Department of Pediatrics

Recent Submissions

  • Sharp, Sacha; Hixson, Ashley; Stumpff, Julia C; Williamson, Francesca (2022-06-14)
    Background: Few research studies examine medical students and residents with intersectional identities. In the emerging literature, data on Black women’s experiences may be misrepresented and misinterpreted as studies ...
  • Sharp, Sacha; Hixson, Ashley; Stumpff, Julia C.; Williamson, Francesca (2022-04-23)
    Few research studies examine medical students and residents with intersectional identities. In the emerging literature, data on Black women’s experiences may be misrepresented and misinterpreted as studies aggregate data ...
  • Chen, Xinyun; Liu, Ying; Xu, Chen; Ba, Lina; Liu, Zhuo; Li, Xiuya; Huang, Jie; Simpson, Ed; Gao, Hongyu; Cao, Dayan; Sheng, Wei; Qi, Hanping; Ji, Hongrui; Sanderson, Maria; Cai, Chen-Leng; Li, Xiaohui; Yang, Lei; Na, Jie; Yamamura, Kenichi; Liu, Yunlong; Huang, Guoying; Shou, Weinian; Sun, Ning (Springer Nature, 2021-01-04)
    The RNA-binding protein QKI belongs to the hnRNP K-homology domain protein family, a well-known regulator of pre-mRNA alternative splicing and is associated with several neurodevelopmental disorders. Qki is found highly ...
  • Caston, Rachel A.; Shah, Fenil; Starcher, Colton L.; Wireman, Randall; Babb, Olivia; Grimard, Michelle; McGeown, Jack; Armstrong, Lee; Tong, Yan; Pili, Roberto; Rupert, Joseph; Zimmers, Teresa A.; Elmi, Adily N.; Pollok, Karen E.; Motea, Edward A.; Kelley, Mark R.; Fishel, Melissa L. (Wiley, 2021-01)
    With a plethora of molecularly targeted agents under investigation in cancer, a clear need exists to understand which pathways can be targeted simultaneously with multiple agents to elicit a maximal killing effect on the ...
  • Vachon, Madhura S.; Khalid, Myda; Tarr, Gillian A. M.; Hedberg, Craig; Brown, Jennifer A. (Elsevier, 2020-12)
    Background: Hemolytic uremic syndrome (HUS) is a life-threatening complication of Shiga toxin-producing Escherichia coli (STEC) infection. The relationship between STEC exposure and severity of clinical outcomes is not ...
  • Piñeros, Annie R.; Gao, Hongyu; Wu, Wenting; Liu, Yunlong; Tersey, Sarah A.; Mirmira, Raghavendra G. (MDPI, 2020-12)
    Obesity is closely associated with adipose tissue inflammation and insulin resistance. Dysglycemia and type 2 diabetes results when islet β cells fail to maintain appropriate insulin secretion in the face of insulin ...
  • Abu-El-Haija, Maisam; Lowe, Mark; Barth, Bradley; Bellin, Melena D.; Fishman, Douglas S.; Freedman, Steve; Gariepy, Cheryl; Giefer, Matthew J.; Gonska, Tanja; Heyman, Melvin B.; Himes, Ryan; Husain, Sohail; Lin, Tom K.; Liu, Quin; Mascarenhas, Maria R.; Maqbool, Asim; McFerron, Brian; Morinville, Veronique; Nathan, Jaimie; Ooi, Chee Y.; Perito, Emily; Pohl, John F.; Schwarzenberg, Sarah Jane; Shah, Uzma; Troendle, David; Werlin, Steven; Wilschanski, Michael; Zimmerman, Bridget; Uc, Aliye (Elsevier, 2020-06)
  • Qu, Xiuxia; Liu, Ying; Cao, Dayan; Chen, Jinghai; Liu, Zhuo; Ji, Hongrui; Chen, Yuwen; Zhang, Wenjun; Zhu, Ping; Xiao, Deyong; Li, Xiaohui; Shou, Weinian; Chen, Hanying (Elsevier, 2019-12-27)
    Bone morphogenetic protein 10 (BMP10) is a cardiac peptide growth factor belonging to the transforming growth factor β superfamily that critically controls cardiovascular development, growth, and maturation. It has been ...
  • Battaglia, Manuela; Ahmed, Simi; Anderson, Mark S.; Atkinson, Mark A.; Becker, Dorothy; Bingley, Polly J.; Bosi, Emanuele; Brusko, Todd M.; DiMeglio, Linda A.; Evans-Molina, Carmella; Gitelman, Stephen E.; Greenbaum, Carla J.; Gottlieb, Peter A.; Herold, Kevan C.; Hessner, Martin J.; Knip, Mikael; Jacobsen, Laura; Krischer, Jeffrey P.; Long, S. Alice; Lundgren, Markus; McKinney, Eoin F.; Morgan, Noel G.; Oram, Richard A.; Pastinen, Tomi; Peters, Michael C.; Petrelli, Alessandra; Qian, Xiaoning; Redondo, Maria J.; Roep, Bart O.; Schatz, Desmond; Skibinski, David; Peakman, Mark (American Diabetes Association, 2020-01)
    The clinical diagnosis of new-onset type 1 diabetes has, for many years, been considered relatively straightforward. Recently, however, there is increasing awareness that within this single clinical phenotype exists ...
  • Sims, Emily K.; Geyer, Susan; Bennett Johnson, Suzanne; Libman, Ingrid; Jacobsen, Laura M.; Boulware, David; Rafkin, Lisa E.; Matheson, Della; Atkinson, Mark A.; Rodriguez, Henry; Spall, Maria; Elding Larsson, Helena; Wherrett, Diane K.; Greenbaum, Carla J.; Krischer, Jeffrey; DiMeglio, Linda A. (American Diabetes Association, 2019-12)
    Objective: To better understand potential facilitators of individual engagement in type 1 diabetes natural history and prevention studies through analysis of enrollment data in the TrialNet Pathway to Prevention (PTP) ...
  • Ramsey, Laura B.; Ong, Henry H.; Schildcrout, Jonathan S.; Shi, Yaping; Tang, Leigh Anne; Hicks, J. Kevin; El Rouby, Nihal; Cavallari, Larisa H.; Tuteja, Sony; Aquilante, Christina L.; Beitelshees, Amber L.; Lemkin, Daniel L.; Blake, Kathryn V.; Williams, Helen; Cimino, James J.; Davis, Brittney H.; Limdi, Nita A.; Empey, Philip E.; Horvat, Christopher M.; Kao, David P.; Lipori, Gloria P.; Rosenman, Marc B.; Skaar, Todd C.; Teal, Evgenia; Winterstein, Almut G.; Obeng, Aniwaa Owusu; Salyakina, Daria; Gupta, Apeksha; Gruber, Joshua; McCafferty-Fernandez, Jennifer; Bishop, Jeffrey R.; Rivers, Zach; Benner, Ashley; Tamraz, Bani; Long-Boyle, Janel; Peterson, Josh F.; Van Driest, Sara L. (American Medical Association, 2020-12)
    Importance: Genotype-guided prescribing in pediatrics could prevent adverse drug reactions and improve therapeutic response. Clinical pharmacogenetic implementation guidelines are available for many medications commonly ...
  • Spence, John Paul; Lai, Dongbing; Reiter, Jill L.; Cao, Sha; Bell, Richard L.; Williams, Kent E.; Liang, Tiebing (Elsevier, 2020-12)
    Background: Paternal alcohol abuse is a well-recognized risk factor for the development of an alcohol use disorder (AUD). In addition to genetic and environmental risk factors, heritable epigenetic factors also have been ...
  • Adom, Djamilatou; Dillon, Stacey R.; Yang, Jinfeng; Liu, Hao; Ramadan, Abdulraouf; Kushekhar, Kushi; Hund, Samantha; Albright, Amanda; Kirksey, Maykala; Adeniyan, Titilayo; Lewis, Katherine E.; Evans, Lawrence; Wu, Rebecca; Levin, Steven D.; Mudri, Sherri; Yang, Jing; Rickel, Erika; Seaberg, Michelle; Henderson, Katherine; Gudgeon, Chelsea J.; Wolfson, Martin F.; Swanson, Ryan M.; Swiderek, Kristine M.; Peng, Stanford L.; Hippen, Keli L.; Blazar, Bruce R.; Paczesny, Sophie (American Association for the Advancement of Science, 2020-10-07)
    Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that mark activated T helper 17 (Th17) cells. The Th17 cell phenotype ...
  • Wong, Hector R.; Caldwell, J. Timothy; Cvijanovich, Natalie Z.; Weiss, Scott L.; Fitzgerald, Julie C.; Bigham, Michael T.; Jain, Parag N.; Schwarz, Adam; Lutfi, Riad; Nowak, Jeffrey; Allen, Geoffrey L.; Thomas, Neal J.; Grunwell, Jocelyn R.; Baines, Torrey; Quasney, Michael; Haileselassie, Bereketeab; Lindsell, Christopher J. (American Association for the Advancement of Science, 2019-11-13)
    Sepsis remains a major public health problem with no major therapeutic advances over the last several decades. The clinical and biological heterogeneity of sepsis have limited success of potential new therapies. Accordingly, ...
  • Villaverde, Chandler; Namazzi, Ruth; Shabani, Estela; Park, Gregory S.; Datta, Dibyadyuti; Hanisch, Benjamin; Opoka, Robert O.; John, Chandy C. (Oxford University Press, 2020-11-10)
    Background: Our prior study findings suggest that Plasmodium falciparum is the cause of disease in both malaria retinopathy-positive (RP) and most retinopathy-negative (RN) cerebral malaria (CM), and that absence of ...
  • Marete, Irene; Ekhaguere, Osayame; Bann, Carla M.; Bucher, Sherri L.; Nyongesa, Paul; Patel, Archana B.; Hibberd, Patricia L.; Saleem, Sarah; Goldenberg, Robert L.; Goudar, Shivaprasad S.; Derman, Richard J.; Garces, Ana L.; Krebs, Nancy F.; Chomba, Elwyn; Carlo, Waldemar A.; Lokangaka, Adien; Bauserman, Melissa; Koso‑Thomas, Marion; Moore, Janet L.; McClure, Elizabeth M.; Esamai, Fabian (BMC, 2020-12-17)
    Background: Birth weight (BW) is a strong predictor of neonatal outcomes. The purpose of this study was to compare BWs between global regions (south Asia, sub-Saharan Africa, Central America) prospectively and to determine ...
  • Kloepfer, Kirsten M.; Ross, Sydney E.; Hemmerich, Christopher M.; Slaven, James E.; Rusch, Douglas B.; Davis, Stephanie D. (Wiley, 2020-01)
  • Morrison, Christopher N.; Byrnes, Hilary F.; Miller, Brenda A.; Wiehe, Sarah E.; Ponicki, William R.; Wiebe, Douglas J. (Elsevier, 2019-12-01)
    Background: Adolescents who live near more alcohol outlets tend to consume more alcohol, despite laws prohibiting alcohol purchases for people aged <21 years. We examined relationships between adolescents' exposure to ...
  • Waide, Morgan L.; Polidoro, Rafael; Powell, Whitney L.; Denny, Joshua E.; Kos, Justin; Tieri, David A.; Watson, Corey T.; Schmidt, Nathan W. (Cell Press, 2020-12-15)
    Gut microbiota composition is associated with human and rodent Plasmodium infections, yet the mechanism by which gut microbiota affects the severity of malaria remains unknown. Humoral immunity is critical in mediating the ...

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