Department of Pediatrics

 

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Recent Submissions

  • Auger, Katherine A.; Mueller, Emily L.; Weinberg, Steven H.; Forster, Catherine; Shah, Anita; Wolski, Christine; Mussman, Grant; Ipsaro, Anna Jolanta; Davis, Matthew M. (Elsevier, 2016-03)
    Objective To validate the accuracy of pre-encounter hospital designation as a novel way to identify unplanned pediatric readmissions and describe the most common diagnoses for unplanned readmissions among children. Study ...
  • Sharma, Richa; Nalepa, Grzegorz (AAP, 2016-03)
    Diagnostic evaluation and management of children with chronic pancytopenia is highly complex. (1)(2)(3) Clinicians should be aware of the subtle signs and symptoms of acquired and congenital childhood pancytopenias to ...
  • Zucker, Jacob; Temm, Constance; Czader, Magdalena; Nalepa, Grzegorz (Wiley, 2016-05)
    We describe a child with dyserythropoietic anemia, thrombocytosis, functional platelet defect, and megakaryocyte dysplasia. We show that (i) this constellation of hematopoietic abnormalities was due to a germline mutation ...
  • Hensel, Devon J.; Sorge, Brandon H. (Elsevier, 2014-12)
    PURPOSE: Emerging literature suggests that the emotional and behavioral experience in young women's romantic/sexual relationships may link to their academic success. However, existing studies' reliance on retrospective ...
  • Burns, Stephen F.; Lee, SoJung; Bacha, Fida; Tfayli, Hala; Hannon, Tamara S.; Arslanian, Silva A. (Elsevier, 2014-12)
    PURPOSE: To compare atherogenic lipoprotein particles and vascular smooth muscle biomarkers in overweight youth with pre-diabetes (PD) vs. normal glucose tolerance (NGT). METHODS: 144 adolescents (60 black, 84 white; 102 ...
  • Misurac, Jason; Nichols, Kristen R.; Wilson, Amy C. (Springer, 2016-02)
    Hypertension in children is common, and the prevalence of primary hypertension is increasing with the obesity epidemic and changing dietary choices. Careful measurement of blood pressure is important to correctly diagnose ...
  • Rigby, Mark R.; Harris, Kristina M.; Pinckney, Ashley; DiMeglio, Linda A.; Rendell, Marc S.; Felner, Eric I.; Dostou, Jean M.; Gitelman, Stephen E.; Griffin, Kurt J.; Tsalikian, Eva; Gottlieb, Peter A.; Greenbaum, Carla J.; Sherry, Nicole A.; Moore, Wayne V.; Monzavi, Roshanak; Willi, Steven M.; Raskin, Philip; Keyes-Elstein, Lynette; Long, S. Alice; Kanaparthi, Sai; Lim, Noha; Phippard, Deborah; Soppe, Carol L.; Fitzgibbon, Margret L.; McNamara, James; Nepom, Gerald T.; Ehlers, Mario R. (American Society for Clinical Investigation, 2015-08-03)
    BACKGROUND: Type 1 diabetes (T1D) results from destruction of pancreatic β cells by autoreactive effector T cells. We hypothesized that the immunomodulatory drug alefacept would result in targeted quantitative and qualitative ...
  • Yao, S.; Jiang, L.; Moser, E. K.; Jewett, L. B.; Wright, J.; Du, J.; Zhou, B.; Davis, S. D.; Krupp, N. L.; Braciale, T. J.; Sun, J. (Nature Publishing Group, 2015-12)
    Respiratory syncytial virus (RSV) infection is a leading cause of severe lower respiratory tract illness in young infants, the elderly and immunocompromised individuals. We demonstrate here that the co-inhibitory molecule ...
  • Prasain, Nutan; Lee, Man Ryul; Vemula, Sasidhar; Meador, Jonathan Luke; Yoshimoto, Momoko; Ferkowicz, Michael J.; Fett, Alexa; Gupta, Manav; Rapp, Brian M.; Saadatzadeh, Mohammad Reza; Ginsberg, Michael; Elemento, Olivier; Lee, Younghee; Voytik-Harbin, Sherry L.; Chung, Hyung Min; Hong, Ki Sung; Reid, Emma; O'Neill, Christina L.; Medina, Reinhold J.; Stitt, Alan W.; Murphy, Michael P.; Rafii, Shahin; Broxmeyer, Hal E.; Yoder, Mervin C. (Nature Publishing Group, 2014-11)
    The ability to differentiate human pluripotent stem cells into endothelial cells with properties of cord-blood endothelial colony-forming cells (CB-ECFCs) may enable the derivation of clinically relevant numbers of highly ...
  • Bennett, William E.; Hendrix, Kristin S.; Thompson-Fleming, Rachel T.; Downs, Stephen M.; Carroll, Aaron E. (Springer-Verlag, 2014-07)
    Both the American Academy of Pediatrics (AAP) and the Institute of Medicine (IOM) recommend delaying the introduction of cow's milk until after 1 year of age due to its low absorbable iron content. We used a novel computerized ...
  • Reynolds, Grace L.; Fisher, Dennis G.; Laurenceau, Jean-Philippe; Fortenberry, J. Dennis (Springer-Verlag, 2015-12)
    Women (N = 138) with histories of illicit drug use were recruited into an electronic diary study that used Android smartphones for data collection. The diary was to be completed each day for 12 weeks using an "app" created ...
  • Cerabona, Donna; Sun, Zejin; Nalepa, Grzegorz (Elsevier, 2016-05)
    Fanconi anemia (FA) is an inherited disorder of genomic instability associated with high risk of myelodysplasia and acute myeloid leukemia (AML). Young mice deficient in FA core complex genes do not naturally develop cancer, ...
  • Parker, Damien; Karmazyn, Boaz; Steiner, Steven J. (Lippincott, Williams, and Wilkins, 2016-03)
    Objectives: To assess whether small bowel imaging conducted at the time of diagnosis could be used as a predictor of small bowel surgical intervention in a pediatric Crohn's disease patient population. Methods: A ...
  • Nelson, Robert P.; Khawaja, Muhammad Rizwan; Perkins, Susan M.; Elmore, Lindsey; Mumaw, Christen L.; Orschell, Christie; Paczesny, Sophie (Elsevier, 2014-11)
    Five candidate plasma biomarkers (suppression of tumorogenesis 2 [ST2], regenerating islet-derived-3α [REG3α], elafin, tumor necrosis factor receptor 1 [TNFR1], and soluble IL-2 receptor-alpha [sIL2Rα]) were measured at ...
  • Mueller, Emily L.; Croop, James; Carroll, Aaron E. (Taylor & Francis, 2016)
    Fever and neutropenia (FN) is a common precipitant for hospitalization among children with cancer, but hospital utilization trends are not well described. This study describes national trends for hospital discharges for ...
  • Kobayashi, Michihiro; Chen, Sisi; Gao, Rui; Bai, Yunpeng; Zhang, Zhong-Yin; Liu, Yan (Landes Bioscience, 2014)
    The phosphatases of regenerating liver (PRLs), consisting PRL1, PRL2 and PRL3, are dual-specificity protein phosphatases that have been implicated as biomarkers and therapeutic targets in several solid tumors. However, ...
  • Bendaly, Edgard A.; DiMeglio, Linda A.; Fadel, William F.; Hurwitz, Roger A. (Springer, 2015-04)
    Background Children with chronic diseases are at risk for low bone mineral density (BMD). There are no studies of BMD in children with congenital heart disease and particularly SV. Children with this defect are often ...
  • Onish, Chie; Mori-Kimachi, Satomi; Hirade, Tomohiro; Abe, Mariko; Taketani, Takeshi; Suzumiya, Junji; Sugimoto, Toshitsugu; Yamaguchi, Seiji; Kapur, Reuben; Fukuda, Seiji (American Society for Biochemistry and Molecular Biology, 2014-11-07)
    Internal tandem duplication mutations in the Flt3 gene (ITD-FLT3) enhance cell migration toward the chemokine Cxcl12, which is highly expressed in the therapy-protective bone marrow niche, providing a potential mechanism ...
  • Parashette, Kalyan Ray; Waseem, Shamaila; Horn, Debra; Shah, Aali; Croffie, Joseph (Lippincott, Williams, and Wilkins, 2015-12)
    Objective: The aim of the present study was to study the effect of octreotide on colonic motility in pediatric patients with recalcitrant chronic constipation/encopresis and other suspected colonic motility disorders. Methods: ...
  • Benneyworth, Brian D.; Bennett, William E.; Carroll, Aaron E. (Springer (Biomed Central Ltd.), 2015-11-19)
    BACKGROUND: Inpatient administrative data sources describe the care provided to hospitalized children. The Kids' Inpatient Database (KID) provides nationally representative estimates, while the Pediatric Health Information ...

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