; Wootten, Christopher T.; Zur, Karen B.; Cotton, Robin T.; Wood, Robert E. (AAP, 2018-03)

  Aerodigestive programs provide coordinated interdisciplinary care to pediatric patients with complex congenital or acquired conditions affecting breathing, swallowing, and growth. Although there has been a proliferation ...
• Mutant and wild-type p53 form complexes with p73 upon phosphorylation by the kinase JNK 

  Wolf, Eric R.; McAtarsney, Ciaran P.; Bredhold, Kristin E.; Kline, Amber M.; Mayo, Lindsey D. (2018-04)

  The transcription factors p53 and p73 are critical to the induction of apoptotic cell death, particularly in response to cell stress that activates c-Jun N-terminal kinase (JNK). Mutations in the DNA-binding domain of p53, ...
• Retention and adherence: global challenges for the long-term care of adolescents and young adults living with HIV 

  Enane, Leslie A.; Vreeman, Rachel C.; Foster, Caroline (Wolters Kluwer, 2018-05)

  Purpose of review Adolescents living with HIV are the only age group with increasing HIV mortality at a time of global scale-up of access to antiretroviral therapy (ART). As a ‘treat all’ strategy is implemented worldwide, ...
• Care Coordination for Children With Medical Complexity: Whose Care Is It, Anyway? 

  Kuo, Dennis Z.; McAllister, Jeanne W.; Rossignol, Lisa; Turchi, Renee M.; Stille, Christopher J. (AAP, 2018-03)

  Children with medical complexity (CMC) have multiple chronic conditions and require an array of medical- and community-based providers. Dedicated care coordination is increasingly seen as key to addressing the fragmented ...

View more