• Optineurin regulates osteoblastogenesis through STAT1 

  Mizuno, Noriyoshi; Iwata, Tomoyuki; Ohsawa, Ryosuke; Ouhara, Kazuhisa; Matsuda, Shinji; Kajiya, Mikihito; Matsuda, Yukiko; Kume, Kodai; Tada, Yui; Morino, Hiroyuki; Yoshimoto, Tetsuya; Ueki, Yasuyoshi; Mihara, Keichiro; Sotomaru, Yusuke; Takeda, Katsuhiro; Munenaga, Syuichi; Fujita, Tsuyoshi; Kawaguchi, Hiroyuki; Shiba, Hideki; Kawakami, Hideshi; Kurihara, Hidemi (Elsevier, 2020-05)

  A sophisticated and delicate balance between bone resorption by osteoclasts and bone formation by osteoblasts regulates bone metabolism. Optineurin (OPTN) is a gene involved in primary open-angle glaucoma and amyotrophic ...
• Bioactive Materials Subjected to Erosion/Abrasion and Their Influence on Dental Tissues 

  Viana, Í. E. L.; Alania, Y.; Feitosa, S.; Feitosa, A. B.; Braga, R. R.; Scaramucci, T. (Allen Press, 2020)

  Objective: The objective of this study was to evaluate the effect of erosion or erosion-abrasion on bioactive materials and adjacent enamel/dentin areas. Methods and Materials: Enamel and dentin blocks (4×4×2 mm) were ...
• Imatinib has minimal effects on inflammatory and osteopenic phenotypes in a murine cherubism model 

  Mukai, Tomoyuki; Akagi, Takahiko; Hiramatsu Asano, Sumie; Tosa, Ikue; Ono, Mitsuaki; Kittaka, Mizuho; Ueki, Yasuyoshi; Yahagi, Ayano; Iseki, Masanori; Oohashi, Toshitaka; Ishihara, Katsuhiko; Morita, Yoshitaka (Wiley, 2021)

  Objective Cherubism is a genetic disorder characterised by bilateral jawbone deformation. The associated jawbone lesions regress after puberty, whereas severe cases require surgical treatment. Although several drugs have ...
• Peer Led Team Learning in a Foundational IPE Curriculum 

  Romito, Laura; Daulton, Brittany J.; Stone, Cynthia; Pfeifle, Andrea L. (Pacific University Libraries, 2020-09)

  BACKGROUND The Peer Led Team Learning (PLTL) instructional model utilizes Peer Leaders, advanced students who mentor and guide student teams to collaborate on applied course concepts. PURPOSE To apply a modified PLTL model ...
• In-Vitro Model of Scardovia wiggsiae Biofilm Formation and Effect of Nicotine 

  Balhaddad, Abdulrahman A.; Ayoub, Hadeel M.; Gregory, Richard L. (Scielo, 2020-09)

  Recently, Scardovia wiggsiae has been reported to be strongly associated with caries formation. This study aimed to establish an in vitro model of S. wiggsiae biofilm and to investigate the effect of nicotine on S. wiggsiae ...
• Growth and viability of Streptococcus mutans in sucrose with different concentrations of Stevia rebaudiana Bertoni 

  Escobar, E.; Piedrahita, M.; Gregory, R. L. (Springer, 2020)

  Objective To evaluate total absorbance, planktonic growth, biofilm formation, viability, metabolic activity, and pH of Streptococcus mutans UA159 cultures when different dilutions of Stevia rebaudiana Bertoni were applied ...
• Effects of casein phosphopeptide-amorphous calcium phosphate crème on nicotine-induced Streptococcus mutans biofilm in vitro 

  Alawadhi, Naser B.; Lippert, Frank; Gregory, Richard L. (Springer, 2020)

  Objectives The aim of this study was to test the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) crème, or MI Paste™ (MIP), on nicotine-induced Streptococcus mutans biofilm. The experiment utilized ...
• Effects of Radiopaque Double Antibiotic Pastes on the Proliferation, Alkaline Phosphatase Activity and Mineral Deposition of Dental Pulp Stem Cells 

  Wu, Jennifer L.; McIntyre, Patrick W.; Hong, Jung Min; Yassen, Ghaeth H.; Bruzzaniti, Angela (Elsevier, 2020-09)

  Objective The aim of this study was to investigate the effects of two radiopaque agents, barium sulfate (BaSO4) or zirconium oxide (ZrO2) in double antibiotic paste (DAP), on the proliferation and mineral deposition of ...
• The Influence of Distance on Radiant Exposure and Degree of Conversion Using Different Light-Emitting-Diode Curing Units 

  Al-Zain, A.O.; Eckert, G. J.; Platt, J. A. (Allen Press, 2019-05)

  Objectives: To investigate the influence of curing distance on the degree of conversion (DC) of a resin-based composite (RBC) when similar radiant exposure was achieved using six different light-curing units (LCUs) and ...
• The Effects of Human Amniotic Fluid on Periodontal Ligament Fibroblast Cell Viability, Proliferation, and Cytokine/Growth Factor Expression 

  Ibraheem, Ahmed Gamil; Blanchard, Steven B.; Al-Hijji, Saleh Mohammed; Al-Nasr-Allah, Khaled; Windsor, L. Jack (Wolters Kluwer, 2019)

  Background: The importance of the amniotic fluid (AF) to the fetus is clear. However, very few studies have been published to examine the potential uses of this fluid in various areas such as tissue regeneration. AF contains ...
• Successful Conversion of Simulation-Based Interprofessional Education in a Pandemic 

  Romito, Laura; Pfeifle, Andrea L.; Weber, Zachary A.; Daulton, Brittany J. (Wiley, 2020-07-15)
• Effect of nicotine on biofilm formation of Streptococcus mutans isolates from smoking and non-smoking subjects 

  El-Ezmerli, Nasreen F.; Gregory, Richard L. (Taylor and Francis, 2019-01-01)

  Objectives: To investigate effects of nicotine on biofilm formation of Streptococcus mutans isolates from oral washes of smoker and non-smoker human subjects.Materials and methods: This study was conducted using 60 S. ...
• Influence of salivary conditioning and sucrose concentration on biofilm-mediated enamel demineralization 

  Ayoub, Hadeel M.; Gregory, Richard L.; Tang, Qing; Lippert, Frank (University of São Paulo, 2020)

  Introduction: The acquired pellicle formation is the first step in dental biofilm formation. It distinguishes dental biofilms from other biofilm types. Objective: To explore the influence of salivary pellicle formation ...
• RANKL-independent osteoclastogenesis in the SH3BP2 cherubism mice 

  Kittaka, Mizuho; Yoshimoto, Tetsuya; Hoffman, Henry; Levitan, Marcus Evan; Ueki, Yasuyoshi (Elsevier, 2020-03-27)

  Even though the receptor activator of the nuclear factor-κB ligand (RANKL) and its receptor RANK have an exclusive role in osteoclastogenesis, the possibility of RANKL/RANK-independent osteoclastogenesis has been the subject ...
• Physicochemical and Biological Properties of Novel Chlorhexidine-Loaded Nanotube-Modified Dentin Adhesive 

  Feitosa, Sabrina A.; Palasuk, Jadesada; Geraldeli, Saulo; Windsor, L. Jack; Bottino, Marco C. (Wiley, 2018-09-10)

  A commercially available three-step (etch-and-rinse) adhesive was modified by adding chlorhexidine (CHX)-loaded nanotubes (Halloysite®, HNT) at two concentrations (CHX10% and CHX20%). The experimental groups were: SBMP ...
• Injectable Highly Tunable Oligomeric Collagen Matrices for Dental Tissue Regeneration 

  Pankajakshan, Divya; Voytik-Harbin, Sherry L.; Nör, Jacques E.; Bottino, Marco C. (ACS, 2020-01)

  Current stem cell transplantation approaches lack efficacy, because they limit cell survival and retention and, more importantly, lack a suitable cellular niche to modulate lineage-specific differentiation. Here, we evaluate ...
• Analyzing Medication Documentation in Electronic Health Records: Dental Students’ Self-Reported Behaviors and Charting Practices 

  Burcham, Wesley K.; Romito, Laura M.; Moser, Elizabeth A.; Gitter, Bruce D. (ADEA, 2019-06)

  The aim of this two-part study was to assess third- and fourth-year dental students’ perceptions, self-reported behaviors, and actual charting practices regarding medication documentation in axiUm, the electronic health ...
• Fluoride Release from Two High-Viscosity Glass Ionomers after Exposure to Fluoride Slurry and Varnish 

  Nassar, Hani M.; Platt, Jeffrey A. (MDPI, 2019-11-15)

  The effect of brushing with different fluoride slurries on the fluoride release (FR) of different high-viscosity glass ionomer cements (GICs) was investigated. Fifty-eight discs were fabricated from two high-viscosity GICs ...
• Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function 

  Mohamad, Safa F.; Xu, Linlin; Ghosh, Joydeep; Childress, Paul J.; Abeysekera, Irushi; Himes, Evan R.; Wu, Hao; Alvarez, Marta B.; Davis, Korbin M.; Aguilar-Perez, Alexandra; Hong, Jung Min; Bruzzaniti, Angela; Kacena, Melissa A.; Srour, Edward F. (ASH, 2017-12)

  Networking between hematopoietic stem cells (HSCs) and cells of the hematopoietic niche is critical for stem cell function and maintenance of the stem cell pool. We characterized calvariae-resident osteomacs (OMs) and their ...
• Photoinhibition of Streptococcus mutans Biofilm-Induced Lesions in Human Dentin by Violet-Blue Light 

  Felix Gomez, Grace Gomez; Lippert, Frank; Ando, Masatoshi; Zandona, Andrea F.; Andrea F., George J.; Gregory, Richard L. (MDPI, 2019-12-11)

  This in vitro study determined the effectiveness of violet-blue light on Streptococcus mutans (UA159) biofilm induced dentinal lesions. Biofilm was formed on human dentin specimens in a 96-well microtiter plate and incubated ...

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