Hara, Anderson T.Alwadai, GhadeerDiefenderfer, KimLipppert, FrankCook, Norman2019-07-012019-07-012019https://hdl.handle.net/1805/19765http://dx.doi.org/10.7912/C2/1633Indiana University-Purdue University Indianapolis (IUPUI)Background: Erosive tooth wear (ETW) is the loss of tooth substance due to chemo-mechanical action unrelated to bacteria. ETW affects approximately 46 percent of children/adolescents and 80 percent of adults in the U.S. Visual examination indices are available for the clinical assessment of ETW. Although useful, they are subjective and heavily based on the clinical experience of the examiner. Some quantitative techniques have been proposed and used for clinically assessing erosive tooth wear, including quantitative light-induced fluorescence, ultrasonic measurement, and more recently, polarization-sensitive optical coherence tomography (PS-OCT). Objective: The objective of this study was to explore the ability of PS-OCT to objectively measure erosive tooth wear on occlusal surfaces. Method: This study was conducted in two phases. In the first phase, 10 sound extracted human lower first premolars were selected and then exposed to tooth wear simulation gradually. PS-OCT and micro computed tomography (μ-CT) were used to evaluate enamel thickness of those premolars at the buccal cusp tip during the simulation. In phase 2, 40 extracted human lower first premolars with different severity levels of ETW on occlusal surfaces were selected based on the Basic Erosive Wear Examination (BEWE) index. A total of 10 teeth (n =10) were selected for each BEWE score (0/1/2/3). PS-OCT and μ-CT were used to evaluate the enamel thickness at the highest point on the occlusal surface. Results: There was good agreement between PS-OCT and μ-CT in both phases (phase 1: 0.89 and phase 2: 0.97) with no significant difference between PS-OCT and μ-CT. Conclusion: This result shows the potential of PS-OCT as reliable method for measuring enamel thickness and monitoring tooth wear progression on the occlusal surfaceen-USTomography, Optical CoherenceTooth WearThesis