School of Medicine: Recent submissions

  • Estabrook, Neil C.; Corn, Jonathan B.; Ewing, Marvene M.; Cardenes, Higinia R.; Das, Indra J. (British Institute of Radiology, 2018-02)
    OBJECTIVE: Dosimetric evaluation of air column in gastrointestinal (GI) structures in intensity modulated radiation therapy (IMRT) of pancreatic cancer. METHODS: Nine sequential patients were retrospectively chosen ...
  • McElderry, Brenna M.; Mueller, Emily L.; Garcia, Abigail; Carroll, Aaron E.; Bennett, William E., Jr. (BMC, 2019-02-21)
    BACKGROUND: While it is commonly understood that a cancer diagnosis evokes feelings of fear, the effect of labeling a child's illness as "cancer" remains unstudied. We hypothesized that lower health utility scores would ...
  • You, Yingjian; Perkins, Abigail; Cisternas, Pablo; Muñoz, Braulio; Taylor, Xavier; You, Yanwen; Garringer, Holly J.; Oblak, Adrian L.; Atwood, Brady K.; Vidal, Ruben; Lasagna-Reeves, Cristian A. (BMC, 2019-02-26)
    Cerebral amyloid angiopathy (CAA) is typified by the cerebrovascular deposition of amyloid. Currently, there is no clear understanding of the mechanisms underlying the contribution of CAA to neurodegeneration. Despite the ...
  • Wang, S. Keisin; Green, Linden A.; Drucker, Natalie A.; Motaganahalli, Raghu L.; Fajardo, Andres; Murphy, Michael P. (Elsevier, 2018-07)
    OBJECTIVE: Currently, there are no accepted nonsurgical therapies that improve the delivery of blood-derived nutrients to patients with critical limb ischemia. Here, we describe the ongoing phase 1/2 Clinical and ...
  • Wang, S. Keisin; Miladore, Julia N.; Yee, Elliott J.; Liao, Jane L.; Donde, Nikunj N.; Motaganahalli, Raghu L. (Elsevier, 2019-06-29)
    This article describes brachial access to position a long sheath in the abdominal aorta in conjunction with a large caliber sheath via the femoral artery ipsilateral to the target site to deliver a 0.018 bodyfloss wire. ...
  • Oberlin, Brandon G.; Dzemidzic, Mario; Eiler, William J.A.; Carron, Claire R.; Soeurt, Christina M.; Plawecki, Martin H.; Grahame, Nicholas J.; O’Connor, Sean J.; Kareken, David A. (Springer, 2018-09)
    Rationale: Alcohol-associated stimuli capture attention, yet drinkers differ in the precise stimuli that become paired with intoxication. Objectives: Extending our prior work to examine the influence of alcoholism ...
  • Wiggs, Kelsey K.; Chang, Zheng; Quinn, Patrick D.; Hur, Kwan; Gibbons, Robert; Dunn, David; Brikell, Isabell; Larsson, Henrik; D'Onofrio, Brian M. (American Academy of Neurology, 2018-03-27)
    OBJECTIVE: Individuals with attention-deficit/hyperactivity disorder (ADHD) are at increased risk of seizures, but there is uncertainty about whether ADHD medication treatment increases risk among patients with and ...
  • Peck, Sarah A.; Hughes, Katlyn D.; Victorino, Jose F.; Mosley, Amber L. (Wiley, 2019-07)
    Processing and maturation of precursor RNA species is coupled to RNA polymerase II transcription. Co-transcriptional RNA processing helps to ensure efficient and proper capping, splicing, and 3' end processing of different ...
  • Taetzsch, Thomas; Benusa, Savannah; Levesque, Shannon; Mumaw, Christen L.; Block, Michelle L. (BMC, 2019-03-12)
    BACKGROUND: While NF-κB p50 function is impaired in central nervous system disease, aging in non-CNS tissues, and response to reactive oxygen species, the role of NF-κB p50 in aging-associated microglial pro-inflammatory ...
  • Chen, Di; Sahin, Afsun; Kam, Wendy R.; Liu, Yang; Darabad, Raheleh Rahimi; Sullivan, David A. (Elsevier, 2018-07)
    PURPOSE: Lipopolysaccharide (LPS), a bacterial endotoxin, is known to stimulate leuokotriene B4 (LTB4) secretion by human corneal (HCECs), conjunctival (HConjECs) and meibomian gland (HMGECs) epithelial cells. We ...
  • Vetrini, Francesco; McKee, Shane; Rosenfeld, Jill A.; Suri, Mohnish; Lewis, Andrea M.; Nugent, Kimberly Margaret; Roeder, Elizabeth; Littlejohn, Rebecca O.; Holder, Sue; Zhu, Wenmiao; Alaimo, Joseph T.; Graham, Brett; Harris, Jill M.; Gibson, James B.; Pastore, Matthew; McBride, Kim L.; Komara, Makanko; Al-Gazali, Lihadh; Al Shamsi, Aisha; Fanning, Elizabeth A.; Wierenga, Klaas J.; Scott, Daryl A.; Ben-Neriah, Ziva; Meiner, Vardiella; Cassuto, Hanoch; Elpeleg, Orly; Holder, J. Lloyd, Jr.; Burrage, Lindsay C.; Seaver, Laurie H.; Van Maldergem, Lionel; Mahida, Sonal; Soul, Janet S.; Marlatt, Margaret; Matyakhina, Ludmila; Vogt, Julie; Gold, June-Anne; Park, Soo-Mi; Varghese, Vinod; Lampe, Anne K.; Kumar, Ajith; Lees, Melissa; Holder-Espinasse, Muriel; McConnell, Vivienne; Bernhard, Birgitta; Blair, Ed; Harrison, Victoria; The DDD study; Muzny, Donna M.; Gibbs, Richard A.; Elsea, Sarah H.; Posey, Jennifer E.; Bi, Weimin; Lalani, Seema; Xia, Fan; Yang, Yaping; Eng, Christine M.; Lupski, James R.; Liu, Pengfei (BMC, 2019-02-28)
    BACKGROUND: Neurodevelopmental disorders are genetically and phenotypically heterogeneous encompassing developmental delay (DD), intellectual disability (ID), autism spectrum disorders (ASDs), structural brain abnormalities, ...
  • Sun, Gao; Jackson, Charles V.; Zimmerman, Karen; Zhang, Li-Kun; Finnearty, Courtney M.; Sandusky, George E.; Zhang, Guodong; Peterson, Richard G.; Wang, Yi-Xin (Jim) (BMC, 2019-03-18)
    Metabolic disorders such as insulin resistance, obesity, and hyperglycemia are prominent risk factors for the development of non-alcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH). Dietary rodent models employ ...
  • Mota, Roberto; Parry, Traci L.; Yates, Cecelia C.; Qiang, Zhaoyan; Eaton, Samuel C.; Mwiza, Jean Marie; Tulasi, Deepthi; Schisler, Jonathan C.; Patterson, Cam; Zaglia, Tania; Sandri, Marco; Willis, Monte S. (Elsevier, 2018-07)
    The muscle-specific ubiquitin ligase atrogin-1 (MAFbx) has been identified as a critical regulator of pathologic and physiological cardiac hypertrophy; it regulates these processes by ubiquitinating transcription factors ...
  • Huang, Xinxin; Trinh, Thao; Aljoufi, Arafat; Broxmeyer, Hal E. (Springer Nature, 2018-06)
    Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs) in the regulation of stem cell biology, specifically focusing on maintenance, differentiation, and stress responses in ...
  • Lawlor, Rita T.; Veronese, Nicola; Pea, Antonio; Nottegar, Alessia; Smith, Lee; Pilati, Camilla; Demurtas, Jacopo; Fassan, Matteo; Cheng, Liang; Luchini, Claudio (BMC, 2019-03-14)
    Alternative lengthening of telomeres (ALT) is a telomerase-independent mechanism used by a broad range of neoplasms to maintain telomere length, permitting uncontrolled replication during their progression. ALT has been ...
  • Mohammadian, Mahsa; Butt, Saira (Elsevier, 2019-06-25)
    Intracranial tuberculoma is one of the rare central nervous system manifestations of Mycobacterium tuberculosis (MTB), seen in only 1% of tuberculosis patients. It can manifest as single or multiple lesions, most commonly ...
  • Hsu, Yi-Hsiang; Estrada, Karol; Evangelou, Evangelos; Ackert-Bicknell, Cheryl; Akesson, Kristina; Beck, Thomas; Brown, Suzanne J.; Capellini, Terence; Carbone, Laura; Cauley, Jane; Cheung, Ching-Lung; Cummings, Steven R.; Czerwinski, Stefan; Demissie, Serkalem; Econs, Michael; Evans, Daniel; Farber, Charles; Gautvik, Kaare; Harris, Tamara; Kammerer, Candace; Kemp, John; Koller, Daniel L.; Kung, Annie; Lawlor, Debbie; Lee, Miryoung; Lorentzon, Mattias; McGuigan, Fiona; Medina-Gomez, Carolina; Mitchell, Braxton; Newman, Anne; Nielson, Carrie; Ohlsson, Claes; Peacock, Munro; Reppe, Sjur; Richards, J. Brent; Robbins, John; Sigurdsson, Gunnar; Spector, Timothy D.; Stefansson, Kari; Streeten, Elizabeth; Styrkarsdottir, Unnur; Tobias, Jonathan; Trajanoska, Katerina; Uitterlinden, André; Vandenput, Liesbeth; Wilson, Scott G.; Yerges-Armstrong, Laura; Young, Mariel; Zillikens, Carola; Rivadeneira, Fernando; Kiel, Douglas P.; Karasik, David (Wiley, 2019-07)
    Hip geometry is an important predictor of fracture. We performed a meta-analysis of GWAS studies in adults to identify genetic variants that are associated with proximal femur geometry phenotypes. We analyzed four phenotypes: ...
  • Coheley, L.M.; Kindler, J.M.; Laing, E.M.; Oshri, A.; Hill Gallant, K.M.; Warden, S.J.; Peacock, M.; Weaver, C.M.; Lewis, R.D. (Springer Nature, 2018-08)
    Eggs contain bioactive compounds thought to benefit pediatric bone. This cross-sectional study shows a positive link between childhood egg intake and radius cortical bone. If randomized trials confirm our findings, ...
  • Stine, Jonathan G.; Chalasani, Naga P. (Elsevier, 2017-02)
    Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents. Smoking can induce cytochrome P450 enzymes but this does ...
  • Chandler, Emmanuel; Ding, Lili; Gorbach, Pamina; Franco, Eduardo L.; Brown, Darron A.; Widdice, Lea E.; Bernstein, David I.; Kahn, Jessica A. (Elsevier, 2018-07)
    PURPOSE: The aims of this study were to determine prevalence of and factors associated with any human papillomavirus (HPV) and vaccine-type HPV among young men after vaccine introduction, stratified by vaccination ...

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