Chen, YolandeCorey, Seth JoelKim, Oleg V.Alber, Mark S.2017-07-192017-07-192014Chen, Y., Corey, S. J., Kim, O. V., & Alber, M. S. (2014). Systems Biology of Platelet–Vessel Wall Interactions. Advances in Experimental Medicine and Biology, 844, 85–98. http://doi.org/10.1007/978-1-4939-2095-2_5https://hdl.handle.net/1805/13513Platelets are small, anucleated cells that participate in primary hemostasis by forming a hemostatic plug at the site of a blood vessel's breach, preventing blood loss. However, hemostatic events can lead to excessive thrombosis, resulting in life-threatening strokes, emboli, or infarction. Development of multi-scale models coupling processes at several scales and running predictive model simulations on powerful computer clusters can help interdisciplinary groups of researchers to suggest and test new patient-specific treatment strategies.en-USPublisher PolicyPlateletsBlood vesselsHemostasisThrombosisArticle