Korc, Murray2016-11-232016-11-232014-12-01Korc, M. (2014). p38 MAPK in Pancreatic Cancer: Finding a Protective Needle in the Haystack. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 20(23), 5866–5868. http://doi.org/10.1158/1078-0432.CCR-14-15431078-0432https://hdl.handle.net/1805/11495Activated p38 MAPK alpha (pp38α) is a good prognostic marker in pancreatic ductal adenocarcinoma that could be used to personalize therapy. pp38α suppresses JNK-mediated proliferation, both in vitro and in vivo. These findings support the testing of combination therapies that include JNK targeting and/or suppressing negative regulators of pp38α.en-USPublisher PolicyJNK Mitogen-Activated Protein KinasesmetabolismPancreatic Neoplasmspathologyp38 Mitogen-Activated Protein Kinasep38 MAPK in pancreatic cancer: finding a protective needle in the haystackArticle