Naramore, SaraGupta, Sandeep K.2019-09-122019-09-122018-09Naramore, S., & Gupta, S. (2018). Nonesophageal Eosinophilic Gastrointestinal Disorders: Clinical Care and Future Directions. Journal of Pediatric Gastroenterology and Nutrition, 67(3), 318–321. https://doi.org/10.1097/MPG.0000000000002040https://hdl.handle.net/1805/20917Eosinophilic gastrointestinal disorders are a set of conditions with a wide range of clinical manifestations and treatment modalities. The disorders are suspected to result from an abnormal inflammatory response to allergen(s), and individuals may develop a relapsing or chronic disease, if the allergen is not eliminated. Mechanisms of disease pathogenesis, including the humoral immune response, need to be fully elucidated. A variety of therapies are used, though there is a lack of well-defined randomized, prospective studies. Other therapeutic options are needed as the current treatments have potential concerns; elimination diets may impair a child’s quality of life, and corticosteroids have adverse risks with long-term use. We review what is known about non-esophageal eosinophilic gastrointestinal disorders, and discuss research investigations which need to be conducted to facilitate diagnosis and enhance treatment methods.enPublisher Policydiet elimination therapyeosinophilic gastroenteritisintestinal eosinophiliaArticle