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Synthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-Synuclein synthesis, interleukin-1β release, and cholinergic action

Yu, Qian-sheng; Reale, Marcella; Kamal, Mohammad A.; Holloway, Harold W.; Luo, Weiming; Sambamurti, Kumar; Ray, Balmiki; Lahiri, Debomoy K.; Rogers, Jack T.; Greig, Nigel H. ( Bentham Science Publishers , 2013)

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Autor
- Greig, Nigel H. (1)
- Holloway, Harold W. (1)
- Kamal, Mohammad A. (1)
- Lahiri, Debomoy K. (1)
- Luo, Weiming (1)
- Ray, Balmiki (1)
- Reale, Marcella (1)
- Rogers, Jack T. (1)
- Sambamurti, Kumar (1)
- Yu, Qian-sheng (1)
Materia
- (+)-N1,N8-bisnorPosiphen; (−)-phenserine (1)
- (+)-N1-norPosiphen (1)
- (+)-N8-norPosiphen (1)
- Acetylcholinesterase (1)
- Alzheimer disease (1)
- Amyloid-β peptide (Aβ) (1)
- amyloid-β peptide (Aβ) (1)
- Amyloid-β precursor protein (APP) (1)
- amyloid-β precursor protein (APP) (1)
- Butyrylcholinesterase (1)
- ... más
Fecha
- 2013 (1)

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