Aldosari, MohammadScaramucci, TaisLiu, Sean Shih-YaoWarrick-Polackoff, Janice M.Eckert, George J.Hara, Anderson T.2017-10-062017-10-062017Aldosari, M., Scaramucci, T., Liu, S. S.-Y., Warrick-Polackoff, J. M., Eckert, G. J. and Hara, A. T. (2017), Susceptibility of partially-desalivated rats to erosive tooth wear by calcium-supplemented beverages. Oral Dis. Accepted Author Manuscript. doi:10.1111/odi.12740https://hdl.handle.net/1805/14260Objectives To investigate the susceptibility of partially desalivated rats to erosive tooth wear (ETW); the anti-erosive effect of a calcium-supplemented beverage; and the quantification of ETW by microcomputed tomography (micro-CT). Methods The study population consisted of thirty-eight rats, divided into partially desalivated (n = 19) and normal salivary flow (n = 19). They were randomly allocated into three subgroups (n = 6–7): A-diet soda, B-diet soda + calcium, C-water (control). Solutions were provided ad libitum for 28 days, and the rats were euthanized afterwards. Each left hemi-mandible was scanned using micro-CT for enamel volume (three molars) calculation. Visual analysis of photographs of the lingual surface of first molars was performed independently by three blinded examiners. Data were statistically analysed (α = .05). Results Micro-CT revealed no significant differences between partially desalivated or normal groups. Rats consuming A had more enamel loss than those consuming B or C, which did not differ from each other. For visual analysis, desalivation did not affect ETW. Rats consuming C showed the lowest ETW, followed by B and then A, for both partially desalivated and normal rats. Spearman correlation between the two ETW quantification methods was −.65. Conclusions Partial desalivation did not increase ETW. Ca-containing beverage prevented ETW. Micro-CT quantified ETW, although it was not as sensitive as visual analysis.enPublisher Policydental erosioncalciumsalivaArticle