Mythily Srinivasan

 

Recent Submissions

  • Srinivasan, Mythily; Meadows, Melinda L.; Maxwell, Lisa (Hindawi Publishing Corporation, 2018-02-01)
    Type 2 diabetes mellitus (T2DM) is emerging as a metabolic epidemic worldwide. Pathologically, dysregulation of many biological pathways precedes hyperglycemia and the clinical diagnosis of T2DM. Changing trajectories along ...
  • Negrini, Thais C.; Arthur, Rodrigo A.; Waeiss, Robert A.; Carlosa, Iracilda Z.; Srinivasan, Mythily (Wiley, 2014-02)
    The human skin not only provides passive protection as a physical barrier against external injury, but also mediates active surveillance via epidermal cell surface receptors that recognize and respond to potential invaders. ...
  • Srinivasan, Mythily; Lahiri, Debomoy K. (Springer, 2016)
    The central nervous system (CNS) is a large network of intercommunicating cells that function to maintain tissue health and homeostasis. Considerable evidence suggests that glucocorticoids exert both neuroprotective and ...
  • Jimson, Sudha; Murali, S.; Zunt, Susan L.; Goldblatt, Lawrence I.; Srinivasan, Mythily (2016)
    Background: Keratinocyte growth factor (KGF) is a potent epithelial mitogen that acts by binding the KGF receptors (KGFRs) expressed on epithelial cells and regulates proliferation and differentiation. The objective of ...
  • PRAKASAM, S.; SRINIVASAN, M. (Office of the Vice Chancellor for Research, 2012-04-13)
    Background: Saliva has potential to diagnose chronic periodontitis (CP). Changes in tissue-expression of pattern-recognition-receptors (PRRs), which recognize periodontal-pathogens, correlate with CP. It follows that ...
  • Chang, Hua-Chen; Han, Ling; Lewis, David; Tung, Chun-Yu; Srinivasan, Mythily; Robertson, Michael J.; Yeh, Wu-Kuang (Office of the Vice Chancellor for Research, 2013-04-05)
    Immune Peptide Therapeutics (IPT) LLC, an Indiana-based small business and its research partner Indiana University previously identified a novel property of lunasin as a distinct class of immune modulating agent that ...
  • Srinivasan, M.; Dunker, K. A.; Lahiri, Debomoy K.; Pollok, Karen E. (Office of the Vice Chancellor for Research, 2013-04-05)
    Multiple sclerosis (MS), a leading cause of neurological disability is an inflammatory demyelinating disease of the central nervous system (CNS). The clinical course of MS is highly variable ranging from isolated neurologic ...
  • Srinivasan, Mythily; Blackburn, Corinne; Mohamed, Mohamed; Sivagami, A. V.; Blum, Janice (Libertas Academia, 2015-02)
    The alarming increase in type 2 diabetes mellitus (T2DM) underscores the need for efficient screening and preventive strategies. Select protein biomarker profiles emerge over time during T2DM development. Periodic evaluation ...
  • Zhao, Alyssa; Blackburn, Corinne; Chin, Judith; Srinivasan, Mythily (2014-08)
    Background Dental caries is the most common microbial disease affecting mankind. Caries risk assessment methods, identification of biomarkers and vaccine development strategies are being emphasized to control the incidence ...
  • Chang, Hua-Chen; Tung, Chun-Yu; Lewis, David; Han, Ling; Srinivasan, Mythily; Robertson, Michael J.; Yeh, Wu-Kuang (Office of the Vice Chancellor for Research, 2014-04-11)
    Despite the plethora of immune modulating agents available in cancer treatment, their effectiveness relies on a functional immune system. However, the adverse side effects by chemotherapy impede the therapeutic benefits ...
  • Srinivasan, M.; Blackburn, C.; Lahiri, Debomoy K. (Office of the Vice Chancellor for Research, 2014-04-11)
    Many intermolecular interactions in a eukaryotic cell are mediated through protein-peptide interactions. For efficient interaction, the peptide scans the protein surface for a large enough pocket into which it anchors ...