Sepulveda, EstebanFranco, Jose G.Trzepacz, Paula T.Gaviria, Ana M.Viñuelas, EvaPalma, JoseFerré, GiselaGrau, ImmaVilella, Elisabet2016-06-242016-06-242015-09Sepulveda, E., Franco, J. G., Trzepacz, P. T., Gaviria, A. M., Viñuelas, E., Palma, J., … Vilella, E. (2015). Performance of the Delirium Rating Scale-Revised-98 Against Different Delirium Diagnostic Criteria in a Population With a High Prevalence of Dementia. Psychosomatics, 56(5), 530–541. http://doi.org/10.1016/j.psym.2015.03.005https://hdl.handle.net/1805/10166Background Delirium diagnosis in elderly is often complicated by underlying dementia. Objective We evaluated performance of the Delirium Rating Scale-Revised-98 (DRS-R98) in patients with high dementia prevalence and also assessed concordance among past and current diagnostic criteria for delirium. Methods Cross-sectional analysis of newly admitted patients to a skilled nursing facility over 6 months, who were rated within 24–48 hours after admission. Interview for Diagnostic and Statistical Manual of Mental Disorders, 3rd edition-R (DSM)-III-R, DSM-IV, DSM-5, and International Classification of Diseases 10th edition delirium ratings, administration of the DRS-R98, and assessment of dementia using the Informant Questionnaire on Cognitive Decline in the Elderly were independently performed by 3 researchers. Discriminant analyses (receiver operating characteristics curves) were used to study DRS-R98 accuracy against different diagnostic criteria. Hanley and McNeil test compared the area under the curve for DRS-R98’s discriminant performance for all diagnostic criteria. Results Dementia was present in 85/125 (68.0%) subjects, and 36/125 (28.8%) met criteria for delirium by at least 1 classification system, whereas only 19/36 (52.8%) did by all. DSM-III-R diagnosed the most as delirious (27.2%), followed by DSM-5 (24.8%), DSM-IV-TR (22.4%), and International Classification of Diseases 10th edition (16%). DRS-R98 had the highest AUC when discriminating DSM-III-R delirium (92.9%), followed by DSM-IV (92.4%), DSM-5 (91%), and International Classification of Diseases 10th edition (90.5%), without statistical differences among them. The best DRS-R98 cutoff score was ≥14.5 for all diagnostic systems except International Classification of Diseases 10th edition (≥15.5). Conclusions There is a low concordance across diagnostic systems for identification of delirium. The DRS-R98 performs well despite differences across classification systems perhaps because it broadly assesses phenomenology, even in this population with a high prevalence of dementia.enPublisher Policydelirium diagnosisdementiaArticle