• Physician Intervention to Positive Depression Screens Among Adolescents in Primary Care 

  Aalsma, Matthew C.; Zerr, Ashley M.; Etter, Dillon J.; Ouyang, Fangqian; Gilbert, Amy Lewis; Williams, Rebekah L.; Hall, James A.; Downs, Stephen M. (Elsevier, 2018-02)

  Purpose The objective of this study was to determine the effectiveness of computer-based screening and physician feedback to guide adolescent depression management within primary care. Methods We conducted a prospective ...
• Differentiation, Evaluation, and Application of Human Induced Pluripotent Stem Cell–Derived Endothelial Cells 

  Lin, Yang; Gil, Chang-Hyun; Yoder, Mervin C. (AHA, 2017-11)

  The emergence of induced pluripotent stem cell (iPSC) technology paves the way to generate large numbers of patient-specific endothelial cells (ECs) that can be potentially delivered for regenerative medicine in patients ...
• Prenatal inflammation exposure-programmed cardiovascular diseases and potential prevention 

  Deng, Youcai; Song, Liang; Nie, Xuqiang; Shou, Weinian; Li, Xiaohui (Elsevier, 2018)

  In recent years, the rapid development of medical and pharmacological interventions has led to a steady decline in certain noncommunicable chronic diseases (NCDs), such as cancer. However, the overall incidence of ...
• Transcriptional profiling of the ductus arteriosus: Comparison of rodent microarrays and human RNA sequencing 

  Yarboro, Michael T.; Durbin, Matthew D.; Herington, Jennifer L.; Shelton, Elaine L.; Zhang, Tao; Ebby, Cris G.; Stoller, Jason Z.; Clyman, Ronald I.; Reese, Jeff (Elsevier, 2018)

  DA closure is crucial for the transition from fetal to neonatal life. This closure is supported by changes to the DA’s signaling and structural properties that distinguish it from neighboring vessels. Examining transcriptional ...
• Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects 

  Cowan, Jason R.; Tariq, Muhammad; Shaw, Chad; Rao, Mitchell; Belmont, John W.; Lalani, Seema R.; Smolarek, Teresa A.; Ware, Stephanie M. (Royal Society, 2016-12-19)

  Genomic disorders and rare copy number abnormalities are identified in 15–25% of patients with syndromic conditions, but their prevalence in individuals with isolated birth defects is less clear. A spectrum of congenital ...
• Rationale for the Cytogenomics of Cardiovascular Malformations Consortium: A Phenotype Intensive Registry Based Approach 

  Hinton, Robert B.; McBride, Kim L.; Bleyl, Steven B.; Bowles, Neil E.; Border, William L.; Garg, Vidu; Smolarek, Teresa A.; Lalani, Seema R.; Ware, Stephanie M. (MDPI, 2015-04-29)

  Cardiovascular malformations (CVMs) are the most common birth defect, occurring in 1%-5% of all live births. Although the genetic contribution to CVMs is well recognized, the genetic causes of human CVMs are identified ...
• Practice Variation in the Immediate Postoperative Care of Pediatric Kidney Transplantation: A National Survey 

  Abu-Sultaneh, Samer; Hobson, Michael J.; Wilson, Amy C.; Goggins, William C.; Nitu, Mara E.; Lutfi, Riad (Elsevier, 2017-11)

  Introduction Advances in organ allocation, surgical technique, immunosuppression, and long-term follow-up have led to a significant improvement in kidney transplant outcomes. Although there are clear recommendations for ...
• Altered angiogenesis as a common mechanism underlying preterm birth, small for gestational age, and stillbirth in women living with HIV 

  Conroy, Andrea L.; McDonald, Chloe R.; Gamble, Joel L.; Olwoch, Peter; Natureeba, Paul; Cohan, Deborah; Kamya, Moses R.; Havlir, Diane V.; Dorsey, Grant; Kain, Kevin C. (Elsevier, 2017-12)

  Background Angiogenic processes in the placenta are critical regulators of fetal growth and impact birth outcomes, but there are limited data documenting these processes in HIV-infected women or women from low-resource ...
• Adolescent Sexual Behavior Research: Perspectives of Investigators, IRB Members, and IRB Staff about Risk Categorization and IRB Approval 

  McGregor, Kyle A.; Hensel, Devon J.; Waltz, Amy C.; Molnar, Elizabeth; Ott, Mary A. (The Hastings Center, 2017)
• Type I interferon signaling facilitates the development of IL-10-producing effector CD8+ T cells during influenza virus infection 

  Jiang, Li; Yao, Shuyu; Huang, Su; Wright, Jeffrey; Braciale, Thomas J.; Sun, Jie (Wiley, 2016-12)

  Recent evidence has suggested that IL-10-producing effector CD8+ T cells play an important role in regulating excessive inflammation during acute viral infections. However, the cellular and molecular cues regulating the ...
• Intensivist-based deep sedation using propofol for pediatric outpatient flexible bronchoscopy 

  Abulebda, Kamal; Abu-Sultaneh, Samer; Ahmed, Sheikh Sohail; Moser, Elizabeth A S; McKinney, Renee C; Lutfi, Riad (Baishideng Publishing Group, 2017-11-04)

  AIM To evaluate the safety and efficacy of sedating pediatric patients for outpatient flexible bronchoscopy. METHODS A retrospective chart review was conducted for all children, age 17 years or under who underwent ...
• Adolescent transgender health: Awareness does not equal resources 

  Chen, Melinda; Fuqua, John (Springer Verlag, 2016-12)
• Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia 

  Opoka, Robert O.; Bangirana, Paul; Idro, Richard; Shabani, Estela; Namazzi, Ruth; John, Chandy C. (Wiley, 2018-01)

  Retrospective studies suggest that there is high mortality in children with sickle cell anemia (SCA) and severe malaria. We assessed mortality in Ugandan children with severe malarial anemia (SMA, n = 232) or cerebral ...
• The Role of MDM2 in Promoting Genome Stability versus Instability 

  Saadatzadeh, M. Reza; Elmi, Adily N.; Pandya, Pankita H.; Bijangi-Vishehsaraei, Khadijeh; Ding, Jixin; Stamatkin, Christopher W.; Cohen-Gadol, Aaron A.; Pollok, Karen E. (MDPI, 2017-10-23)

  In cancer, the mouse double minute 2 (MDM2) is an oncoprotein that contributes to the promotion of cell growth, survival, invasion, and therapeutic resistance. The impact of MDM2 on cell survival versus cell death is complex ...
• Gender Differences in Risk Factors for Adolescent Binge Drinking and Implications for Intervention and Prevention 

  Dir, Allyson L.; Bell, Richard L.; Adams, Zachary W.; Hulvershorn, Leslie A. (Frontiers Media, 2017-12-22)

  Alcohol use, particularly binge drinking (BD), is a major public health concern among adolescents. Recent national data show that the gender gap in alcohol use is lessening, and BD among girls is rising. Considering the ...
• Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) 

  Cheng, Katherine; Gupta, Sandeep K.; Kantor, Susanna; Kuhl, Jonathan T.; Aceves, Seema S.; Bonis, Peter A.; Capocelli, Kelley E.; Carpenter, Christina; Chehade, Mirna; Collins, Margaret H.; Dellon, Evan S.; Falk, Gary W.; Gopal-Srivastava, Rashmi; Gonsalves, Nirmala; Hirano, Ikuo; King, Eileen C.; Leung, John; Krischer, Jeffrey P.; Mukkada, Vincent A.; Schoepfer, Alain; Spergel, Jonathan M.; Straumann, Alex; Yang, Guang-Yu; Furuta, Glenn T.; Rothenberg, Marc E. (IOS Press, 2017-12-18)

  Eosinophilic gastrointestinal disorders (EGIDs) affect various segments of the gastrointestinal tract. Since these disorders are rare, collaboration is essential to enroll subjects in clinical studies and study the broader ...
• Role of the community pharmacist in emergency contraception counseling and delivery in the United States: current trends and future prospects 

  Rafie, Sally; Stone, Rebecca H.; Wilkinson, Tracey A.; Borgelt, Laura M.; El-Ibiary, Shareen Y.; Ragland, Denise (Dove Press, 2017-03-23)

  Women and couples continue to experience unintended pregnancies at high rates. In the US, 45% of all pregnancies are either mistimed or unwanted. Mishaps with contraceptives, such as condom breakage, missed pills, incorrect ...
• Retrospective Analysis of Factors Leading to Pediatric Tracheostomy Decannulation Failure. A Single-Institution Experience 

  Bandyopadhyay, Anuja; Cristea, A. Ioana; Davis, Stephanie D.; Ackerman, Veda L.; Slaven, James E.; Jalou, Hasnaa E.; Givan, Deborah C.; Daftary, Ameet (American Thoracic Society, 2017-01)

  RATIONALE: There is a lack of evidence regarding factors associated with failure of tracheostomy decannulation. OBJECTIVES: We aimed to identify characteristics of pediatric patients who fail a tracheostomy decannulation ...
• Mental health care for youth with rheumatologic diseases - bridging the gap 

  Davis, Alaina M.; Rubinstein, Tamar B.; Rodriguez, Martha; Knight, Andrea M. (BMC, 2017-12-28)

  Youth with rheumatologic diseases have a high prevalence of comorbid mental health disorders. Individuals with comorbid mental health disorders are at increased risk for adverse outcomes related to mental health as well ...
• Sleep in children with type 1 diabetes and their parents in the T1D Exchange 

  Jaser, Sarah S.; Foster, Nicole C.; Nelson, Bryce A.; Kittelsrud, Julie M.; DiMeglio, Linda A.; Quinn, Maryanne; Willi, Steven M.; Simmons, Jill H. (Elsevier, 2017-11)

  Objectives Sleep has physiological and behavioral impacts on diabetes outcomes, yet little is known about the impact of sleep disturbances in children with type 1 diabetes. The current study sought to characterize sleep ...

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