p38 MAPK in pancreatic cancer: finding a protective needle in the haystack
Date
2014-12-01
Authors
Language
American English
Embargo Lift Date
Committee Members
Degree
Degree Year
Department
Grantor
Journal Title
Journal ISSN
Volume Title
Found At
American Association for Cancer Research
Abstract
Activated p38 MAPK alpha (pp38α) is a good prognostic marker in pancreatic ductal adenocarcinoma that could be used to personalize therapy. pp38α suppresses JNK-mediated proliferation, both in vitro and in vivo. These findings support the testing of combination therapies that include JNK targeting and/or suppressing negative regulators of pp38α.
Description
item.page.description.tableofcontents
item.page.relation.haspart
Cite As
Korc, M. (2014). p38 MAPK in Pancreatic Cancer: Finding a Protective Needle in the Haystack. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 20(23), 5866–5868. http://doi.org/10.1158/1078-0432.CCR-14-1543
ISSN
1078-0432
Publisher
Series/Report
Sponsorship
Major
Extent
Identifier
Relation
Journal
Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Rights
Publisher Policy
Source
PMC
Alternative Title
Type
Article
Number
Volume
Conference Dates
Conference Host
Conference Location
Conference Name
Conference Panel
Conference Secretariat Location
Permanent Link
Version
Author's manuscript