• Pyk2 and Megakaryocytes Regulate Osteoblast Differentiation and Migration Via Distinct and Overlapping Mechanisms 

  Eleniste, Pierre P.; Patel, Vruti; Posritong, Sumana; Zero, Odette; Largura, Heather; Cheng, Ying-Hua; Himes, Evan R.; Hamilton, Matthew; Baughman, Jenna; Kacena, Melissa A.; Bruzzaniti, Angela (Wiley, 2016-06)

  Osteoblast differentiation and migration are necessary for bone formation during bone remodeling. Mice lacking the proline-rich tyrosine kinase Pyk2 (Pyk2-KO) have increased bone mass, in part due to increased osteoblast ...
• Dimensionally stable and bioactive membrane for guided bone regeneration: An in vitro study 

  Rowe, Matthew J.; Kamocki, Krzysztof; Pankajakshan, Divya; Li, Ding; Bruzzaniti, Angela; Thomas, Vinoy; Blanchard, Steve B.; Bottino, Marco C. (Wiley Blackwell (John Wiley & Sons), 2016-04)

  Composite fibrous electrospun membranes based on poly(dl-lactide) (PLA) and poly(ε-caprolactone) (PCL) were engineered to include borate bioactive glass (BBG) for the potential purposes of guided bone regeneration (GBR). ...
• Role of endoplasmic reticulum stress in disuse osteoporosis 

  Li, Jie; Yang, Shuang; Li, Xinle; Liu, Daquan; Gao, Zhe; Zhao, Xiaoyu; Zhang, Jiuguo; Gou, Fanglin; Yokota, Hiroki; Zhang, Ping (Elsevier, 2017-04)

  Osteoporosis is a major skeletal disease with low bone mineral density, which leads to an increased risk of bone fracture. Salubrinal is a synthetic chemical that inhibits dephosphorylation of eukaryotic translation ...
• Ontogenetic and functional modularity in the rodent mandible 

  Menegaz, Rachel A.; Ravosa, Matthew J. (Elsevier, 2017)

  The material properties of diets consumed by juvenile individuals are known to affect adult morphological outcomes. However, much of the current experimental knowledge regarding dietary effects on masticatory form is derived ...
• Effects of Novel 3-dimensional Antibiotic-containing Electrospun Scaffolds on Dentin Discoloration 

  Porter, Margaret Louise A.; Münchow, Eliseu A.; Albuquerque, Maria T. P.; Spolnik, Kenneth J.; Hara, Anderson T.; Bottino, Marco C. (Elsevier, 2016-01)

  INTRODUCTION: Although intracanal application of the triple antibiotic paste (TAP) may offer advantages (eg, disinfection), this practice has been associated with significant drawbacks, including tooth discoloration. ...
• Fracture Resistance and Microleakage of Endocrowns Utilizing Three CAD-CAM Blocks 

  El-Damanhoury, Hatem M.; Haj-Ali, Reem N.; Platt, Jeffrey A. (2015-03)

  This study assessed marginal leakage and fracture resistance of computer-aided design/computer-aided manufacturing (CAD/CAM) fabricated ceramic crowns with intracoronal extensions into the pulp chambers of endodontically ...
• Effect of nicotine on cariogenic virulence of Streptococcus mutans 

  Li, Mingyun; Huang, Ruijie; Zhou, Xuedong; Qiu, Wei; Xu, Xin; Gregory, Richard L. (Springer, 2016-11)

  Nicotine has well-documented effects on the growth and colonization of Streptococcus mutans. This study attempts to investigate the effects of nicotine on pathogenic factors of S. mutans, such as the effect on biofilm ...
• Photo Inactivation of Streptococcus mutans Biofilm by Violet-Blue light 

  Gomez, Grace F.; Huang, Ruijie; MacPherson, Meoghan; Zandona, Andrea G. Ferreira; Gregory, Richard L. (Springer, 2016-09)

  Among various preventive approaches, non-invasive phototherapy/photodynamic therapy is one of the methods used to control oral biofilm. Studies indicate that light at specific wavelengths has a potent antibacterial effect. ...
• Residual antibiofilm effects of various concentrations of double antibiotic paste used during regenerative endodontics after different application times 

  Jenks, Daniel B.; Ehrlich, Ygal; Spolnik, Kenneth; Gregory, Richard L.; Yassen, Ghaeth H. (Elsevier, 2016-10)

  Objective We investigated the residual antibiofilm effects of different concentrations of double antibiotic paste (DAP) applied on radicular dentin for 1 or 4 weeks. Design Dentin samples were prepared (n = 120), ...
• Green tea catechin inhibits the activity and neutrophil release of Matrix Metalloproteinase-9. 

  Kim-Park, Wan K.; Allam, Eman S.; Palasuk, Jadesada; Kowolik, Michael; Park, Kichuel K.; Windsor, L. Jack (Elsevier, 2016-10)

  Green tea (Camellia sinensis; 綠茶 lǜ chá) extracts have been shown to possess anti-oxidant and anti-inflammatory effects in various cell types. Green tea extract (GTX) has been shown to significantly inhibit the activity ...
• Tissue-engineering-based strategies for regenerative endodontics 

  Albuquerque, M. T. P.; Valera, M. C.; Nakashima, M.; Nör, J. E.; Bottino, M. C. (SAGE Publications, 2014-12)

  Stemming from in vitro and in vivo pre-clinical and human models, tissue-engineering-based strategies continue to demonstrate great potential for the regeneration of the pulp-dentin complex, particularly in necrotic, ...
• XROMM analysis of tooth occlusion and temporomandibular joint kinematics during feeding in juvenile miniature pigs 

  Menegaz, Rachel A.; Baier, David B.; Metzger, Keith A.; Herring, Susan W.; Brainerd, Elizabeth L. (2015)

  Like humans, domestic pigs are omnivorous and thus are a common model for human masticatory function. Prior attempts to characterize food–tooth interactions and jaw movements associated with mastication have been limited ...
• A rate insensitive linear viscoelastic model for soft tissues 

  Zhang, Wei; Chen, Henry Y.; Kassab, Ghassan S. (Elsevier, 2007-08)

  It is well known that many biological soft tissues behave as viscoelastic materials with hysteresis curves being nearly independent of strain rate when loading frequency is varied over a large range. In this work, the rate ...
• Bimix antimicrobial scaffolds for regenerative endodontics 

  Palasuk, Jadesada; Kamocki, Krzysztof; Hippenmeyer, Lauren; Platt, Jeffrey A.; Spolnik, Kenneth J.; Gregory, Richard L.; Bottino, Marco C. (Elsevier, 2014-11)

  INTRODUCTION: Eliminating and/or inhibiting bacterial growth within the root canal system has been shown to play a key role in the regenerative outcome. The aim of this study was to synthesize and determine in vitro both ...
• Inhibitory effect of gels loaded with a low concentration of antibiotics against biofilm formation by Enterococcus faecalis and Porphyromonas gingivalis 

  Algarni, Amnah A.; Yassen, Ghaeth H.; Gregory, Richard L. (2015-09)

  We explored longitudinally the inhibitory effect of gels loaded with 1 mg/mL modified triple antibiotic paste (MTAP) or double antibiotic paste (DAP) against biofilm formation by Enterococcus faecalis and Porphyromonas ...
• Evaluation of selected properties of a new root repair cement containing surface pre-reacted glass ionomer fillers 

  Yassen, Ghaeth H.; Huang, Ruijie; Al-Zain, Afnan; Yoshida, Takamitsu; Gregory, Richard L.; Platt, Jeffrey A. (Springer, 2016)

  Objective This study evaluated selected properties of a prototype root repair cement containing surface pre-reacted glass ionomer fillers (S-PRG) in comparison to mineral trioxide aggregate (MTA) and intermediate ...
• In Vitro effects of Plantago major extract, aucubin and baicalein on Candida albicans biofilm formation, metabolic activity and cell surface hydrophobicity 

  Shirley, Karina Pezo; Windsor, L. Jack; Eckert, George J.; Gregory, Richard L. (Wiley, 2015)

  Purpose To determine the in vitro effectiveness of Plantago major extract, along with two of its active components, aucubin and baicalein, on the inhibition of Candida albicans growth, biofilm formation, metabolic activity, ...
• Effect of intracanal medicaments used in endodontic regeneration procedures on microhardness and chemical structure of dentin 

  Hamdon, Ghaeth Yassen; George, Joseph Eckert; Platt, Jeffrey Allen (Synapse, 2015-05)

  OBJECTIVES: This study was performed to investigate the effects of different intracanal medicaments on chemical structure and microhardness of dentin. MATERIALS AND METHODS: Fifty human dentin discs were obtained ...
• The use of traditional and novel techniques to determine the hardness and indentation properties of immature radicular dentin treated with antibiotic medicaments followed by ethylenediaminetetraacetic acid 

  Yassen, Ghaeth H.; Al‑Angari, Sarah S.; Platt, Jeffrey (Wolters Kluwer, 2014-10)

  OBJECTIVE: The objective was to investigate the effect of intracanal antibiotic medicaments followed by ethylenediaminetetraacetic acid (EDTA) on the indentation properties and hardness of radicular dentin using a BioDent ...
• The effects of radicular dentine treated with double antibiotic paste and ethylenediaminetetraacetic acid on the attachment and proliferation of dental pulp stem cells 

  Kim, Ki Wan; Yassen, Ghaeth H.; Ehrlich, Ygal; Spolnik, Kenneth; Platt, Jeffrey A.; Windsor, L. Jack (Wiley, 2015-10)

  Aim This study explored the effects of dentine treated with two concentrations of double antibiotic paste (DAP) and ethylenediaminetetraacetic acid (EDTA) on the attachment and proliferation of dental pulp stem cells ...

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